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M Bilitch

Publications and source records attributed to M Bilitch.

At least 19 recordsLinked to original sources

Performance of implantable cardiac rhythm management devices.

Our data represent use, follow-up, and management decisions from eight independently functioning centers and most importantly, actuarial survival of ICRMD's that have been implanted for a sufficient time period to allow assessment of time versus failure. General patterns of possible target durations for adequate performance for present or future generations of similar clinical devices may be suggested by the data that we have presented. However, it would be inappropriate to conclude from these data that any presently implanted ICRMD would have a particular functional reliability. Furthermore, these data only summarized device hardware performance and cannot and must not be used to determine either short-term or long-term individual patient status, management, or outcome.

Electric Countershock

NASPExAM.

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Cardiac Pacing, Artificial

Performance of implantable cardiac rhythm management devices.

Our data represent use, follow-up, and management decisions from seven independently functioning centers and most importantly, actuarial survival of ICRMDs that have been implanted for sufficient time period to allow assessment of time versus failure. General patterns of possible target durations for adequate performance for present or future generations of similar clinical devices may be suggested by the data that we have presented. However, it would be inappropriate to conclude from these data that any presently implanted ICRMD would have a particular functional reliability. These data, furthermore, only summarized device hardware performance and cannot and must not be used to determine either short-term or long-term individual patient status, management, or outcome.

Actuarial Analysis

Ventricular refractory periods in relation to rate and test-site VT intervals in anesthetized and conscious dogs: a canine model for conscious state measurements.

The functional relationship of ventricular effective refractory period (ERP) with basic cycle length (BCL) of stimulated ventricular depolarization and VT intervals of test-site unipolar ventricular electrograms were studied in five conscious and eight anesthetized (sodium pentobarbital, 30 mg/kg) open-chested dogs. The range of BCLs studied was 300 to 1000 ms, achieved through ventricular stimulation following chemically-induced complete AV block. In the conscious animal model developed for this study, two-to-four ventricular electrode leads were exteriorized and the ventricular rate was maintained by an implanted programmable VVI pacemaker. In all animals studied, the BCL-ERP relation was closely represented by the empirical equation ERP = A-B.Exp(-k.BCL), and the VT-ERP relation over the same range of BCLs was linear: ERP = C + D.VT. The correlation coefficients were in the range of 0.991 to 0.999. The mean values of the parameters in the above equations determined by the appropriate non-linear or linear regression analysis showed significant differences between the two groups of animals studied. In three conscious animals a strong linear correlation between the test-site VT intervals and simultaneously measured QT intervals measured from the lead II surface electrogram was demonstrated (r = 0.993 to 0.998). For a fixed site of stimulation, the morphology of ventricular depolarization complexes as well as the corresponding T-waves remained essentially unaltered with BCL for both myocardial and surface electrograms. The possible applications of developed canine model and the results of the present study include: (1) the study of the rate-dependent effects of cardioactive drugs on ventricular electrophysiology and, (2) the improved design of electronic refractory periods of rate programmable pacemakers.

Anesthetics

A digital module for cardiac pacemaker assessment.

The accuracy of a digital pacemaker testing module incorporated into a digital recording electrocardiograph has been tested against two other methods of waveform recording. Measurements of rate (pulse interval), pulse width, pulse amplitude and ratio of trailing edge to the leading edge amplitude were found to be highly accurate. The pulse shapes were faithfully recorded. The practical clinical use of the method is discussed.

Electrocardiography

Fascicular premature beats with narrow QRS in the presence of bundle-branch block.

The electrocardiogram of a sixty-two-year-old male revealed right bundle-branch block, left anterior superior fascicular block, and right precordial Q waves consistent with anteroseptal myocardial infarction. Premature beats with narrow QRS (100 ms) occurred intermittently; coupling intervals varied between 560-600 ms. His bundle electrogram confirmed the fascicular origin of the premature beats. During atrial prematuring studies, it was shown that an appropriately timed premature beat could prolong infra-His conduction time, but QRS normalization was not achieved. The possible electrophysiologic mechanisms that could result in a normal QRS complex with fascicular premature beats in this patient are discussed; a new mechanism is suggested.

Arrhythmias, Cardiac