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Biomedical subjects

M Benaguida

Publications and source records attributed to M Benaguida.

At least 37 records · Page 2Linked to original sources

[Pulmonary edema following laryngospasm in a child].

A case is reported of a pulmonary oedema secondary to a laryngospasm in a 10-year-old child during a scheduled orchidopexy. Anaesthesia was induced with 50% nitrous oxide in oxygen and halothane via a face mask. Pulmonary oedema occurred before the relief of the laryngospasm and its course was uneventful after tracheal intubation and mechanical ventilation with PEEP. Hydrostatic forces or an increased capillary permeability are likely causes of the oedema. The outcome is usually favourable.

Anesthesia, Inhalation↗

[Cerebral complication in eclampsia].

Many brain complications occur during eclampsia with various degree of gravity. The pathogenesis of these lesions continues to be a source of considerable controversy. Five cases of eclampsia with severe neurologic manifestations were treated in our surgical intensive care unit. The CT image appeared to be related to haemorrhagic lesions (3 cases) and ischaemic lesions (2 cases). The clinical course was favourable, often reversible, in cases with oedema and ischaemia maternal prognosis was poor in the case with haemorrhage.

Adolescent↗

[Severe cerebral lesions in pregnancy toxemia].

The authors report a case of pre-eclamptic toxemia, characterised by extensive cortical, sub-cortical and vertebro-basilar neurological lesions. The appearance of these lesions and their course were suggestive of the role played by toxemic vasculitis and vasospasm.

Adult↗

[Acute hepatic steatosis in pregnancy can be cured without interrupting the pregnancy].

Fatty liver during pregnancy is an acute hepatic disease of unknown origin. We report the case of a 24-year-old woman in whom the diagnosis was made on the basis of the histological examination. The disease did not disturb the normal course of the pregnancy and delivery. In the literature, it is generally suggested that pregnancy must be terminated in cases of acute fatty liver since no favourable outcome has been reported with continued pregnancy. We suggest that, in minor forms, close clinical observation and laboratory monitoring can provide the means of continuing the pregnancy to term.

Abortion, Therapeutic↗

[Prevention of nosocomial urinary tract infection: vesical catheter versus Penilex].

Nosocomial urinary tract infection is the most frequent nosocomial infection in many care units. Its main risk factor is the presence of a bladder catheter. Prevention is based upon the enforcement of hygiene recommendations which are not always carefully applied everywhere. We report a prospective study concerning 328 patients divided into two gropus. Group I patients (n = 161) had an indwelling bladder catheter. Group II patients (n = 167) had an external urinary drainage by Penilex. The incidence of nosocomial urinary infection was 2.4% in group II versus 26.7% in group I. Thus preventive efficacy of Penilex use appears to be well demonstrated.

Critical Care↗

[Guillain-Barre syndrome and pregnancy].

A case of polyradiculoneuritis, resembling Guillain-Barre syndrome, was reported during the sixth month of a first gestation. The patient was seventeen years old and also had toxaemia of pregnancy. The interaction between polyradiculoneuritis and pregnancy is slight and carries little risk of prematurity. Plasma exchange procedures can be used in pregnant women and the results of this treatment are similar to those in patients presenting with polyradiculoneuritis alone.

Adolescent↗

[Block of spermatic cord in surgery of the testis].

This study analyses 25 cases of spermatic cord blockade for scrotal surgery (hydrocele, spermatocele, tumor of epididymis). The spermatic cord was infiltrated, after identification of the pubic tubercle, with a mean total dose of 17 +/- 3 ml of a 2% lidocaine solution not containing adrenaline. The scrotal skin was infiltrated separately at the site of incision. Analgesia was excellent in 22 patients. The duration of analgesia was 82 +/- 33 min. No adverse effects occurred. It is concluded that the blockade of the spermatic cord is a convenient anaesthesia technique for testicular surgery.

Adult↗

[Preventive treatment of hemodynamic disorders during conventional spinal anesthesia].

