Search PubMed⌕ Search

Biomedical subjects

M Canivet

Publications and source records attributed to M Canivet.

At least 55 records · Page 3Linked to original sources

[Induction of endogenous murine C-type viruses. Attempt at discrimination by the pI of polypeptide p30 and the aspect of cellular transformation].

Endogenous ecotropic and xenotropic murine C-type viruses induced in K-Balb-3T3 cells treated with iododeoxyuridine (IdU) were selected by infection of appropriate indicator cells. The isoelectric point (p1) of the major viral polypeptide (p30) was found to be 6.1 for the ecotropic virus (class I), and 5.7 for the xenotropic virus (class II). An isoelectric form (iso p30) of pl 6.5 was observed in the initial induction peak. In addition, the pattern of cellular alteration in NRK cells at its onset varied according to the pseudotype, the class I pseudotype inducing round cell foci while the foci associated with the class II pseudotype consisted of fusiform cells.

Animals↗

[Multiplication of murine C-type viruses in mouse teratocarcinoma cell lines].

The host-virus interactions of several murine C type viruses with cell lines established in vitro from a mouse teratocarcinoma were studied. The cells used in this study were the multipotential stem cells, or embryonal carcinoma cells, and the differentiated cells derived from a same tumor.

AKR murine leukemia virus↗

Replication of Mouse Sarcoma Virus (Moloney) and its helper in a human heteroploid cell line of malignant origin.

A human heteroploid cell line of malignant origin (J111) was infected with Mouse Moloney Sarcoma Virus. [MSV-M(MLV)]. The replication of the virus was demonstrated by different methods. After a few passages of infected cultures, the transforming component of MSV-M(MLV) disappeared from the supernatant fluids and cells. The non transforming helper component continued to be produced. The relatively low amount of helper virus released by the cells suggests a control of its replication in the J111 cellular system.

Aneuploidy↗