Biomedical subjects

M Buikhuisen

Publications and source records attributed to M Buikhuisen.

3 recordsLinked to original sources

PubMed1996

Hyperventilation and panic attacks.

OBJECTIVE: Hyperventilation has been posed as an important symptom-producing mechanism in panic attacks. Some arguments and experimental findings, such as the possibility of inducing panic symptoms by voluntary hyperventilation in panic disorder patients, seem to favor this suggestion. This study was undertaken to clarify the role of hyperventilation in panic disorder. Long-term ambulatory measurement of transcutaneous arterial CO2 pressure (PCO2) offers an opportunity to test directly the co-occurrence of panic and hyperventilation under natural conditions. METHOD: Transcutaneous PCO2 was measured during three to four sessions of approximately 7 hours each in 28 panic disorder patients. Patients were instructed to expose themselves to fear-provoking situations and to press a button as soon as they experienced panic. One-half of the patients experienced one or more panic attacks during these sessions. RESULTS: A decrease in PCO2 was observed during only one of the 24 registered panic attacks that lasted at least 3 minutes. Even during this particular attack, the degree of hyperventilation was not impressive. CONCLUSIONS: These findings indicate that the hypothesis that hyperventilation is an important symptom-producing mechanism in panic may be dismissed.

Adult↗

PubMed1994

Continuous monitoring of panic.

Data on naturally occurring panic attacks were gathered through continuous self-monitoring for 94 patients suffering from panic disorder with agoraphobia. A total of 1276 panic attacks were collected. In this article various aspects of panic attacks, including severity, duration and time of onset and situations in which panic occurs are addressed. In addition, the symptoms of panic were investigated, examining the (in)variability of attacks within each patient and the patterning of symptoms in the entire group of patients. The most important findings were as follows: attacks occurred predominantly in nonphobic situations; nocturnal panic attacks were generally more severe than attacks during the day; symptom patterns across various attacks, stemming from the same patient, were rather variable; and finally, a substantial number of the attacks (40%) did not meet the DSM-III-R criteria for number of symptoms.

Adult↗

PubMed1992

Dissimulation and the sex difference in self-assessed fears: a brief note.

Since the publication of the first findings with a Fear Survey Schedule over five decades ago, there have been no published studies examining the extent of overlap of factorially-derived robust dimensions of irrational fears with social desirability or dissimulation. Due to measurement problems associated with the use of individual fear items or general fear measures, the findings reported to date are relatively meaningless. In the present study, community volunteers were administered the Fear Questionnaire and the Eysenck Personality Questionnaire-Lie scale, the correlation between both measures determined, and the influence of the Lie scores on the sex difference in self-assessed fears examined. Neither in males nor in females were Agoraphobic and Social fears significantly correlated with dissimulation. Significant associations reflecting small effect sizes were obtained in both samples between Blood-injury fears and Lie scores. Only the sex difference in Blood-injury fears was meaningfully affected by dissimulation: the usual finding of higher mean scores for females was obtained only after controlling for the influence of Lie scores. The importance of taking the research and practical implications of the findings with respect to the Blood-injury fears dimension seriously, despite the small magnitudes of the relevant data, was emphasized, as was the need for further studies in this area.

Adolescent↗