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Biomedical subjects

M Burke

Publications and source records attributed to M Burke.

At least 109 records · Page 6Linked to original sources
PubMed1995

Music therapy following suctioning: four case studies.

This descriptive study evaluates and compares the effectiveness of music, presented both aurally and vibrotactilely, in reducing agitation and physiological instability following a stress-producing intervention (suctioning) in infants with bronchopulmonary dysplasia. Heart rate, oxygen saturation levels, level of arousal, stressful facial expressions, and autonomic indicators were recorded for each of four preterm infants. All infants experienced a reduction in the level of arousal during the taped music intervention when compared with the control condition. Three infants spent an increased amount of time in a quiet alert state and had improved oxygen saturation levels during the vibrotactile intervention. All infants spent more time sleeping during the taped music condition than without music or with the vibrotactile intervention. Results suggest that music is effective in reducing stress-related behaviors for some infants.

Arousal↗
PubMed1995

Dizziness in the elderly: etiology and treatment.

Dizziness is a common but little understood symptom that is a frequent problem for older adults. As the population of older people seeking primary care increases, practitioners need to be knowledgeable concerning the multiple etiologies of dizziness. This article provides classification and clarification of types of dizziness, discusses the multiple etiological factors that influence the development of dizziness in the elderly, and develops assessment parameters and treatment modalities.

Age Factors↗
PubMed1994

The histopathology of splenic lymphoma with villous lymphocytes.

Whereas the hematologic, immunophenotypic, and molecular characteristics of splenic lymphoma with villous lymphocytes (SLVL) have been well documented, the histologic features of the spleen and lymph nodes remain uncharacterized. We have reviewed the histopathology of the spleen in 37 cases of SLVL and of involved splenic hilar lymph nodes in 6 cases. Tissue immunophenotyping was performed in 24 cases, 6 of which had frozen tissue available, and the results were compared with the membrane immunophenotype of the circulating villous lymphocytes and cells extracted from spleen and lymph nodes. In the spleen, SLVL is characterized by involvement of the white pulp follicles, which may be surrounded or replaced by the lymphoma cells. In the red pulp, the cells form small nodules and infiltrate diffusely with sinusoidal invasion. The cytologic appearance of the neoplastic cells varies from a resemblance to small mantle-zone--like lymphocytes to that of marginal-zone cells and there are scattered blast forms. In involved lymph nodes, the infiltrate again centers on the follicles that are usually replaced, but occasionally show preservation of follicle centers; sinuses are often preserved. The tissue immunophenotype is similar to that of marginal-zone B cells. Membrane immunophenotyping may give different results in some cases and may vary depending on the compartment from which the cells are obtained. SLVL in the peripheral blood is a histologically homogeneous entity identical to the condition previously characterised by histopathologists as splenic marginal-zone lymphoma.

Adult↗
PubMed1994

Intraoperative assessment of nodal status in the selection of patients with breast cancer for axillary clearance.

Axillary node status was assessed by intraoperative contact cytology of four sampled nodes in each of 114 consecutive patients with operable breast cancer treated by wide local excision or mastectomy. At a mean follow-up of 18.7 months, 43 node-positive patients who underwent immediate axillary clearance had two locoregional and six distant recurrences with two deaths; four had arm oedema and one shoulder stiffness. There were no recurrences or arm and shoulder morbidity in 71 node-negative women who had no clearance or radiotherapy. The mean hospital stay was 4.3 days for patients having wide local excision versus 7.2 days for those undergoing excision and axillary clearance (P < 0.001), and 8.9 days for patients receiving a mastectomy versus 9.1 days for those having mastectomy and clearance (P not significant). Selective axillary clearance based on intraoperative contact cytology of four sampled nodes reduces hospital stay in patients treated by wide local excision and may lead to a reduction in arm morbidity without impairing disease control.

Axilla↗
PubMed1994

Circulating autoimmune antibodies may be responsible for implantation failure in in vitro fertilization.

OBJECTIVE: To investigate the role of autoimmune factors as a possible cause for implantation failure as manifested by chemical pregnancy after IVF and ET. DESIGN: Anticardiolipin, anti-double-stranded DNA (dsDNA), antinuclear antibody, lupus anticoagulant, and rheumatoid factor serum levels were examined in patients with chemical pregnancies and in matched controls. SETTING: An IVF unit, university-based IVF program. PATIENTS: The study group included 21 patients who had one or more chemical pregnancies and no deliveries. The control group consisted of 21 patients who had conceived and delivered after IVF-ET treatment, without any history of fetal wastage, matched for age, type and duration of infertility, and number of previous IVF cycles. RESULTS: The incidence of circulating autoimmune antibodies in the study group was 33.3% (7/21). Three patients (14.2%) were positive for anticardiolipin, two (9.5%) were positive for antidsDNA, one (4.7%) for antinuclear factor, and one (4.7%) for rheumatoid factor. Autoimmune antibodies were not detected in any of the control group. CONCLUSION: Autoimmunity may play a role in implantation failure in IVF-ET. Circulating autoimmune antibody screening is therefore recommended after chemical pregnancy.

