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Biomedical subjects

M Canis

Publications and source records attributed to M Canis.

At least 163 records · Page 9Linked to original sources
PubMed1987

[Ovarian cysts and celioscopy. Apropos 226 cases].

Tumours of the adnexae are frequent. In most cases it is necessary to look at them directly and to treat them surgically. Laparatomy is a heavy technique. For this reason we use the laparoscope to diagnose cystic lesions and to treat benign tumours. This retrospective study on 226 patients has given us the opportunity to assess the value of the laparoscope in these conditions. From the diagnostic point of view laparoscopy is reliable. No malignant tumour failed to be diagnosed (100% reliable), the anatomopathological examination of specimens in benign conditions was never wrong (100% reliable). Laparoscopy therefore is a reliable way of diagnosing the type of ovarian cyst. 180 patients were treated using the laparoscope (79.5%). The patients were followed up for 1 to 5 years. We have not had a recurrence of a cyst treated in this way. Each time a malignant tumour was diagnosed or even suspected the classical surgical approach by laparotomy was always carried out. For a trained surgeon laparoscopy seems to be a reliable method of diagnosing and treating. It possesses the very well-known advantages of minimal operative trauma and far less cost.

Adolescent↗
PubMed1986

Conservative laparoscopic treatment of 321 ectopic pregnancies.

From 1974 to 1984, 321 tubal pregnancies were treated conservatively with laparoscopic techniques. Fifteen cases (4.8%) required a subsequent laparotomy or second laparoscopic procedure because of retained trophoblastic tissue. Of 118 patients desiring subsequent pregnancy, 76 had an intrauterine pregnancy (64.4%) and 26 had a second ectopic pregnancy (22%). Eleven of 24 (45.8%) women attempting conception following conservative laparoscopic removal of an ectopic gestation from the sole remaining fallopian tube established an intrauterine pregnancy. In this same group, seven patients (29.2%) had a second ectopic pregnancy. The fertility results were also analyzed according to the previous history. The postoperative intrauterine pregnancy rate was 85.5% among 62 patients without a history of infertility (group I), compared with 41.1% among 56 patients with a history of infertility or a previous ectopic pregnancy (group II). The subsequent ectopic pregnancy rate in group I was 16.1% versus 28.6% in group II. This large series clearly demonstrates the relative safety and efficacy of conservative laparoscopic treatment of tubal pregnancies.

Adolescent↗
PubMed1986

[Celioscopic treatment of extra-uterine pregnancy].

The treatment of extrauterine pregnancy by coelioscopy is the most extreme refinement of coelioscopic surgery. It is recorded in the modern context of endoscopic surgery. This technique was received with reserve some years ago, when we presented the first case. After more than 250 cases the validity of the treatment has been established, and it has been adopted by other groups, foreigners in particular. It is applicable to non-ruptured tubal pregnancies, and necessitates an early diagnosis. Compared with techniques carried out by laparotomy, it offers the advantage of considerable gain of operative time, and of a considerable reduction in hospitalization, with excellent results on later fertility.

Endoscopy↗
PubMed1985

[Celioscopy in the early follow-up of salpingitis].

The authors report their findings in 34 cases of salpingitis that were diagnosed and controlled laparoscopically one month after treatment had been finished. Four different elements came up: persistence of inflammation, adhesions, tubal patency and the prognosis for future fertility. It would seem that these last three criteria depend greatly on the seriousness at first of the salpingitis, as opposed to the degree of persistent inflammation. The authors show how valuable laparoscopic drainage of a pyosalpinx is and how valuable laparoscopic control after salpingitis is. Having been given these features they can visualise a new approach to the diagnosis and treatment of pelvic infection.

Adolescent↗
PubMed1985

[Vaginal delivery after cesarean section: use of peridural analgesia and oxytocics. Apropos of 87 cases with cicatriceal proof].

The authors report on their experience delivering 87 women vaginally with previous cesarean sections. Epidural anesthesia does not appear to be contraindicated as long as the block is not higher than the level of the tenth thoracic dermatome. The use of an infusion of oxytocin should be accompanied by internal fetal heart monitoring. Furthermore, induction of labor with oxytocic agents appears preferable.

Anesthesia, Epidural↗
PubMed1984

[Congenital anomaly of serum pseudocholinesterase originating in neonatal respiratory distress].

Prolonged suxamethonium-induced apnoea was observed after obstetrical anaesthesia in a 30 year old woman with abnormal plasma cholinesterases (homozygous Ea1-Ea1). Flaccidity and apnoea in the child required controlled ventilation for 30 min. Possible mechanisms underlying prolonged apnoea after the use of suxamethonium for obstetrical anaesthesia are discussed. Atypical pseudocholinesterases were identified using quantitative dosage of enzymatic activity and inhibition of atypical pseudocholinesterases by dibucaine, fluoride, chloride, scoline and urea. This was carried out in the patient, her baby and family, thus identifying the genotype of the different family members.

