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M Cassidy

Publications and source records attributed to M Cassidy.

81 records · Page 5Linked to original sources
PubMed1976

Automated analysis of antigen-stimulated lymphocytes.

Human peripheral blood lymphocytes were stimulated with phytohemagglutinin and tuberculin-purified protein derivative to determine if flow microfluorometric techniques had the sensitivity to detect high and low levels of blastogenic response. The deoxyribonucleic acid content of the lymphocytes was analyzed after culture. Blastogenic response was found to be measurable both sensitively and reproducibly. Tritiated thymidine incorporation measurements were also made. Preliminary experiments using inactivated Herpesvirion (type I) as a stimulant showed blastogenic response detectable by flow microfluorometric deoxyribonucleic acid measurements. Refinements of this technique may prove to be useful in the study of lymphocyte response to viral antigens in patient populations.

Autoanalysis↗
PubMed1975

Evaluation of the lymphocyte blastogenic response by rapid flow analysis.

The data presented show that the blastogenic response of human peripheral lymphocytes to mitogens and specific antigens can be easily evaluated with rapid flow analysis of mithramycin stained cells. The precision, reproducibility and rapidity of the method make it highly suitable to study lymphocyte response to antigens in patient populations.

Cell Division↗
PubMedDate not supplied

Tracking drug-resistant Streptococcus pneumoniae in Oregon: an alternative surveillance method.

With the emergence of drug-resistant Streptococcus pneumoniae, community-specific antimicrobial susceptibility patterns have become valuable determinants of empiric therapy for S. pneumoniae infections. Traditionally, these patterns are tracked by active surveillance for invasive disease, collection of isolates, and centralized susceptibility testing. We investigated whether a simpler and less expensive method aggregating existing hospital antibiograms--could provide community-specific antimicrobial susceptibility data. We compared 1996 active surveillance data with antibiogram data from hospital laboratories in Portland, Oregon. Of the 178 S. pneumoniae active surveillance isolates, 153 (86% [95% confidence interval (CI) = 80% to 91%]) were susceptible to penicillin. Of the 1,092 aggregated isolates used by hospitals to generate antibiograms, 921 (84% [95% CI = 82%-87%]) were susceptible to penicillin. With the exception of one hospital's erythromycin susceptibility results, hospital-specific S. pneumoniae susceptibilities to penicillin, cefotaxime, trimethoprim-sulfamethoxazole, and erythromycin from the two methods were statistically comparable. Although yielding fewer data than active surveillance, antibiograms provided accurate, community-specific drug-resistant S. pneumoniae data in Oregon.

Community-Acquired Infections↗
PubMedDate not supplied

Electronic cell volume (coulter volume) distribution of vaginal-cervical cytology samples.

Peripheral blood and buccal cells were used as "model" cell populations to indicate where in the electronic cell volume (ECV) spectrum the individual cell populations of vaginal and cervical irrigations would appear. Four clinical samples each representing a different stage of abnormality were evaluated and compared with the "model" cell populations. The pattern was the same for all of the clinical samples and correlated with the blood and buccal cell populations. Only two distinct ECV populations were observed, the inflammatory cells and the epithelial cells. There was no difference in pattern of any of the volume distributions to indicate abnormality to any degree.

Amplifiers, Electronic↗
PubMedDate not supplied

Resin-Bonded bridges: 1. Development and casting design.

This series of two articles will consider the developments and clinical techniques of resin-bonded bridges with the emphasis on methods for increasing success from a functional and aesthetic view point.

Dental Casting Technique↗
PubMedDate not supplied

Chylopericardium after orthotopic heart transplantation.

Chylopericardium is an infrequent cause of pericardial effusions after heart surgery and to our knowledge has not been reported after orthotopic transplantation. We report the occurrence of chylopericardium in a heart transplant recipient who was successfully treated with a pericardial window, pericardiocentesis, and a diet rich in medium-chain triglycerides.

Chyle↗
PubMedDate not supplied

An update on conventional fixed bridges:. 3. Planning ahead.

The first two articles in this series dealt with patient assessment and selection for bridgework and the available options in conventional bridgework design. Having decided to provide a conventional bridge for a patient, the practitioner must plan ahead so that the clinical execution of the bridge proceeds smoothly and successfully. Time taken to plan ahead carefully will always benefit both patient and operator.

Crown Lengthening↗