Preventing preterm labor. Is terbutaline our best option?
Explore the source record for details and available documents.
Drug Monitoring↗
Biomedical subjects
M C Sisson
Publications and source records attributed to M C Sisson.
Pharmacologic therapy for pregnancy-induced hypertension.
Complications of pregnancy-induced hypertension (PIH) remain a leading cause of maternal mortality in the United States. The etiology of the disease is not fully understood, but pathologic effects of PIH on maternal organ systems are well documented. Present strategies for management emphasize prevention and control of eclamptic seizure and hypertensive crisis and correction of fluid imbalance. The article reviews current trends in drug therapy for the acute management of PIH. Topics discussed include evaluation of magnesium sulfate as an anticonvulsant, hydralazine versus labetalol for management of hypertension, and the role of colloid osmotic pressure in fluid therapy.
Anticonvulsants↗
Strategies for establishing a critical care obstetric service.
Critical care obstetrics is gaining increased recognition as a subspecialty of perinatal medicine. As the specialty continues to expand, many institutions may consider establishing a critical care obstetric service. However, implementing such a service is not feasible for every institution because of space limitations, budgetary constraints, lack of necessary resources, and/or a limited number of critically ill obstetric patients. This article explores strategies for examining the feasibility of establishing a critical care obstetric service, suggests methods of implementation, and offers an alternative when establishing a critical care obstetric service is not feasible.
Feasibility Studies↗
Critical care obstetrics: experts' round table discussion.
A panel of leading experts in critical care obstetric (CCOB) nursing met to discuss the specialty and its future, the impact of changes in the health care system, educational opportunities to learn and update CCOB nursing, formation and use of standards for the specialty, patient placement (dedicated obstetric intensive care units [OB ICU], labor and delivery intensive care units [L & D ICU], regular intensive care units [ICU]), patient populations, and interactions and working relationships with the physicians who care for CCOB patients (perinatologists, obstetricians, internists, obstetric medicine specialists, anesthesiologists, other subspecialists). The topics for discussion were chosen by Carol J. Harvey, RNC, MS, who acted as moderator and Mary Ellen Burke, RN, MS, coordinated the publication of the discussion.
Critical Care↗
Amniotic fluid embolism.
Pulmonary embolism is the leading cause of maternal death in the United States. Amniotic fluid embolism (AFE) represents the least preventable and most lethal of complications with a reported mortality of 86% and an associated fetal demise of 50%. Although it is widely accepted as a clinical entity, AFE is incompletely understood. A combination of clinical presentation, laboratory findings, and exclusion of other pathologies leads to the diagnosis of AFE. The mainstays of treatment are oxygenation, maintenance of cardiac output, and correction of coagulopathy. The prognosis for the patient experiencing AFE remains bleak because it is largely unpredictable and, except for supportive measures, cannot be corrected.
Adult↗
Amniotic fluid embolism.
Pulmonary embolism is the leading cause of maternal death in the United States. Amniotic fluid embolism (AFE) represents the least preventable and most lethal of complications. AFE has a reported mortality of 86% and an associated fetal demise of 50%. AFE is widely accepted as a clinical entity but is not completely understood. A combination of clinical presentation, laboratory findings, and exclusion of other abnormalities leads to the diagnosis of AFE. The mainstays of treatment are oxygenation, maintenance of cardiac output, and correction of coagulopathy. The prognosis for the patient experiencing AFE remains bleak because the course of the disorder is largely unpredictable, and AFE cannot be corrected. Only supportive measures can be given.
Adult↗