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Biomedical subjects

M Carothers

Publications and source records attributed to M Carothers.

3 recordsLinked to original sources

Aggressive surgery in the management of oral neoplasia.

Aggressive surgical techniques such as mandibulectomy and maxillectomy have become the standard surgical treatment for oral neoplasia. The development of these procedures has provided some hope for a cure or at least extended life span in animals with oral tumors. Although large segments of bone and soft tissue are usually removed, function and cosmesis are acceptable. Postoperative complications are common but are usually treatable. Best prognosis for long-term survival is for patients with benign tumors or early SCC. Less favorable results have been found with fibrosarcoma and MM. Continued research in adjunctive treatment of these tumors may further improve the results of combined surgical and medical management.

Animals

Hypercalcemia.

Elevated serum calcium occurs relatively uncommonly in dogs and rarely in cats. Hypercalcemia can serve as a marker of disease that enables diagnosis but may also contribute to development of lesions and the clinical signs of disease. Specific clinical signs do not necessarily accompany hypercalcemia, and its presence will frequently be unsuspected. Fortuitous hypercalcemia is often discovered after a review of serum biochemical profile results. This article emphasizes malignancy-associated hypercalcemia and the emergence of cholecalciferol rodenticide toxicity as an important cause of hypercalcemia, as well as its treatment.

Animals