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Biomedical subjects

M Catala

Publications and source records attributed to M Catala.

88 records · Page 5Linked to original sources
PubMed1989

Spontaneous calcific cerebral embolus from a calcific aortic stenosis in a middle cerebral artery infarct.

Calcific emboli from a calcific aortic stenosis is an uncommon event, usually following local trauma, as from cardiac surgery or left heart catheterization or as a sequel to bacterial endocarditis. We report what we believe to be the first case of a spontaneous calcareous emboli demonstrated by cranial computed tomography. In this patient, systemic hypertension and mild aortic insufficiency may have caused increasing mechanical forces acting on the aortic cusps and may have precipitated embolism.

Aged↗
PubMed1985

[Colonic cancers. Results of surgical treatment and prognosis. 579 cases].

Between 1964 and 1981, 579 patients were operated upon for carcinoma of the colon. Hepatic and/or peritoneal metastases were present in 17.3%. Excision was performed in 530 cases (91.5%). Carcinomas of the left colon were usually treated by segmental resection. The peritoneum and lymph nodes were involved in 21.7% and 31% respectively of the patients who underwent resection. There were 6 post-operative deaths: 2 after exploratory or derivative surgery and 4 after excision of the tumour. All but 8 of the 395 patients operated upon before 1978 were followed up; 229 survived for more than 5 years, 58% of all operated patients and 63.6% of those who had their tumour excised. The 5-year survival rate was 6% after palliative excision and 73.6% after curative excision (caecum and ascending colon: 81%; transverse colon: 83%; descending colon: 65%; sigmoid flexure: 70.7%). Tumoral invasion in depth and lymph node involvement had a significant influence on prognosis. Based on Dukes' classification, the 5-year survival rates for stages A, B, C and D tumours were 89%, 75.4%, 54% and 6% respectively. The time elapsed between the first symptoms and the operation did not alter the prognosis which was slightly better in women and in young patients.

Adult↗
PubMed1985

[Multiple cancers of the colon and rectum. Incidence and results of surgical treatment].

Out of 1,528 patients operated upon for cancer of the colon or rectum between 1964 and 1984, synchronous carcinomas were observed in 63 patients, metachronous carcinomas in 36 patients and both synchronous and metachronous carcinomas, in 3 patients. Synchronous carcinomas were double in 59 patients and triple in 4 patients. In 80 p. 100 of the cases, the lesions were confined to the same surgical segment or to an adjacent segment. Rectal locations were less frequent (18 p. 100). Preoperative diagnosis was made in only 40 p. 100 of cases. Ninety-three p. 100 had resection, 81 p. 100 with a curative intent. Associated benign polyps were found on the resected specimen in 58 p. 100 of the cases. The resectability rate (93 p. 100) and 5-year survival rate (55 p. 100 of all operated patients and 67 p. 100 of those who underwent curative resection) were similar to those observed in our personal series of single carcinomas of the colon. A second cancer of the colon or rectum occurred in 36 patients. The time interval between the first and second carcinomas ranged from 1 to 24 years and the mean interval time was 6.3 years. Three of the 36 patients developed a third metachronous lesion. The distribution of the sites of successive carcinomas was similar to that of synchronous carcinomas; the second carcinoma was located in the rectum in 8 p. 100 of cases. Diagnosis of the second carcinoma was made through routine periodic colonoscopy in one third of the cases.(ABSTRACT TRUNCATED AT 250 WORDS)

Aged↗
PubMed1984

[Results of the surgical treatment of pancreatic cancer. Study of a series of 96 surgically treated patients].

From 1970 to 1980, 96 patients were operated on for pancreatic adenocarcinoma. Histological confirmation was obtained in all but 12 cases. The tumour was located in the right portion of the pancreas in 80 cases and in the left portion in 16 cases. Metastases were present in 39 patients, hepatic in 28 cases and peritoneal in 23 cases. Among the cases without metastasis, lymph node involvement was found in 12 patients out of 25. A partial pancreatectomy was carried out in 12 patients, by-pass operations in 50 patients and laparotomy only in 34 patients. The 30-day postoperative mortality rate was 12 p. 100 in the by-pass group; there was no postoperative death in the resected group. By 1982, all the patients were dead. The mean length of survival after Whipple resection was 15.6 months, after by-pass operations 8 months, after laparotomy 3.4 months, operative mortality excluded. When lymph nodes were involved (stage III), the mean duration of survival after resection (n = 4) was the same (i.e. 7,5 months) as that after by-pass operations. The period of survival after by-pass procedures only exceeded one year in 8 cases. After pancreatic resection, only one patient survived five years. These results show that the resectability rate of pancreatic carcinoma is very low. Pancreatic resection seems to be justified mainly in stage I and II tumors. However, prognosis of pancreatic carcinoma remains very poor and the 5-year survival rate after resection does not exceed 10 p. 100.

