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Biomedical subjects

M Brett

Publications and source records attributed to M Brett.

42 records · Page 3Linked to original sources

The world distribution of gallstones.

This paper presents two maps summarising all available published data on the world distribution of gallstones as recorded from autopsy studies. It is suggested that further autopsy studies are required, especially in Asia, Russia, the Middle Eastern and Mediterranean countries and South America. Such studies could be readily carried out and would contribute to our understanding of the aetiology of gallstones.

Adolescent↗

Intracellular serum proteins in cerebral gliomas and metastatic tumours: an immunoperoxidase study.

An immunoperoxidase technique was used to compare the presence of serum proteins in tumour cells in twenty cerebral gliomas and four intracerebral metastatic carcinomas, with the serum protein content of reactive astrocytes around four cerebral infarcts. Rabbit antiserum to human immunoglobulins and albumen was applied to paraffin sections of tumour biopsies and of infarcts from postmortem brains. All the reactive astrocytes surrounding infarcts stained positively for immunoglobulins and albumen. In the gliomas, a continuous range of staining was observed in plump astrocytic tumour cells varying from strongly positive to unstained. Very few poorly-differentiated glioma cells stained for serum proteins; metastatic tumour cells, areas of capillary endothelial proliferation, and spindle cells in gliosarcomas remained unstained. These results suggest that the astrocytic function of serum protein uptake from the extracellular fluid is often lost in poorly-differentiated glioma cells, but is retained to a variable degree by those tumour cells which histologically resemble reactive astrocytes.

Adenocarcinoma↗

Transanal endoscopic microsurgery.

Transanal endoscopic microsurgery is a minimally invasive technique for local excision of tumours in the rectum and lower sigmoid colon. It allows precise transanal dissection and suturing, and enables sphincter-preserving local resection to be performed without an abdominal or perineal incision.

Electrocoagulation↗