Search PubMed⌕ Search

Biomedical subjects

M C Kincaid

Publications and source records attributed to M C Kincaid.

68 records · Page 4Linked to original sources
PubMed1982

A clinicopathological case report of retinopathy of pancreatitis.

A 32-year-old black woman with pancreatitis developed visual loss in both eyes. On ophthalmoscopic examination she had extensive ischaemic infarcts at the posterior poles of both eyes, a clinical picture which has been reported previously in patients with pancreatitis and noted to be similar to Purtscher's retinopathy. On histopathological examination of the eyes after death there were arteriolar occlusions in both the choroid and retina and inner ischaemic infarctions with inner retinal oedema. Owing to the 23-day interval from arteriolar occlusion until death the exact nature of the original occlusion could not be determined. However, either fat emboli or activated complement C5-induced granulocyte embolus formation are possible causes.

Adult↗
PubMed1982

Granulomatous reaction to Choyce style intraocular lens.

Despite the large number of intraocular lens implants performed since Ridley first devised the procedure, there have been few reports of postmortem examination in clinically successful cases. We report a patient who tolerated his Choyce Mark VIII style implant well, despite a three-month episode of mild nongranulomatous uveitis occurring two months postoperatively, until his death 17 months later. This is the sixth postmortem study of an anterior chamber IOL and the only one in which there was a conspicuous granulomatous reaction on the anterior iris surface, with large foreign body giant cells. Despite the presence of a foreign body, the previous eyes that have clinically tolerated implants well and have come to postmortem examination have shown remarkably little inflammation; none have shown this degree of granulomatous reaction previously.

Eye↗
PubMed1981

Iododerma of the conjunctiva and skin.

A 60-year-old white woman developed lesions of the conjunctiva and skin consistent with iododerma. Excision and examination of one of the skin lesions and the conjunctival lesion disclosed pseudoepitheliomatous hyperplasia associated with acute and chronic inflammation. The remaining lesions disappeared with cessation of iodide. We review the clinical and histopathologic features of the halodermas and discuss the ocular manifestations of iodide hypersensitivity. Recognition may require exceedingly careful testing, but such care is necessary because fatal cases of iododerma have occurred.

Conjunctiva↗
PubMed1981

Pars planitis.

We have studied seven eyes from six patients with longstanding pars planitis. Two eyes were phthisical. The remaining five eyes from four patients showed similar findings and included retinal phlebitis, disc and macular oedema, and the presence of a 'snowbank' over the inferior peripheral retina and pars plana. The snowbank consisted of posteriorly detached and collapsed vitreous in which cellular proliferation from the retina with non-pigmented ciliary epithelium was present. Electron microscopy showed the presence of fibrous astrocytes and collagen in two eyes. Retinal neovascularization extended into the snowbank in one case. We have also studied vitreous and preretinal membranes and a portion of a snowbank obtained by pars plana vitrectomy from two eyes of two young patients with active pars planitis. The snowbank and preretinal membranes contained fibrous astrocytes and new collagen and the vitreous snowballs consisted of granulomatous inflammation.

Adolescent↗
PubMed1981

Uveal effusion syndrome.

Cilio-choroidal effusion is a non-specific reaction seen in numerous clinical conditions. It is important to recognize this condition and distinguish it from a solid tumour. Some eyes with this condition have been mistaken for ring melanoma and have been enucleated. In some instances cilio-choroidal effusion is caused by specific conditions and in others it is associated with systemic diseases such as the Vogt-Koyanagi-Harada and the uveal effusion syndromes. In many cases the cause is not apparent and there are no associated or systemic features. This paper reviews the clinical and histopathological features of cilio-choroidal effusion in general, and the uveal effusion syndrome in particular.

Aged↗
PubMed1979

Acute ocular leukemia.

A 71-year-old woman had a history of recent weight loss and bilateral decreased visual acuity, bilateral serous detachment, and mental depression. Fluorescein angiograms showed a myriad of retinal pigment epithelial leakage points. Despite extensive evaluation, the cause of her weight loss and ocular process remained uncertain until her death, when postmortem examination revealed leukemia infiltrates of many organs, including the choroid. After death, we correlated the clinical signs and fluorescein angiograms with the histopathologic findings. This case shows that choroidal disease may be a symptom of undetected leukemia.

Aged↗
PubMedDate not supplied

Ocular and orbital involvement in leukemia.

Leukemia may involve almost any ocular tissue, by direct infiltration, by hemorrhage, and by ischemic changes. Both acute and chronic leukemia can cause ocular signs, either initially or later in the disease process; the clinical features and pathologic correlations of this involvement are reviewed. Also, various chemotherapeutic agents used to treat leukemia may cause ocular toxicity. Recently, bone marrow transplants have been performed more frequently in an attempt to prolong patient survival; if graft-versus-host disease results, one symptom is dry eyes from alacrima. Superimposed infection due to immunosuppression can occur from the disease itself or from treatment. Recognition by the ophthalmologist of the various ocular signs is important in assessing the course and prognosis of leukemia.

Adolescent↗
PubMedDate not supplied

Invasive squamous cell carcinoma of the conjunctiva presenting as necrotizing scleritis with scleral perforation and uveal prolapse.

A 64-year-old white man presented with necrotizing scleritis with scleral perforation and uveal prolapse. Pathologic examination revealed squamous cell carcinoma of the conjunctiva invading adjacent corneal stroma and ciliary body. Invasive squamous cell carcinoma of the conjunctiva is uncommon, and intraocular invasion has rarely been reported in the literature.

Carcinoma, Squamous Cell↗
PubMedDate not supplied

Angiomatous malformation of the retrolaminar optic nerve.

A vascular abnormality of the optic nerve was found incidentally in two infants whose eyes were enucleated because of the clinical suspicion of retinoblastoma. The lesion consisted of numerous thin-walled vascular channels within pial septa of the retrolaminar optic nerve. Although it is unclear if this angiomatous malformation could disturb vision, the lesion may be more common than can be inferred from the small number of reported cases.

Hemangioma↗
PubMedDate not supplied

A hemorrhagic form of Zone I retinopathy of prematurity.

A premature infant who had vascularized only Zone I developed bilateral progressive hemorrhaging in the posterior poles. Subsequently, vitreous hemorrhages and retinal detachments occurred without any progression through Stages I, II, or III of retinopathy of prematurity. This clinical presentation has not been reported previously. These findings suggest profound underlying abnormalities of funduscopically normal Zone I retinal vasculature. Pathologic findings were consistent with end-stage retinopathy of prematurity.

Eye Enucleation↗