Adenocarcinoma↗
PubMed1981

[The conservative treatment of an isolated angiomyolipoma of the kidney on the basis of one case treated by tumorectomy ex-vivo (author's transl)].

The authors report a quite exceptional case of isolated angiomyolipoma of one kidney in the absence of any manifestation of phakomatosis. Discovery of the tumour led to special investigations which confirmed the solid and hypervascularised nature of the tumour. A doubt remained with regard to its precise nature, and hence an extended nephrectomy, though without damage to the vessels at the time of section. The kidney was cooled and preserved by perfusion which allowed time for adequate histological study. The diagnosis of angiomyolipoma being confirmed, without the slightest risk of dissemination if by chance it had not been a benign tumour, the kidney was transplanted into the lumbar fossa via its own vessels with an excellent result. The authors discuss two problems on the basis of this case: 1) That of preoperative diagnostic difficulties: the scanner provides valuable information when it reveals the presence of intra-tumoral fatty tissue. 2) Difficulties in management when the benign nature of the lesion cannot be confirmed before histological examination. The solution adopted: routine extended nephrectomy with ex-vivo perfusion of the kidney making it possible to obey the basic rules of oncology. Frozen section biopsy confirms the diagnosis of angiomyolipoma. It is then possible to auto-transplant the kidney after tumorectomy.

Adult↗
PubMedDate not supplied

Congenital intraspinal lipomas: histological analysis of 234 cases and review of the literature.

The clinical, radiologic, and pathologic data from a series of 234 patients hospitalized in the Pediatric Neurosurgical Department of the Necker-Enfants Malades Hospital, Paris, for congenital intraspinal lipomas and operated on from 1976 to 1995 were examined. Histological studies showed that these lesions may be simple lipomas, similar to those developing elsewhere in the body, or they may be more complex forms including in addition to the lipomatous component a variety of unusual ectopic tissues of ectodermal, mesodermal, and/or endodermal origin. These complex forms indica te the malformative nature of these tumors. When they contain elements that are truly foreign to the region, the possibility of teratoma with a tumoral potential should be considered. Data found in the literature and from Necker-Enfants Malades Hospital are discussed.

Child↗
PubMedDate not supplied

Nasal fossa malformations and paramedian facial cleft: new perspectives.

Choanal atresia may be associated with other cranio-facial malformations, including various degrees of nasal fossa malformation, and may be a part of paramedian facial clefts (as described by Tessier et al. [1977]). We identified five such cases with combined clinical elements corresponding to Tessier's paramedian facial cleft, including eyelid coloboma, mild to severe choanal and nasal fossa anomalies, ethmoidal hypoplasia and anterior skull base malformation, sometimes with proboscis lateralis and half-nose hypoplasia. These observations incited us, first, to elaborate a conception which accounts for the likely embryological mechanisms involved; second, to propose a new classification based on anatomical and pathogenic embryological considerations; and last, to propose the use of transpalatal approach to restore choanal permeability, since endonasal laser therapy is particularly dangerous in such cases.

Child, Preschool↗
PubMedDate not supplied

A destructive hemispheric cleft discovered in a female fetus.

The case of a female fetus who died at the 38th week of gestation is reported. Neuropathological examination disclosed a hemispheric cleft located in the medial part of the left frontal lobe. The cleft did not extend to the ventricle and was not a true schizencephaly. Furthermore, a focus of gliosis was evidenced by GFAP staining located in the superior bank of the cleft suggesting a destructive origin of the process. Maternal psychological stress occurring during the middle of the pregnancy could have favored hemodynamic disturbances acting on the fetal circulation.

Adult↗