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Biomedical subjects

M C Ziemianski

Publications and source records attributed to M C Ziemianski.

10 recordsLinked to original sources
PubMed1989

Macular changes after retinal detachment surgery.

We studied 175 eyes of 175 patients who had successful repair of primary rhegmatogenous retinal detachment. Patients were randomly assigned to be treated with cryotherapy and episcleral sponges or with diathermy, scleral dissection, and encircling silicone bands. Fundus photography and fluorescein angiography were performed six weeks after successful reattachment surgery. Macular complications were discovered in 48 (27%) of the 175 eyes. The most frequent changes were cystoid macular edema in 28 (16%) and preretinal macular membrane in 13 eyes (8%). No significant differences in the incidence of cystoid macular edema were observed between diathermy and cryotherapy. Macular detachment, increased duration of macular detachment, cryotherapy, and pseudophakia were identified as risk factors for certain macular complications.

Adolescent↗
PubMed1982

A comparative study of argon and krypton laser. Photocoagulation in the treatment of presumed ocular histoplasmosis syndrome.

Ninety eyes from 88 patients with active macular subretinal neovascular membranes of presumed ocular histoplasmosis were treated with photocoagulation: 45 eyes with blue-green argon laser and 45 with red krypton laser. Final visual results are compared between these two series and natural course of the disease. The krypton laser photocoagulated eyes obtained better final visual results when compared with both the argon laser treated series and natural course.

Adult↗
PubMed1981

Management of acute ocular histoplasmosis syndrome.

In summary, there are various factors which play an important prognostic role in the final visual acuity of patients with active histoplasma maculopathy. The factors over which we have no control is the location of the neovascular membrane in this maculopathy. The factors over which we do have control are how and when to treat it. We feel that laser photocoagulation is an effective method of treatment. It has been possible to obliterate the NVM as close as 200 micrometers from the foveola, thus preventing the development of subfoveal NVMs which have such a poor visual prognosis. The most important factor is the early treatment with laser photocoagulation. If we could treat all patients within 4 weeks of initial visual symptoms (group A), we might be able to eliminate a large number of patients (group C) who have a much poorer visual prognosis. Serial postoperative fluorescein studies are necessary to detect recurrent neovascular membranes which require further treatment.

Argon↗
PubMed1980

Ophthalmomyiasis interna.

A 15-year-old boy was seen initially with decreased vision in his left eye. Ophthalmoscopic examination showed numerous pigmented subretinal tracts with traction lines radiating to the fovea. Peripheral examination disclosed a maggot in the superior nasal quadrant of the vitreous. There was a hemorrhage emerging from the exit wound in the retina. Removal of the maggot was not indicated because there was no inflammation.

Adolescent↗
PubMed1980

Lymphoma of the vitreous associated with renal transplantation and immunosuppressive therapy.

A renal transplant patient presented with a uveitis unresponsive to high doses of steroids. A pars plana vitrectomy was performed for diagnosis. Light and transmission electron microscopy confirmed the diagnosis of lymphoma of the vitreous. Six percent of the renal transplant recipients develop tumors. This frequency is 100 times greater than the general population. Reticulum cell sarcoma is the predominant type being 350 times more common in renal transplant recipients than in the general population. The patient was taking immunosuppressive drugs which depress the immunologic surveillance. Antigenic neoplastic cells may arise by somatic mutations and may proliferate producing neoplasms with loss of the surveillance mechanism. The case presented illustrates that persons immunosuppressed may develop an eye tumor presenting as uveitis.

Adult↗
PubMed1980

Natural history of vitreous hemorrhage in diabetic retinopathy.

Eighty-five eyes with severe vitreous hemorrhage on initial visit were followed for three to ten years without treatment. A comparison of initial and final visual acuities showed vision to have worsened in 36 eyes (42%), improved in 25 eyes (30%) and remained unchanged in 24 eyes (28%). Vision in 60 eyes was 5/200 or worse when last examined. Of 42 eyes followed three to six years (group 1), the low vision in 24 eyes (57%) was due to vitreous hemorrhage, while of 18 eyes that were followed seven to ten years (group 2), six (33%) had low vision due to vitreous hemorrhage. Traction detachments were found in five eyes (28%) in group 2 as compared with three (7%) in group 1. The prognosis for clearing of the hemorrhage was better when the fundus reflex was brighter and the retina adjacent to the ora serrata was visible. Clearing occurred sooner when the hemorrhage was retrohyaloid rather than in the vitreous gel. The study showed that ultimately 68% of the eyes had a visual acuity of 5/200 or worse.

Cataract↗
PubMed1979

HLA-B7 in presumed ocular histoplasmosis maculopathy.

Sixty-four patients that fulfill the clinical criteria of the presumed ocular histoplasmosis syndrome were typed for common histocompatibility antigens. The clinical criteria included the presence of multiple peripheral punched out choroidal atropic scars, a clear vitreous, and compatible macular disciform lesions in at least one eye. Thirty-four patients were found to have HLA-B7, which is statistically significant at the p less than 0.005 level when compared to a normal population. Though this is statistically significant, other factors must be involved, as there still remain many patients with this clinical picture who do not demonstrate a common histocompatibility antigen.

Gene Frequency↗