The prevention of blood pressure fall during a conventional spinal anaesthesia effected with 20 mg (4 ml) of isobaric 0.5 p. 100 bupivacaine relies on the use of vascular filling and/or a vasoconstrictor. A randomized prospective study was performed to evaluate the comparative efficacy of these two treatments. 148 patients were included and divided into three groups. Group I (n = 50): 2.5 mg IV bolus of etilefrine followed by continuous infusion (0.35 mg.kg-1.h-1). Group II (n = 50): 30 ml.kg-1 infusion of saline isotonic solution for 90 min, with infusion rate according to blood pressure. Group III (n = 48) did not receive any preventive treatment. A blood pressure fall of more than 30% of the initial value was observed in 59 patients: 18% of the etilefrine group, 28% of the saline infusion group, 54% of the control group. This peculiar frequency of hypotension in the control group emphasizes the need of a preventive treatment. Haemodynamic changes were fewer and less important in the etilefrine group compared with the saline infusion group. No failure and a better tolerance in the vasoconstrictor group were also to be noticed. These clinical data suggest that etilefrine could meet satisfactorily the therapeutic requirements.

Anesthesia, Spinal↗

[Acute pancreatitis and pregnancy].

Acute pancreatitis during pregnancy is a serious condition and diagnosis is often difficult. The authors report the case of a 32-year-old woman in the 32nd week of her fifth pregnancy, in which the outcome was fatal for both mother and child. The cause of pancreatitis during pregnancy has been attributed to many factors, chiefly cholelithiasis. A number of recent studies have shown the relationship existing between the role played by pregnancy in predisposing to gallbladder disease with lithiasis. Many diagnosis errors are made in this condition. Thus modern treatment methods have improved the prognosis in acute pancreatitis but, when it occurs during pregnancy, diagnostic delays often lead to a gloomy outlook.

Acute Disease↗

[Postoperative rhabdomyolysis following surgery of a pheochromocytoma].

The authors reports one case of post operative rhabdomyolysis after surgery of pheochromocytomas. The diagnosis of rhabdomyolysis suspected on acute renal failure was confirmed on the increase of CPK and myoglobin blood levels. The findings on physical examination were normal. In this particular case, the operative position seems not implicated in the genesis of this rhabdomyolysis. Nevertheless, the long duration of surgery (4 h) is the major factor encountered in this pathology. Evolution was satisfactory after three haemodialysis sessions.

Adrenal Gland Neoplasms↗

[An unusual case of HELLP syndrome].

The Hellp's syndrome is a complication of gravidic hypertension which associates the microangiopathic hemolysis, the cytolytic hepatic anomalies and a thrombocytopenia. There are resemblences between the biologic and histologic forms of the thrombotic microangiopathy and Hellp's syndrome. In this publishing, we report one case of Hellp's syndrome which the particular character is that the hepatic and hemolytic biologic anomalies are still very discrete, where as the thrombopenia is deep; this led us to rediscuss about the authencity of Hellp's syndrome. A neurologic complication, particulary gravissim, is noticed in one case, it concerns the intracerebral hematoma with left deficiency syndrome.

Adult↗

[Cervical peridural anesthesia for carcinologic surgery of the larynx. 10 cases].

Cervical peridural anesthesia was associated to a general anesthesia with controlled ventilation in ten patients undergoing laryngectomy for cancer. All the patients (middle age 57 years) suffered chronic bronchopneumopathy. The cervical peridural approach is realized by puncture at the level C6-C7 with setting of a peridural catheter. After a test dose, a total volume of 18 ml of bupivacaïne at 0.33% is injected. Reinjections of nine ml of the anesthetic solution are realized after a mean delay 200 min. After induction with thiopental and pancuronium bromide, narcosis is maintained by N2O/O2, 0.5/0.5 associated to 0.5% halothane. The mean operating time was four hours and ten minutes. The anesthetic block obtained stretches from C2 to D4, after a mean delay 22 +/- 7 min. Analgesia is satisfying. Little changes occurs in hemodynamic state, except an almost constant bradycardia. Bleeding stay in range of laryngectomies. The awakening is immediate; the post-operative evolution is simple. No complication tied to the anesthesia has been observed.

