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Biomedical subjects

M Busch

Publications and source records attributed to M Busch.

At least 163 records · Page 9Linked to original sources
PubMed1979

Multidetector endodosimetry probe with silicon-pn-junction-diodes for in-vivo-dosimetry.

In-vivo-dosimetry is necessary to prevent overdosage during radiation treatment techniques of great risk. New special dosemeter probes with up to five Si-pn-junction-diodes in a silicone tube were developed and tested for endodosimetry. They show high efficiency and good linearity of response, without dose-rate dependence. The steep increase of the sensitivity for low energies causes a phantom depth dependence of response. A low temperature dependence but a large anisotropy of response is found for the tested diodes. These multidetector probes proved to be sufficient for direct reading endodosimetric control of dose and dose-distribution during radiotherapy.

Brachytherapy↗
PubMed1978

[Measurement of the radiation load to bladder and rectum in gynecological brachytherapy with a mobile radiation source (author's transl)].

Measurement of the maximal radiation dose in bladder and rectum in intravaginal radiation therapy using a mobile source (afterloading technique) is only possible integrating with a multichannel dosimeter. For this purpose we apply a 5 mm plastic probe being equipped with five semiconductor dosimeter crystals; the latter are fixed within the probe at equidistances of 2 cm from each other. The dose maximum can be obtained by graphic interpolation using the five different values measured. The dosimeter employed is read immediately and permits observation of the doses delivered to the bladder and rectum during radiation therapy.

Female↗
PubMed1977

[The afterloading system of Essen for the intracavitary radiotherapy (author's transl)].

An afterloading system for the intracavitary radiotherapy is described which works with a unique radiation source of 10 Ci 192Ir moving in steps of 1 cm. The times during which the source stops can be determined at a control panel. By using an intermediate piece of 10 cm, a total course of the source of 20 cm can be obtained. The course of the source can be calculated individually by a computer program. This program even takes into consideration an additional deep therapy if the position of the deep therapy field in the target volume is known. This method allows to adapt the total isodoses very precisely to the course of the tolerance doses.

Female↗
PubMed1977

[Dosage in interstitial therapy with gamma emitters (author's transl)].

In this study a system of dose measurement and dosage in the interstitial is proposed. The radioactivity needed for the individual patient can be calculated by means of a simple formula. The author discu-ses rules for the distribution of the sources, clinical principles and the possibility of a combination with the external deep therapy.

Humans↗
PubMed1977

[Radiotherapy of lymphogranulomatosis--relations between radiomyelitis and oncogenic alteration of the spinal marrow (author's transl)].

The authors compare the results of two methods of the upper and lower system irradiation in case of Hodgkin's disease with respect to the spinal marrow. The frequency of radiomyelitis is opposed to the frequency of Hodgkin-specific alterations of the spinal marrow. 74 patients were submitted to telecobalt irradiations the dosage of which was below the tolerances known for the spinal marrow. Two of them presented a radiomyelitis and two a paraplegia of Hodgkin in the irradiated region. One paraplegia caused by the formation of a tumor developed in a region next to the irradiation field; certainly this region would have been affected by a higher dosed large-field irradiation of the spinal marrow. The application of the large-field methods in 61 patients did not cause any radiomyelitis in spite of doses which were higher than the tolerance doses for the spinal marrow of Franke. Hodgkin- specific infiltrations of the spinal canal were also not observed. The large-field method can also be recommended because it seems to offer a larger therapeutic field between the risks of spinal Hodgkin manifestations and radiomyelitis.

Adult↗
PubMed1975

[The dose-volume factor in radiotherapy. Significance of the focal or tumor volume for the evaluation of radiotherapeutic effect].

The absorbed energy dose, in dependence on the irradiated tissue volume or tumor volume (dose-volume-relations) has great significance for the valuation of radiation injuries and of the prognosis of the disease. The present paper includes an analysis, formal demonstrations and interpretation of these relations. Clinical observations and radiobiological experiments in literature were the basis of the present investigation. The assessment is kept simple, the models derived from it interprete well the clinical findings. Through these models, radiobiological findings and clinical experimental principles are connected. This results in a clear conception of the future development of irradiation planning, and the application technique of radiation. The range of validity of the cited models includes the treated volumes usual in radiotherapy. An extrapolation to the cellulary area or to the whole body may only be made with great reservations.

Humans↗