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Biomedical subjects

M Camey

Publications and source records attributed to M Camey.

At least 19 recordsLinked to original sources

Update on the Camey II procedure.

Between January 1987 and January 1991, 110 detubularized U-shaped ileocystoplasties (Camey II) following radical cystectomy were carried out in our Department of Urology (CMC Foch Suresnes, France). Our first evaluation of this procedure was carried out in 1989 and reviewed initial 57 patients operated on. These data were compared with those of the Camey I operation. The improvement in neobladder capacity as well as nighttime urinary control achieved by the detubularization required in the Camey II operation was obvious. In this article we review the first 110 patients treated by Camey II bladder replacement following cystectomy.

Cystectomy↗

[T1 G3 bladder tumors: the respective role of BCG and cystectomy].

Forty eight patients with T1 G3 bladder cancer were treated between 1975 and 1991. An associated carcinoma in situ in one third of cases. Twenty six patients received intravesical BCG instillations (an average of 2.5 courses of 6 instillations) with no local recurrence or metastases in 50% of cases (mean follow-up: 54 months). Thirteen patients developed recurrence after a mean disease-free interval of 8 months (range: 3 to 18 months: 7 with disease progression, 5 at an identical stage and 1 Ta. Six cystectomies were performed in this group over the following two years: 3 patients were cured with a mean follow-up of 33 months, 2 died from their cancer, 1 patient is alive with an urethral redux. In view of age and/or clinical context, 7 patients were treated by repeated resections and other local treatments: 3 relapsed without progression, 2 died from their cancer and 2 have been lost to follow-up. Twenty one cystectomies were performed as first-line treatment: 20 patients are recurrence-free with a mean follow-up of 47 months and one patient died from cancer within 6 months. T1 G3 bladder cancer should be considered to be a lesion with a poor prognosis, requiring active treatment. First-line BCG therapy is effective in 50% of cases, but cystectomy is required in the absence of response to BCG.

Adult↗

[The future of total substitution ileoplasty].

Up to now radical cystectomy with or without ancillary methods (radiotherapy, chemotherapy) has been usually considered as the most efficient treatment for invasive bladder cancer. Bladder replacement, which maintains body image, made this mutilation more acceptable for the patient and more easily offered for early stages T1b, T2. According to the progresses of oncologic knowledge, chemotherapy, immunotherapy, it seems reasonable to think that within less than 10 years, conservative treatments for bladder cancer will probably make obsolete radical cystectomy and, of course, associated bladder replacement. Nevertheless, bladder substitution must remain available as a second treatment of choice for some cases and also for bladder deteriorations secondary to trauma, neurologic or benign diseases.

Cystectomy↗

[Fibrous polyps of the urinary tract].

The authors report five cases of fibrous polyps of the urinary tract, which is a rare disease, as Mazeman only reported 12 cases in his review in 1972. These cases confirm the polymorphic nature of the clinical presentation and the site of these tumours of mesodermal origin, essentially composed of richly vascular connective tissue covered with surface epithelium. Treatment is surgical and conservative. The authors performed two junctional resections, one ureterotomy, one ureteroscopic resection and one nephro-ureterectomy for a partially destroyed kidney.

Adolescent↗

[Inhibition of bacterial adherence by nitroxoline on cellular adhesion and on urinary catheter surfaces].

Nitroxolin or 5-nitro-8-hydroxyquinoline, used in the treatment of acute or recurrent uncomplicated urinary tract infection (UTI), has been investigated to demonstrate inhibitory effect on bacterial adherence to epithelial cells or solid surfaces. Nitroxolin in vitro and in urine inhibits bacterial adherence of E. coli 38 (MS/MS) on HeLa cells and epithelial cells from human bladder mucosa. In the same conditions, norfloxacin has no effect. Nitroxolin (MIC/8) decreases with a statistically significant difference (p less than 0.001) the bacterial attachment to a urinary catheter surface made in siliconated latex. These results justify the performance of a clinical trial in the prophylaxis of recurrent UTI and the outcome of a bacteriuria associated with indwelling or intermittent bladder catheter.

Anti-Infective Agents, Urinary↗

Complications of the Camey procedure.

Since the authors' first case in 1958, 221 bladder replacements in more than 500 radical cystectomies have been performed in their department. They discuss perioperative complications; postoperative complications including mortality, gastrointestinal problems, urologic problems, and infections; and late complications such as ileal bladder problems, upper urinary tract problems, secondary diversions, and incontinence.

Humans↗

An original antireflux ureteroileal implantation technique: long-term followup.

An original ureteroileal reimplantation technique in which the ureter is placed in a sulcus created in the ileal mucosa was performed on 51 patients (97 ureters). Followup ranged from 3 to 8 years. As determined by excretory urography, retrograde ileography and urine bacteriology studies the method was effective in 85 per cent of the patients, with a low rate of stenosis (1.5 per cent). The use of this technique, initially limited to patients with the U-shaped continent ileal bladder, has been broadened to include those who undergo various reconstructive or urinary diversion procedures that require ureteroileal reimplantation.

Adult↗