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Biomedical subjects

M C Wanscher

Publications and source records attributed to M C Wanscher.

8 recordsLinked to original sources

[Cardiogenic shock in acute myocardial infarction. Time for a more aggressive therapeutic strategy?].

Cardiogenic shock following acute myocardial infarction results in the death of most affected individuals. Longitudinal data suggest that in spite of modern pharmacological inotropic support and thrombolytic regimes, survival from cardiogenic shock has not improved during the last several decades. However, recent observational and limited randomized trial data indicate that some of these high risk patients may derive particular benefit from aggressive percutaneous or surgical revascularisation procedures. This review analyses currently available treatment strategies which appear to hold promise for the future.

Cardiac Surgical Procedures↗

[Nitrogen oxide inhalation in critically ill patients].

Inhaled nitric oxide (iNO) has been extensively used in the treatment of severe hypoxaemic respiratory failure and/or pulmonary hypertension. Although the majority of studies have almost consistently demonstrated a beneficial effect on oxygenation and a reduction in pulmonary artery pressures, none of the randomised trials have reported a reduced mortality using iNO on patients with severe respiratory failure. In neonates with severe respiratory failure and pulmonary hypertension, however, iNO can reduce the need of extracorporal membrane oxygenation. Prior to using iNO on adult patients we suggest other measures to be taken (i.e. optimising ventilator settings, ventilation in prone position).

Administration, Inhalation↗

[Postspinal headache. Is 24-hour flat bedrest a preventive measure?].

Spinal anaesthesia was performed with a 22-gauge needle on 112 consecutive patients above fifty years of age admitted for transurethral surgery. Patients were randomly allocated to either 24 h of recumbency (group A) or ambulation as soon as the spinal had worn off (group B). Postspinal headache was found in 14% of the patients in the recumbency group and in 11% of the patients in the group of early ambulation. There were no differences between the groups regarding incidence, time of onset and duration of postspinal headache. Based on the literature and the present investigation, early ambulation is therefore recommended.

Anesthesia, Spinal↗