Radioisotope (gamma) cerebral angiography. Technical note.
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Biomedical subjects
M Blau
Publications and source records attributed to M Blau.
Comparison of four methods of analysis of 99mTc pyrophosphate uptake in rheumatoid arthritic joints.
Knees, hands, forearms and thighs in 22 patients with classical rheumatoid arthritis and 18 controls were imaged with 99mTc pyrophosphate. The uptake of 99Tc pyrophosphate in the joints of the hand and knee was quantitated using a gamma camera interfaced to a computer. Quantitative measurements of joint activity were assessed by analyzing resultant data in a number of ways. Counts per unit area normalized for body weight and dose of radiopharmaceutical was found to be the most satisfactory method of quantitating differences in disease activity. However, the sensitivity of the method was not great enough to clearly distinguish normal and rheumatoid joints.
Arthritis, Rheumatoid↗
Investigation of the metabolic acitivity of bone in rheumatoid arthritis.
Uptake of 99mTc pyrophosphate was measured in the midthird of the radius, ulna femur and metacarpal bones of 22 men with rheumatoid arthritis and 18 control subjects. It was significantly elevated in the rheumatoid population. In a parallel study, the retention of 99mTc methylene diphosphonate was significantly increased in 12 of these rheumatoid patients compared to 6 of the control subjects. These results suggest that there is increased bone turnover occurring in "nonjoint" bone in patients with RA and that the use of such bone as a reference standard for joint imaging is likely to prove misleading.
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