Adult↗

[Severe hemobilia of cholecystic origin].

The authors report a case of severe hematobilia originating in the gall bladder itself ans associated with a cholecysto-colic fistula. They review the different etiologies of hematobilia and stress the major value of selective arteriography of the coeliac trunk and possible pitfalls in this condition. This case highlights the rare complications of cholelithiasis (hematobilia and cholecyto-colic fistula) and the severity of blood spoliation. Therapy is reviewed as a function of the lesion causing hematobilia.

Angiography↗

[Subcapsular hematoma of the liver, a complication of pregnancy toxemia].

The authors report three cases of subcapsular liver hematomas occurring after delivery and diagnosed by ultrasonography (1 case), and exploratory laparotomy (2 cases). These three cases compared with the data from the literature, illustrate the conditions of occurrence and the clinical signs of subcapsular liver hematomas during pregnancy or in the post-partum period. The frequency of this complication is most likely underestimated, since benign forms remain latent and the severe forms, responsible for sudden death, eludes the diagnosis in the absence of anatomical confirmation.

Adolescent↗

[Caustic lesions of the upper digestive tract].

A study of 108 patients who had ingested variable quantities of a caustic substance, most often for suicidal reasons. Hydrochloric acid was the substance most often encountered After stabilisation of any hemodynamic and respiratory disorders, all patients received emergency endoscopy. Subsequent therapy was based on the following endoscopic findings: --Patients, in whom the mucosa was normal, were not hospitalised. --The digestive tract of patients with stage I disorders was rested for 10 days. --Patients with stage III, disorders were operated on as an emergency especially when signs of gravity were present. --Patients with stage II disorders constituted the group which posed most problems in our study. These patients required enteral feeding as soon as possible, via a simple jejunostomy.

Adolescent↗

[Surgical treatment of primary hyperparathyroidism. Apropos of 11 cases].

Over a period of 10 years, 11 cases of primary hyperparathyroidism were operated on and identified as 7 adenomas and 4 hyperplasias. One post-operative death was noted in a 80 year woman with advanced disease. Three hypocalcemias and one temporary unilateral recurrent nerve plasy were observed. After the results of this series, various clinical forms were identified and surgical modalities were altered according to the intra operative findings.

Adenoma↗

[Compensation for bleeding in a surgical milieu. Importance of normovolemic hemodilution. Apropos of 25 cases].

In order to get round blood supply difficulties, 25 patients undergoing hemorrhagic interventions (blood loss average of 1,500 ml) were subjected to the techniques of normovolemic hemodilution. Preoperatively a volume of 1,080 ml of blood was taken in every patient (a total of 271 in all patients together); the blood was simultaneously replaced by 1,300 ml of macromolecules (modified fluid gelatin polymer and/or low molecular weight dextran according to disponibility). Two thirds of the taken amount are transfused to the patients preoperatively immediately after surgical hemostasis has been achieved or when the hematocrit is about 20%; the last third is administered in the immediate postoperative period. The economy of blood realised by this technique is considerable (119 units of homologous blood). The rationale depends on two essential particularities: on one hand, the diminution of blood loss since at a hematocrit of 25% the loss is only 50% of the globular mass which would have disappeared at normal hematocrit; on the other hand, the compensation of hemorrhage by transfusion of fresh autologous blood, eliminating homotransfusion reactions. The main hematocrit obtained 24 hours after transfusion is about 34%. Thus, economy of blood and rheological advantages (amelioration of microcirculation, increase of capacity of oxygen transport, increase of tissular oxygenation) must induce physicians to reexamine their behaviour in transfusion strategy and compensation of hemorrhage because the optimal hematocrit in normovolemy is of about 30%.

Adult↗