Biomedical subjects

M Cabaret

Publications and source records attributed to M Cabaret.

26 records · Page 2Linked to original sources

PubMed1990

[Correlation of thalamic aphasia and cerebral blood flow].

Relations between linguistic deficits and cerebral blood flow (CBF) were studied in 20 cases of thalamic aphasia due to hemorrhage. Language analysis was based on BDAE, verbal intelligence quotient and verbal subtest of the memory quotient (Wechsler). CBF analysis (and of asymmetry index: AI) was done with 133 Xenon by SPECT technique in tomographic slices and in 15 areas of interest, i.e. cortical and deep areas. Relationships were analyzed by multiple correlations procedure and stepwise regression. Significant correlations were observed between linguistic results and AI of cortical but also deep areas (lenticular). Dynamic anomalies (fluency) were correlated with the IA and/or CBF of the frontal cortex. Verbal comprehension, naming and paraphasia were related to the AI of deep structures (insula and lenticular nucleus) and the AI of posterior cortex (temporo-occipital). Several correlations were found significant between results on verbal IQ of the WAIS and IA of the insula and lenticular nucleus.

Aged↗

PubMed1990

[Clinical course after surgery of aneurysms of the anterior communicating artery].

The evolution and correlations between initial state and outcome (one year) are analysed in 81 patients with anterior cerebral artery aneurysm. The age and initial evaluations are seldomly correlated with late evaluations, Jennett and Holbook scales, frontal syndrome, amnesia. The evaluations at one month are very significantly correlated to the late evaluations.

Adolescent↗

PubMed1986

[Evaluation of the amnesia caused by restricted thalamic infarcts--6 cases].

The amnesic syndrome is analysed in 6 infarctions restricted to the thalamic area. Bilateral lesions were linked to more definite deficits; the anterograde forgetting was unequivocal at the initial stage and affected both verbal and visual memory. In unilateral lesions, deficits were far more discrete and there was no evidence enough for assuming a strict hemispheric specialisation, left for verbal memory, and right for visual memory. These cases and others from the literature suggested that amnesia is more important and pure in infarctions of the anterior part of the thalamus.

Adult↗

PubMed1984

[Post-traumatic retrograde amnesia].

A case of post traumatic retrograde amnesia is described. The patient presented after an initial coma a global amnesia, but the fixation deficit rapidly disappeared, and a severe retrograde amnesia dating back to childhood experience and learning remained the main symptom. Amnesia for remote events was associated with didactic memory deficit and, at a lesser degree, with a verbal memory deficit. Recovery of fixation allowed a progressive relearning. This pattern of impairment was recently related to mesencephalic lesions, but we think that the role of temporal lobe involvement cannot be neglected.

Adult↗

PubMedDate not supplied

[Amnesia in thalamic infarction].

Restricted thalamic infarctions are in man a useful model for investigating the consequences of limited diencephalic lesions on memory and verbal or visual learning. Two new cases of amnesia with thalamo-sub-thalamic infarctions are presented, with a general review of the problem. The gathering of the different cases according to the vascular thalamic territories and, as a consequence, to nuclear or associative structures concerned, allows a better approach of the relations between amnesia and infarctions. Uni or bilateral anterior lesions are the cause of more important and pure memory deficits, posterior infarctions are more often associated to language involvement or spatial cognitive problems which interfere with memorizing.

Adult↗

PubMedDate not supplied

[Acute amnesia caused by a hematoma of the 3d ventricle and the fornix].

An acute amnesic syndrome accompanied the development of a hematoma of the upper part of the third ventricle affecting the fornix. The initial deficit was substantial with corresponding forgetfulness, but there was no false recognition nor fabulation. Recollection of past events was fairly well conserved, subject to difficulties with the temporal structuring of memories. Secondarily. psychometric tests showed preferential impairment of spontaneous recollection and logical learning. The role of lesions of the upper fornix projecting onto the dorsomedian nuclei of the thalamus is discussed.

Acute Disease↗

PubMedDate not supplied

[Psychometric study in Huntington disease].

Thirty-two patients suffering from Huntington's disease (HD) were tested with a short neuropsychological tests battery in order to make a global evaluation of their cognitive functions, and to ascertain whether the tests would be sensitive enough, even in the first stages of the disease, and whatever the individual neuropsychological profile, to be, possibly, an assessment tool for treatment efficacy. Nineteen HD presented with a "mild" form of the disease [stage I and II of Shoulson and Fahn (1979)], 7 men and 12 women, with a duration of illness of nearly 5 years and 13 HD presented with a "moderate" form (stage III and IV), 5 men and 8 women, with a duration of illness of nearly 8 years. These 2 groups had a comparable age at the assessment time (nearly 47) and did not differ, significantly, for the age at onset (39 and 43 respectively), duration of illness or psychiatric disorders. Each test result was reduced to its number of standard-deviations apart the normal mean-value for the same sex, age and study level group.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗

PubMedDate not supplied

[Dysexecutive syndrome and disorders of motor control in prefrontal mediobasal and cingulate lesions].

Disorders of executive function and motor control are considered to be classical consequences of prefrontal lesions. The aim of this study was to investigate these disorders and their evolution in a series of patients presenting with prefrontal and cingulate lesion following rupture of an anterior communicating artery aneurysm. Twenty one subjects were included, and assessed in the secondary and late post stroke phases. We have used the following tests to assess planning and/or execution time and performance: Trail Making test, Wisconsin Card Sorting Test, London Tower Test, Shopping Test of Martin, sequential gestual test and contradictory responses test from Luria. Correlations between these parameters were used to evaluate subjects strategy. In evaluation of execution time, patients were slower than controls, and the difference was more marked using the Trail Making Test (p < 0.01) and the London Tower Test (p < 0.01). Furthermore, the initiation time was increased in the London Tower Test (p < 0.01), this suggesting that they were slower than impulsive. Groups analysis showed that their performance level was most often similar to that of of controls, even in the secondary phase, with the exception of the number of problems solved whatever number of moves in the London Tower test (p < 0.01) and of the percentage of errors in the sequential motor task (p < 0.03). Similar results were observed in the evaluation of single cases. Correlations between execution time and performance were most often significant and negative, in patients and controls. These results suggest that the management of the speed-accuracy compromise was relatively similar, and that impulsivity, which associates reduction of time to poor performance, was absent or mild. Cingulate, and caudate lesions were identified as the source of most cognitive disorders.

Adult↗