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Biomedical subjects

M Bod

Publications and source records attributed to M Bod.

9 recordsLinked to original sources
PubMed1992

Evaluation of anticonvulsant drugs during pregnancy in a population-based Hungarian study.

The Hungarian Case-Control Surveillance of Congenital Anomalies, from 1980-1987, involved 10,698 malformed cases and 21,546 non-malformed controls. Ninety-five pregnant women were treated by 144 anticonvulsants excluding diazepam and barbiturates. The rate of anticonvulsant use was 2.9 times higher in pregnant women having malformed offspring than in control mothers and this difference was greater in polytherapy than in monotherapy.

Abnormalities, Drug-Induced↗
PubMed1991

Short clinical report: a new case with de novo partial 9p monosomy.

A female patient is described with a karyotype 46,XX,del (9) (p22) showing characteristic dysmorphic phenotype: trigonocephaly, prominent forehead, long philtrum, small mouth, high arched palate, low set ears, short neck, widely spaced nipples, long fingers and toes, omphalocele. The first Hungarian case of 9p monosomy syndrome is reported here.

Abnormalities, Multiple↗
PubMed1983

Incidence at birth of different types of limb reduction abnormalities in Hungary 1975-1977.

Congenital limb reduction abnormalities have been reported in Hungary since 1970. A clinical and genetic study was made of 274 cases reported from 1975 to 1977, corresponding to a total number of 561915 births. A classification according to type of defect, involvement of one or more limbs and other associated defects is attempted. Data on incidence, sex ratio, laterality and mortality are presented.

Abnormalities, Multiple↗
PubMed1983

Family study of congenital limb reduction abnormalities in Hungary 1975-1977.

A family study of 274 index patients with limb reduction malformations born in Hungary from 1975 to 1977 is reported. The majority of 789 first-degree relatives were personally examined. Information was collected on 1094 uncles and aunts and on 1095 cousins, and those affected by limb malformations were examined. Among 789 first-degree relatives six were affected by a similar malformation (radial, ulnar and central ray defects) and 1 by a malformation of a different type; no secondary cases of the same type were found among the relatives of patients with terminal transverse and amniogenic malformations, and with limb malformations which were part of syndromes or unclassifiable associations with other malformations. While a few rare types of limb defects are due to dominant genes, the aetiology of most cases is obscure. There is no evidence of sex-linked inheritance, of multifactorial causation or of environmental factors shared by relatives. These results are similar to those of an earlier study by Birch-Jensen.

Abnormalities, Multiple↗
PubMed1983

An aetiological evaluation of increased occurrence of congenital limb reduction abnormalities in Hungary, 1975-1978.

In Hungary a significant increase occurred in the birth prevalence of congenital limb reduction abnormalities from 1975 to 1978 after the introduction of a new population policy in 1974. A case-control study showed a slight increased use of drugs for ovulation induction, oral contraceptives prior to conception and more frequent extramarital births as well as unwanted pregnancies.

Abnormalities, Drug-Induced↗
PubMed1981

Congenital malformation surveillance.

Records (24,798) of the Hungarian Congenital Malformations Registry for the 728,343 total births in 1973-1976 were examined. A total of 3,116 babies were identified as having a primary congenital abnormality which may be associated with secondary developmental anomalies. Some 842 of these babies had 1,194 additional congenital abnormalities that we consider to be secondary. The exclusion of these secondary abnormalities from birth prevalence figures represents a more accurate registration and evaluation of congenital abnormalities from both statistical and etiological points of view.

Abnormalities, Multiple↗