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Biomedical subjects

M Cavazza

Publications and source records attributed to M Cavazza.

22 records · Page 2Linked to original sources
PubMed1982

[Effect, on renal function, of a product rich in polyunsaturated fatty acids: results obtained in healthy subjects].

In 7 healthy subjects a 2,5 mg/Kg dose of i.v. phosphatidylcholine a drug with an high content of polyunsaturated fatty acids, caused variations in renal functionality as follows: a statistically significant increase of: urine flow, renal blood flow, glomerular filtration rate and sodium excretion. The above phenomena which resulted in a hypertonic poliuria, were detected during three 30 mins clearance periods. In other 5 subjects, a dose of lysine acetylsalicylate (10,5 mg/Kg) either suppressed the phenomena induced by the previous administration of phosphatidylcholine or prevented them to appear when the drug was given successively. Authors suggest that the data obtained may be ascribed to stimulation of local PG synthesis.

Aspirin↗
PubMed1979

[Effect of polyunsaturated fatty acids on experimental ulcer in the rat].

The increase of gastric mucosal defensive reachons under linoleic acid loading (20 mg/kg i.m. x 2 x 10 die; 140-220 mg/kg per os x 2 x 15 die), was evaluated in hydrocortisone treated rats (10 mg/kg i.m. x 2 x 10 die) and in rats stressed by immobilisation at a low temperature (at 4 degrees for 1 hour). The incidence and extent of gastric lesions were recorded, in both samples treated differentialy, and in control groups. Although the results were not similarly significant in every case, the capacity of the linoleic acid administrations in limiting the gastric mucose injury was evident. This protective capacity is not dependent on the lesive agent.

Animals↗