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Biomedical subjects

M Brandfonbrener

Publications and source records attributed to M Brandfonbrener.

18 recordsLinked to original sources
PubMed1982

Asynchronous ventricular pacing: a rare cause of ventricular tachycardia.

Asynchronous cardiac pacing may induce ventricular tachycardia and fibrillation, particularly in patients with ischemic heart disease and possibly other types of myocardial abnormalities. All patients with implanted asynchronous pacemakers, and those whose demand pacemakers operate in asynchronous mode for any reason, are to be considered at risk from this complication. In patients with serious myocardial abnormalities consistent demand pacing should be assured, even if it requires early pacemaker replacement. Anti-arrhythmic agents may prove useful for temporary suppression of pacemaker-induced arrhythmias.

Aged↗
PubMed1975

Reversible renal concentrating defect in shock.

The loss of renal concentrating power in haemorrhagic shock is reversible upon correction of the shock state. Shock resulting from acute hypovolaemia leads to the following sequence of events: (1) diminished renal blood-flow; (2) decreased superficial cortical nephron perfusion; (3) continued juxtamedullary nephron perfusion; (4) enhanced proximal reabsorption of Na, Cl, and H23; (5) decreased delivery of these ions to the ascending limb, which results in diminished hypertonicity of the medullary interstitium. This hypotonicity is worsened by the "washout" effect on the interstitial hypertonicity caused by continued perfusion of the juxtamedullary vasa recta which results in (6) diminished renal concentrating capacity due to elimination of medullary hypertonicity. Replenishing blood-loss and correcting the hypovolaemic state "regenerates" the hypertonic renal medullary interstitium by (a) diminishing proximal reabsorption and allowing presentation of greater quantities of Na and Cl to the ascending-limb "pump", (b) restoring superficial cortical nephron perfusion, thereby decreasing juxtamedullary perfusion and in this manner eliminating medullary "washout".

Animals↗
PubMed1970

Cardiomyopathy in the Southwest American Indian.

Six Southwestern American Indian patients are reported to have primary myocardial disease or congestive failure of unknown cause. Two are Navajo, three are Laguna, and one is Isleta. Clinical and laboratory features are discussed. This disease appears in culturally traditional Indians and is not associated with contact with American civilization. It occurs in probably adequately nourished Indians in the majority of whom excessive alcohol consumption is not found. No familial cases were noted. This syndrome is probably not uncommon in the American Indian.

Adult↗
PubMed1969

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