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Biomedical subjects

M C Peters

Publications and source records attributed to M C Peters.

49 records · Page 3Linked to original sources

Failure stress criteria for composite resin.

In previous work (Peters and Poort, 1983), the stress distribution in axisymmetric models of restored teeth was analyzed by finite element analysis (FEA). To compare the tri-axial stress state at different sites, they calculated the Von Mises equivalent stress and used it as an indication for weak sites. However, the use of Von Mises' theory for material failure requires that the compressive and tensile strengths be equal, whereas for composite resin the compressive strength values are, on the average, eight times larger than the tensile strength values. The objective of this study was to investigate the applicability of a modified Von Mises and the Drücker-Prager criterion to describe mechanical failure of composite resin. In these criteria, the difference between compressive and tensile strength is accounted for. The stress criteria applied to an uni-axial tensile stress state are compared with those applied to a tri-axial tensile stress state. The uni-axial state is obtained in a Rectangular Bar (RB) specimen and the tri-axial state in a Single-edge Notched Bend (SENB) specimen with a chevron notch at midspan. Both types of specimens, made of light-cured composite, were fractured in a three-point bend test. The size of the specimens was limited to 16 mm x 2 mm x 2 mm (span, 12 mm). Load-deflection curves were recorded and used for linear elastic FEA. The results showed that the Drücker-Prager criterion is a more suitable criterion for describing failure of composite resins due to multi-axial stress states than are the Von Mises criterion and the modified Von Mises criterion.

Composite Resins↗

Cohesive and adhesive fracture patterns of the composite-enamel bond.

A method was developed to adhere composite to a small (1 mm2) surface of human enamel. The geometrical configuration resulted in a complex stress distribution in the vicinity of the composite-enamel bond during fracture in a tension test. The fracture surfaces were examined by scanning electron microscopy. The observed fracture areas at the enamel showed cohesive (composite-composite) as well as adhesive (composite-enamel) parts. The adhesive part of the fracture surface was surrounded by a composite wall. The typical fracture pattern can be explained by the complex stress situation and the deviant structure of the composite near the edge.

Adhesiveness↗

The influence of restorative dental materials on heat transmission in human teeth.

Using the finite element method, we analyzed the temperature distribution and heat flow patterns in an axisymmetric tooth model. The models of an unrestored tooth and three teeth restored with different restorative materials were evaluated comparatively. The insulating ability of a calcium hydroxide cement base (Ca(OH)2) is low, which is inherent in its insufficient thermal and poor mechanical properties. In the given conditions, the Ca(OH)2 base reduces the temperature increase at the cement-dentin interface by 12.5% with respect to a restoration of amalgam only. By using a double base (Ca(OH)2 + polymer-modified zinc oxide-eugenol), the reduction is 21.9%. With respect to a sound tooth model, the presence of a double base in the restored tooth caused a temperature increase of only 0.1 degree C at the pulpo-dentinal junction. The thermal conductivity coefficient (lambda) of amalgam does not have any influence on the results of the calculations. The heat transfer coefficient (alpha) turned out to be an essential parameter in this mathematical model.

Calcium Hydroxide↗

The influence of modification of cavity design on distribution of stresses in a restored molar.

In this study, two different cavity designs were compared from a mechanical point of view: (a) an axisymmetric model of a conventional class 1 cavity preparation and restoration; and (b) an axisymmetric model of a modified cavity design. The modified design was characterized by a cavo-surface angle (c.s.a.) of approximately 90 degrees and a stepped cavity wall. Using a mathematical model, stresses were calculated by finite element analysis to compare the force distribution. It is concluded that the clinical superiority of the modified cavity design, with respect to the marginal breakdown of the amalgam restoration, can be supported by stress calculations.

Dental Cavity Preparation↗

Surface temperature of oral tissues. A review.

The storage of heat in the human body is regulated by a meticulous physiological control of heat production and heat loss. The heat regulation of the dentition and in particular of the pulp tissue is still disputed. Several methods have been used for measuring the surface temperature of the oral tissues. Until now a thermocouple seems to have been the easiest instrument to use for this purpose. Although there is a lack of information about environmental and testing conditions, an approximation of the surface temperatures of the dentition (30-35 degrees C) and soft tissues (32-37 degrees C) has been made based on a literature review.

Body Temperature Regulation↗

A comparison of photoelastic and finite element stress analysis in restored tooth structures.

Two methods for determining internal stresses in tooth structures were compared under a specific load condition. The numerical method of the finite element method has a definite number of advantages over the experimental photoelastic method. The numerical results obtained by the first method are in reasonable conformity with those obtained by the latter. In addition the sensitivity of the finite element method towards variation of a number of relevant parameters has been studied.

Dental Restoration, Permanent↗

Stress analysis of a tooth restored with a post and core.

An idealized axisymmetric finite element model of a second premolar restored with a post and core was used to study the distribution and magnitude of stresses as a function of the following parameters: the diameter of the post, the length and the shape of the post, and finally the interface characteristics between post and cement. Emphasis was directed toward the cement layer interposed between the post and the tooth. Bonding between the post and the cement appeared to be the most important parameter to achieve optimal mechanical behavior of the tooth-prosthesis combination.

Crowns↗

Development of technologies aiding large-tissue engineering.

There are many clinical situations in which a large tissue mass is required to replace tissue lost to surgical resection (e.g., mastectomy). It is possible that autologous cell transplantation on biodegradable polymer matrices may provide a new therapy to engineer large tissue which can be used to treat these patients. A number of challenges must be met to engineer a large soft tissue mass. These include the design of (1) a structural framework to maintain a space for tissue development, (2) a space-filling matrix which provides for localization of transplanted cells, and (3) a strategy to enhance vascularization of the forming tissue. In this paper we provide an overview of several technologies which are under development to address these issues. Specifically, support matrices to maintain a space for tissue development have been fabricated from polymers of lactide and glycolide. The ability of these structures to resist compressive forces was regulated by the ratio of lactide to glycolide in the polymer. Smooth muscle cell seeding onto polyglycolide fiber-based matrices has been optimized to allow formation of new tissues in vitro and in vivo. Finally, polymer microsphere drug delivery technology is being developed to release vascular endothelial growth factor (VEGF), a potent angiogenic molecule, at the site of tissue formation. This strategy, which combines several different technologies, may ultimately allow for the engineering of large soft tissues.

Animals↗

Controlled growth factor release from synthetic extracellular matrices.

Polymeric matrices can be used to grow new tissues and organs, and the delivery of growth factors from these matrices is one method to regenerate tissues. A problem with engineering tissues that exist in a mechanically dynamic environment, such as bone, muscle and blood vessels, is that most drug delivery systems have been designed to operate under static conditions. We thought that polymeric matrices, which release growth factors in response to mechanical signals, might provide a new approach to guide tissue formation in mechanically stressed environments. Critical design features for this type of system include the ability to undergo repeated deformation, and a reversible binding of the protein growth factors to polymeric matrices to allow for responses to repeated stimuli. Here we report a model delivery system that can respond to mechanical signalling and upregulate the release of a growth factor to promote blood vessel formation. This approach may find a number of applications, including regeneration and engineering of new tissues and more general drug-delivery applications.

Alginates↗