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Biomedical subjects

M Briggs

Publications and source records attributed to M Briggs.

At least 181 records · Page 10Linked to original sources
PubMed1972

Withdrawal depression in obese patients after fenfluramine treatment.

Measurements of subjective feeling in 20 patients receiving fenfluramine alternating with placebo and in 19 patients receiving phentermine alternating with placebo indicated that depression of mood occurred four days after fenfluramine withdrawal but no such depression was seen with phentermine.

Adult↗
PubMed1971

Drugs of dependence though not of abuse: fenfluramine and imipramine.

Measures of subjective feeling used by five patients indicated that depression of mood occurred about four days after fenfluramine withdrawal. An experiment in which another 11 patients took fenfluramine 80 mg for 28 days confirmed the depression, maximal on the fourth withdrawal day. It also indicated that in the first week of administration there was some mood elevation, but with feelings of impaired ability to concentrate. The drug reduced appetite and weight. A comparison is drawn with imipramine, which was found to induce initial and withdrawal changes of subjective experience (of dreaming) in six volunteers. It is suggested that certain mood-influencing drugs may not be drugs of abuse because of some unpleasant initial effects, though they can be drugs of dependence.

Adult↗
PubMed1971

Prevention of delayed traumatic facial palsy.

A previous impression that corticotrophin provided prophylaxis against delayed traumatic facial palsy has now been confirmed by the results obtained from the first 50 patients so treated.

Adrenocorticotropic Hormone↗