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Biomedical subjects

M Bille

Publications and source records attributed to M Bille.

At least 19 recordsLinked to original sources
PubMed1995

Peritonsillar infiltration with low-dose tenoxicam after tonsillectomy.

We have compared the effect of peritonsillar infiltration with tenoxicam 5 mg and placebo on postoperative pain after tonsillectomy. Fifty patients undergoing bilateral elective tonsillectomy under general anaesthesia were allocated randomly to receive peritonsillar infiltration with tenoxicam 5 mg in 8 ml of normal saline (4 ml per tonsil) or normal saline only, before tracheal extubation. Median time to first request for morphine (30 min in each group, P = 0.83), cumulative morphine requirements from 0 to 2 h after surgery (two and one doses, P = 0.50), and from 2 to 24 h after surgery (one dose in each group, P = 0.17) were similar. There were no significant differences between groups in VAS scores at rest or when drinking 100 ml of water at any time. The power of detecting a reduction in VAS scores of 20 mm was 90% at the 5% significance level.

Adolescent↗
PubMed1994

[Bone-anchored auricular prosthesis].

During the period February 1989-September 1991, 15 patients with absent or defective pinna were treated with a bone-anchored auricular prosthesis at the ENT-department, Rigshospitalet, Copenhagen. These patients were followed up from the hospital records and by means of a questionnaire. Altogether 40 titanium implants have been inserted, of which one implant was found not to be integrated at the time of the second-stage surgery. Five patients underwent additional surgery, one patient because of non-integration of a screw, and four patients on account of soft-tissue reactions. From the questionnaire replies it appears that all patients found the cosmetic result and the technique concerning mounting of the prosthesis very satisfactory. Nearly half the patients found that the care of the skin around the abutments caused considerable problems. Three patients had experienced unintended losses of the prosthesis. In conclusion, treatment with a bone anchored auricular prosthesis has considerable advantages compared to treatment with a prosthesis attached by adhesive. Furthermore the use of a bone-anchored prosthesis should be considered a viable alternative to surgical reconstruction because of the outstanding aesthetic result and because the surgical procedure puts less strain on the patient. The disadvantage of the method is the lifelong daily care of the skin and the dependence on the health services.

Adult↗
PubMed1993

Bonding of enamel-dentin crown fragments after crown fracture. An experimental study using bonding agents.

Previous experimental studies into the use of dentin bonding agents for reattachment of enamel-dentin crown fragments have demonstrated fracture strength about 50-60% of that of intact teeth. In the clinic this has been reflected in the frequent need of repeated bonding of the treated incisors due to refracture. Recently newer bonding agents have been developed which can bond equally well with enamel and dentin. Employing the same experimental model, these bonding agents (All-Bond 2, Scotchbond MP) were used to reattach crown fragments to the remaining portion of sheep incisors. Loading of teeth bonded with these agents in an Instron testing machine at a speed of 1 mm/min demonstrated similar fracture strengths as those previously achieved with Gluma, Scotchbond 2 or Tenure. A second study was carried out whereby fragments were bonded with Scotchbond MP and loaded at various speeds. The results demonstrated that the fracture strength decreased exponentially with increased loading speed. By extrapolation, it was concluded that the strength was nil at a loading speed of approximately 2 m/min. It was concluded that the weak link in the bond between tooth fragment and remaining tooth structure is the bonding resin. Theoretically, a resin which is slightly elastic might act as a shock absorber to withstand functional stress. However, studies carried out with resins of varying moduli of elasticity gave disappointing results probably due to their low flexural strength.(ABSTRACT TRUNCATED AT 250 WORDS)

Analysis of Variance↗
PubMed1981

Serum tryptophan levels in alcoholics.

An oral load of L-tryptophan was administered to alcoholics and non-alcoholic control subjects in order to determine whether prolonged ethanol consumption influences serum tryptophan levels. Both samples were taken under fasting conditions and after the load. No differences in fasting serum tryptophan levels were noted. In alcohol addicts and in alcoholics treated with disulfiram (Antabuse) serum tryptophan levels were below normal after the load. No differences were observed in serum tryptophan levels between treated alcoholics not receiving disulfiram and control subjects. The findings suggest that chronic consumption of ethanol-containing beverages can enhance removal of tryptophan from the blood. Explanations to account for this finding are considered.

Adult↗
PubMed1978

Traffic accidents involving psychiatric patients. Characteristics of accidents involving drivers who have been admitted to Danish psychiatric departments.

A nationwide study of psychiatric in-patients driving motor vehicles and involved in accidents causing bodily injury in the years 1972--74 was undertaken. Compared with drivers in general involved in accidents causing bodily injury, drivers with a psychiatric record were characterized by an over-representation of women. A preponderance of psychiatric drivers in the age group 25--54 was observed. About 3% of drivers with a psychiatric record were involved in two or more accidents during the period studied. A greater proportion of the psychiatrically diseased group drove stolen vehicles, without valid licences, and were found not to have used safety belts at the time of the accident. Occurrence of injury was more frequent among the diseased drivers. They were more frequently alcohol intoxicated and with a higher blood alcohol level. The most commonly encountered diagnostic groups were personality disorder and transitory reactions.

Accidents, Traffic↗
PubMed1977

Traffic accidents involving psychiatric patients. Description of the material and general results.

The present investigation analyzes the characteristics of traffic accidents involving psychiatric patients and comprises all persons who during the period 1970-74 have been admitted to a psychiatric in-patient institution and who during the period 1972-74 have been involved in a traffic accident causing bodily injury. Accidents with psychiatric patients involved constitute about 5.7% of all traffic accidents reported in Denmark. Compared with the total group of accidents, they are characterized by an over-representation of women and of persons in the age group 25-54 years. Accidents with psychiatric patients are over-represented during the period July-September, and in areas densely built up. The accidents tend to be more complicated, and the psychiatric patients are more likely to get injured and be hopitalized due to the accident. The investigation is based exclusively on routinely collected data. The limitations with which the results are encumbered and the problems concerning methodology and comparison of different studies are discussed.

Accidents, Traffic↗