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Biomedical subjects

M C Battigelli

Publications and source records attributed to M C Battigelli.

14 recordsLinked to original sources
PubMed1989

Smoke inhalation.

Two cases of smoke inhalation injury are reported with a brief review of the pertinent literature. The frequency of occurrence, the mortality rate, the clinical course of this common event are discussed with emphasis on the following facts: 1) Pulmonary injury is often associated with skin burns and, conversely, skin burns, particularly when severe, are accompanied by significant effects on pulmonary function; 2) Domestic fires, which account for most of these casualties, may involve complex exposure to a variety of aggressive agents (CO, HCN, NOx, etc.), causing systemic effects; 3) The clinical course of the most severe occurrences characteristically consists of three phases, namely acute pulmonary insufficiency, pulmonary edema and bronchopneumonia, in sequence; 4) The mortality rates of these clinical phases range at or about 50 per cent; 5) Significant laryngeal edema and even pulmonary edema may follow an interval of several hours, during which both subjective and objective evidence of injury may be minimal or unnoticed; and 6) The determination of carboxyhemoglobin levels often helps in gauging the severity of the exposure and related effects of either immediate or delayed appearance.

Aged↗
PubMed1984

The effects of occupational exposure on the respiratory health of West Virginia morticians.

Standardized respiratory disease questionnaires and pulmonary function tests were administered to licensed white male morticians attending an educational program in Morgantown, W.Va. Detailed occupational histories were obtained; included were estimates of the numbers of bodies personally embalmed. The pulmonary function of morticians compared favorably with that of residential populations in Oregon and Michigan. Among morticians, relatively high exposure was not associated with chronic bronchitis or pulmonary function deficits. The results suggest that long-term intermittent exposure to low levels of formaldehyde gas exerts no meaningful chronic effect on respiratory health.

Bronchitis↗
PubMed1977

Effect of chemical defoliation on leaf and bract content in raw cotton.

Chemical defoliants are applied to about 40% of the U.S. Cotton acreage as a harvest-aid practice prior to machine picking. Raw cottons derived from defoliated and nondefoliated fields were examined for content of bract and leaf trash Chemical defoliation lowered, but did not remove, leaf as a major trash component. The content of bract was unaffected by this harvest-aid practice. The histamine content in green leaf trash was 10X that found in nongreen leaf trash.

Byssinosis↗
PubMed1975

Mechanism of respiratory injury by TDI (toluene disocyanate).

The pharmacological action of TDI (toluene-diisocyanate) has been measured in vitro, using peripheral leukocytes of human blood. In this system TDI does not release histamine but it appears to contribute to the action of histamine and other mediators by moderating the beta-adrenergic function. Like propranolol TDI reduces the CAMP (cyclic AMP) stimulation produced by cathecolamines. However it differs from propranolol through its inhibition of the glucagon effect on CAMP (which propranolol does not possess) and also by inhibiting antigenic release of histamine.

Cyanates↗