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Biomedical subjects

M Belogi

Publications and source records attributed to M Belogi.

12 recordsLinked to original sources
PubMed1987

Life quality in patients under hypotensive treatment.

The authors studied the life quality in a group of 74 patients--31 males and 43 females--affected with essential hypertension of World Health Organization I or II degree. All patients began treatment with frusemide at a dose of 25 mg once a day. The 35 non-responsive patients to frusemide were then treated, by random selection, with captopril at a dose of 25 mg twice a day, or nadolol at a dose of 80 mg once a day, for three months. The results show no significant differences on the hypotensive effect with either drug; in view of the incidence of side-effects of the two drugs, treatment with captopril is clearly better tolerated by the patients.

Antihypertensive Agents↗
PubMed1985

[Diuretics].

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Aldosterone↗
PubMed1985

Controlled trial on three beta-blockers: antihypertensive efficacy and effect on the hypertensive heart disease.

Treatment of 66 hypertensive patients with three different beta-blockers (atenolol 100 mg once a day; oxprenolol 80 mg twice a day; nadolol 80 mg once a day) for six months resulted in a significant reduction in blood pressure and heart rate, the maximum with nadolol, a significant amelioration in pre-ejection period/left ventricular ejection time ratio expressing the haemodynamic performance of the left ventricle with atenolol and nadolol, and a significant reduction left ventricular hypertrophy as expressed by the Romhilt-Estes index with all three drugs, but especially with nadolol.

Adrenergic beta-Antagonists↗
PubMed1983

Long-acting and short-acting diuretics in the treatment of hypertension.

A single-blind trial was carried out in 36 people with mild to moderate hypertension to compare the efficacy and tolerance of long-term treatment with furosemide and chlorthalidone. After a 30-day wash-out period, patients were treated for 6 months with a single daily dose of either 25 mg furosemide or 50 mg chlorthalidone. They were then crossed over to the alternative drug, after a 15-day wash-out period, for a further 6 months. Results from the 25 patients who completed the study period showed that both treatments were successful in reducing systolic and diastolic blood pressure significantly after 1 month and blood pressure was controlled at the lower level for the remainder of the study period. There was no statistically significant difference between the two treatments at the end of the trial in respect of their antihypertensive efficacy. However, patients on chlorthalidone showed a marked, significant decrease in serum potassium levels from 1 month onwards compared to patients treated with furosemide and at the end of 6 months 10 (25%) were considered to be hypokalaemic whereas only 2 (8%) of the furosemide-treated patients had serum potassium levels lower than 3.5 mmol/l. Few side-effects were reported and patient compliance was good in both treatment groups.

Adult↗