Search PubMed⌕ Search

Biomedical subjects

M Brack

Publications and source records attributed to M Brack.

At least 55 records · Page 3Linked to original sources
PubMed1995

Intestinal trichomoniasis due to Tritrichomonas mobilensis in tree shrews (Tupaia belangeri).

Intestinal trichomoniasis was observed in 156 of 202 Tupaia belangeri (77.2%). The parasites were located principally in the cecum (75%) and were far less common in the proximal portion of the colon (19%) or terminal portion of the ileum (6%). Advanced trichomoniasis was associated with liquid cecal contents but not diarrhea. The trichomonads had a tendency to penetrate the mucosal epithelial layer, causing desquamation of entire crypts. They never penetrated the epithelial basement membrane and never triggered inflammatory responses. The trichomonads were characterized by three anterior flagella and one trailing flagellum that extended over the entire parasite body, connected to it by an undulating membrane. The capitulum of the straight axostyle formed a small but well defined pelta, and the stout costa had distinct banding. The parasites thereby matched the description of Tritrichomonas mobilensis.

Animals↗
PubMed1994

Intestinal capillariasis in New World monkeys.

Two cases of intestinal capillariasis have been identified at necropsy in a squirrel monkey and a capuchin monkey born and raised in captivity. The parasites are described as far as possible from the histopathological slides or intestinal contents, and their relationship to other intestinal capillarids, especially those of primates, is discussed.

Animals↗
PubMed1994

Ultrastructural and immunohistochemical studies in callitrichid renal glomeruli.

The "normal" mesangium of callitrichids exhibits certain features pointing to enhanced activity. Protrusions of the mesangial cellular cytoplasm (blebs) into the capillary lumen were observed very frequently as were electron-dense granules in mesangial matrix channels. Histochemical, alpha-actin expression was invariably observed in the mesangial cells of callitrichids.

Actins↗
PubMed1992

In vitro characteristics of Yersinia pseudotuberculosis of nonhuman primate origin.

Six strains of serotypes 1 or 2 of Y. pseudotuberculosis were isolated from dead squirrel monkeys, a cotton-top tamarin and a marmoset hybrid. All strains harboured a 71.6 kb plasmid, all were totally oxacillin-resistant and partially resistant to cephalosporins. Biochemically, serotypes 1 and 2 differed from each other in their beta-galactosidase production in a nonfermenter system, whereas the lack of rhamnose, maltose, salicin and trehalose fermentation seemed to be attributable to technical causes.

Animals↗
PubMed1991

[Yersinia pseudotuberculosis in New World monkeys].

It is reported on four cases of pseudotuberculosis in 2 Saimiri sciureus, 1 Callithrix jacchus/penicillata hybrid and 1 S. oedipus. The animals came from two different groups, one being infected with Y. pseudotuberculosis serotype I, the other with Y. pseudotuberculosis serotype II. All cases showed intestinal infection of thermophile Campylobacter. Remarkable were severe haemorrhagic components and the distinct RHS-proliferation, especially in the mesenteric lymphatic nodes.

Animals↗
PubMed1991

Angioplasty in ulcerative coronary artery disease: acute results and early follow-up.

The safety and efficacy of percutaneous transluminal coronary angioplasty (PTCA) for stenoses involving ulcerative lesions were retrospectively studied. Seventy-seven patients (62 men and 15 women, mean age 62 +/- 10 years) representing 3.4% of 2,250 patients treated with PTCA during the period January 1, 1988 and June 30, 1990, had pre-PTCA stenoses defined as ulcerated. Twenty-eight (36%) of the stenoses were localized in the left anterior descending coronary artery, 9 (12%) in the left circumflex and 40 (52%) in the right coronary artery. During angioplasty, percent diameter stenosis was reduced from 73 +/- 14% to 22 +/- 13% and transstenotic gradient decreased from 48 +/- 18 to 12 +/- 6 mm Hg. Clinical success (freedom from angina at discharge without coronary bypass surgery, infarction or death) was achieved in 70 patients (90.9%). There were seven unsuccessful cases: three underwent elective coronary bypass surgery, one was managed medically, and three developed a major flow interrupting dissection during the procedure requiring emergency coronary bypass surgery. There were no deaths. At mean follow-up of 7.6 months, 45 of 61 patients (73.7%) remained asymptomatic. One patient needed an elective coronary bypass surgery and five patients had a successful repeat PTCA. In conclusion, PTCA for an ulcerated stenosis can be performed safely with a high primary success rate and a favorable early clinical course.

Angioplasty, Balloon, Coronary↗
PubMed1991

Transesophageal echocardiography in patients with mechanical circulatory assistance.

Transesophageal echocardiography was used to assess myocardial function and to detect complications after mechanical circulatory support for 8 patients with cardiogenic shock. In 3 of 8 patients, serial transesophageal echocardiography documented improvement of systolic ventricular function, and it was possible to wean these 3 patients from the ventricular assist device. In all patients, transesophageal echocardiography added clinically important information including the extent of left and right ventricular dysfunction (6 patients), presence of atrial or ventricular thrombus (5 patients), presence of pericardial effusion or clot (2 patients), and verification of the position of the intravascular device (1 patient). Thus, transesophageal echocardiography may provide clinically useful information regarding both the underlying cardiac disease and potential complications from the mechanical circulatory assistance.

Adult↗
PubMed1991

Jugulo-sternal-gland tumors in male tree shrews (Tupaia belangeri).

Adenocarcinomas of the jugulo-sternal glands were observed in seven adult male tree shrews (Tupaia belangeri) at biopsy or necrospy. Five of these tumors were classified as carcinomas of the sebaceous gland compartment; one was diagnosed as a papilliform adenoma of apocrine (monoptychic) sweat glands; and one was of a mixed sebaceous gland/apocrine sweat gland structure. Four sebaceous gland carcinomas had histologic evidence of vascular invasion; one had metastasized to the regional lymph nodes and lungs and had also invaded the thoracic muscles.

Adenocarcinoma↗
PubMed1991

Pachyonychia congenita-like disorder in cotton-top tamarins (Saguinus oedipus oedipus).

A spontaneous genodermatosis in 13 cotton-top tamarins is described as a retrospective study. The disease appeared as alopecia, pigmentary disturbances, and claw dystrophy similar but not identical to human Pachyonychia congenita. The disease in the tamarins seems to be inherited as an autosomal recessive trait, becoming clinically apparent around adolescence. In certain families the neonatal mortality rate was also above average, reaching 100%.

Alopecia↗
PubMed1990

[IgM nephropathy (nephritis) in clawed monkeys (Primates, Anthropoidea, Platyrrhina, Callithricidae)].

A spontaneously occurring IgM-mediated mesangioproliferative nephropathy was detected in 91% of tamarins and marmosets over 6 months old. Intraglomerular IgM deposits could be demonstrated in all animals, usually in a mesangial pattern and in some cases along the glomerular endothelia. The clinical signs were hematuria and proteinuria. The progressive disease remains silent for long periods, but is directly or indirectly related to the death of 10-20% of the affected animals. Morphological characteristics are those of mesangial hyperplasia accompanied by subacute to chronic tubulointerstitial inflammation. The callithrid IgM-nephropathy is compared to similar human immunocomplex nephropathies.

Animals↗