Anesthesia, Obstetrical↗
PubMed1984

[Laparoscopy in the diagnosis and treatment of adnexal torsion].

13 uterine adnexal torsions were diagnosed by means of laparoscopy between June 1978 and October 1982. Laparoscopy is an opportunity for the adnexae to be untwisted, and gives precision to estimate the severity of the damage of the adnexae and to elucidate the aetiology. In ten patients, the treatment was performed by means of laparoscopy Three patients underwent immediate laparotomy: two for necrosis of the adnexae, one for a mucinous cystadenoma. The post-operative course was always uneventful. A second look laparoscopy was performed to check the anatomical recovery of primary severe ischaemic lesions (4 cases). The usefulness of laparoscopy in diagnosing torsion of the uterine adnexae is now well established. We can also treat by means of laparoscopy. Contra-indications to this management are necrosis of the adnexae and organic tumours.

Adnexal Diseases↗
PubMedDate not supplied

Management of adnexal masses: role and risk of laparoscopy.

Laparoscopic surgery has become the gold standard in the treatment of benign adnexal masses, whereas laparotomy remains the standard for the treatment of malignant tumors. The laparoscopic management of adnexal masses remains controversial because of the potential risks of cancer dissemination suggested by many case reports and national surveys. Experimental data show potential advantages and disadvantages for the laparoscopic treatment of gynecologic cancer. Since the risk of dissemination appears high when a large number of malignant cells are present, adnexal tumors with external growths and bulky lymph nodes may be considered contra-indications to CO(2) laparoscopy. Surgical diagnosis is the key to adequate management of adnexal masses. In our experience, laparoscopic diagnosis of malignancy is reliable after a careful pre-operative evaluation has been performed. Moreover, national surveys have revealed that despite suspicious laparoscopic findings, many malignant masses were considered benign at the outset. Using strict guidelines, laparoscopic diagnosis can be proposed for both non-suspicious and complex masses, thus avoiding many unnecessary laparotomies for benign masses suspicious at ultrasound. The more controversial limits of laparoscopic treatment are discussed. If a laparotomy was performed for all masses suspicious at surgery, 80% of the cases would be treated by laparoscopy. The role of laparoscopy for restaging and second-look operations for ovarian cancer requires further evaluation.

Adnexal Diseases↗
PubMedDate not supplied

Laparoscopic hysterectomy. A preliminary study.

Thirty-three patients were selected for laparoscopic hysterectomy and operated on in the Department of Obstetrics, Gynecology and Reproductive Medicine of Clermont-Ferrand University Hospital. Surgical techniques included blunt dissection with scissors and bipolar coagulation to achieve hemostasis. A case was considered successful when all the uterine vessels were treated by laparoscopy. Twenty-four cases were completed laparoscopically (72.7%). None of these patients had postoperative bleeding; 22 had an uneventful postoperative recovery. Nine procedures were converted to laparotomy (27.3%), five because of a difficult or unsatisfactory hemostasis. We conclude that in selected cases, a total hysterectomy can be performed safely by experienced laparoscopists. Further technological progress is necessary to make this procedure more acceptable. Its value as compared to the others will have to be demonstrated.

Adult↗
PubMedDate not supplied

Human endometriosis-derived permanent cell line (FbEM-1): establishment and characterization.

A human epithelial-like cell line derived from peritoneal implants from a patient with gonadotrophin-releasing hormone (GnRH) agonist-resistant endometriosis graded as stage IVd according to the American Fertility Society classification was established in vitro. This cell line, designated FbEM-1, exhibited an epithelial-like morphology, grew in suspension and was immunoreactive for cytokeratins 8, 18, 19, vimentin and human leukocyte class I antigens. The cultured cells were negative for various haematopoietic cell markers, including the lymphoid cell antigens CD3, CD20 and CD45, von Willebrandt factor, carcinoembryonic antigen and the carcinoma antigen-125 (CA-125). In addition, the FbEM-1 cells were found to be moderately positive for periodic acid Schiff's (PAS) solution but were negative for alpha-naphthyl acetate esterase, peroxidase and chloroacetate esterase activities. Using specific antibodies against the progesterone, androgen and oestrogen receptors, approximately 40% and 5-10% of the cells immunostained for progesterone and androgen receptors respectively, while oestrogen receptors were not detected. On cytogenetic analysis using R-banding, these cells showed numerous chromosomal aberrations, including loss of one chromosome X, 4q+, 5q+, trisomy 7,8 and 10 and tetrasomy of chromosomes 17, 18, 19 and 20. These data show that the continuously growing FbEM-1 cell line established from endometriotic implants may be useful in achieving better understanding of the histogenesis of endometriosis.

Animals↗