Adult↗
PubMed1994

Suicide using multiple crossbow arrows.

We report the case of a 44-year-old man who committed suicide using multiple crossbow arrows. The first arrow that he fired went between the left eye and nose and passed into a frontal lobe of the brain with no exit wound. He fired a second arrow that entered the palate and went through the brain but did not exit the skull. To the best of our knowledge, no cases of suicide using multiple crossbow arrows have previously been reported.

Adult↗
PubMed1994

Motor vehicle injury prevention for older adults.

Older adults account for more than 20% of the driving population in the United States today and their numbers are increasing. The risk for traffic injury increases significantly for people over 70 years of age. The reasons for the increase in risk are multiple, complex, and individual. Age alone does not define a person. Certain physical age-related changes, such as decline in visual acuity and a slowed neurological response will influence driving skill. Health practitioners need to recognize the older adult at risk, counsel the patient and family members and plan a program of effective interventions.

Accidents, Traffic↗
PubMed1994

Mutant Escherichia coli arginine repressor proteins that fail to bind L-arginine, yet retain the ability to bind their normal DNA-binding sites.

The Escherichia coli arginine repressor (ArgR) is an L-arginine-dependent DNA-binding protein that controls expression of the arginine biosynthetic genes and is required as an accessory protein in Xer site-specific recombination at cer and related recombination sites in plasmids. Site-directed mutagenesis was used to isolate two mutants of E. coli ArgR that were defective in arginine binding. Results from in vivo and in vitro experiments demonstrate that these mutants still act as repressors and bind their specific DNA sequences in an arginine-independent manner. Both mutants support Xer site-specific recombination at cer. One of the mutant proteins was purified and shown to bind to its DNA target sequences in vitro with different affinity and as a different molecular species to wild-type ArgR.

Amino Acid Sequence↗
PubMed1994

The new frontier for pharmacy automation.

The retail pharmacy industry, long a leader in applying EDI, is preparing to use automation in several new areas. For example, pharmacists will be able to interact electronically with physicians' offices and access clinical information.

Clinical Pharmacy Information Systems↗
PubMed1994

Managed care's EDI challenge.

Because managed care plans have to compare themselves with others in price and quality, they are struggling with the issue of how to capture relevant data. Health maintenance organizations and others are attempting to build a consensus on ways to define, standardize and collect information on patient encounters before the federal government imposes mandates. "There's a revolution in managed care data collection," one HMO executive says.

Ambulatory Care Information Systems↗
PubMed1994

How EDI will redefine materials management.

Supply expenses and the related administrative costs are a big-ticket item for America's hospitals. As a result, more materials managers are investigating the use of EDI to cut overhead costs and minimize the need to keep huge stockpiles of supplies. In fact, some envision a day when the routine ordering of supplies will no longer be necessary. But getting there won't be easy. First, hospitals must make small, incremental steps toward automation. And these steps may be the hardest because they involve creating a new way of doing business.

Computer Communication Networks↗
PubMed1994

EDI clears a path for simplifying workers' comp.

In an effort to cut costs in the paperchoked workers' compensation insurance system, states, insurers, employers and third-party administrators are testing new electronic data interchange applications. Proponents say EDI will not only reduce administrative costs, but also will speed the flow of information so that workers can receive proper care sooner and return to work faster. Two groups are developing standard electronic formats for workers' compensation transactions to simplify the conversion to EDI.

Computer Communication Networks↗
PubMed1994

Building a network on a legacy of teamwork.

The nine hospitals that belong to the Hospital Consortium of Greater Rochester have a long history of working together to control health care costs in this upstate New York community. Now they're focusing on creating an electronic health information network. The project has the support of major local employers, which want to keep unnecessary care to a minimum to reduce costs. Electronic networking also will support longstanding efforts in Rochester to ensure that hospitals don't needlessly duplicate services. And the network will allow providers to more easily draw on a treasure trove of information already stored in clinical data bases.

Community Health Planning↗