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Biomedical subjects

M Baykal

Publications and source records attributed to M Baykal.

At least 37 records · Page 2Linked to original sources
PubMed1982

[Amikacin - resistance in some bacteria isolated in Ankara, and its relation to R plasmids].

Four acinetobacter and 5 Ps. aeruginosa strains which were isolated in Clinical pathology Lab. of Hacettepe Univ. Med. School, and found to be resistant to Amikacin were tested for infectious drug resistance, using conventional in vitro transfer technique repeatedly. E. coli K12 Nalr (for Acinetobacters), and Ps. aeruginosa (for Pseudomonads) strains were used as recipients. For cultures and transfer experiments NB No : 2, and for the selection Mc Conkey Agar plates with nalidixic acid and proper antibiotics were used. Inspite of some variable and curious positive findings, it was not possible to transfer Amikacin - resistance to recipients with certainty. Results suggest that this characteristic was not controlled by R plasmids and hence was not "infectious", or at least could not been transferred by the technique we used.

Acinetobacter↗
PubMed1980

[Non-fermentative gram-negative bacilli: their distribution to clinical materials and antibiotic susceptibility (author's transl)].

A total of 7898 non-fermentative Gram-negative bacilli were isolated from various clinical materials. Pseudomonas (7526) was the most common among them. Alcaligenes faecalis (273), Acinetobacter sp. (93) and Flavobacterium (6) were the other non-fermentative Gram-negative bacilli. Most of them were found in urine and pus cultures, however they were also isolated from sputum, blood, and cerebrospinal fluid. Gentamicin was the most effective antibiotic in vitro. Fifty four per cent of Pseudomonas, 100% of Acinetobacter, and 70% of Alcaligenes faecalis were inhibited by tobramycin.

Acinetobacter↗
PubMed1979

[Clinical trial of parenteral trimethoprim-sulfamethoxazole].

The combination of trimethoprim-sulfamethoxazole has been used successfully in various infections. However the use of the combination was limited, due to the lack of a parenteral form of the drug. In this study a parenteral (i.m.) form of trimethoprim-sulfamethoxazole was given to 35 patients with various infections due to susceptible bacteria to the drug. Twenty-four patients had urinary tract infections, and 7 had various infections with gram negative organisms, and 4 had staphylococcal infections. In patients with urinary tract infection the cure rate was 62.5%. Twenty five per cent of the patients had persistent infection after treatment, and 12,5% had superinfection. The overall cure rate was 71,4% in 35 patients. No side effect was observed.

Administration, Oral↗
PubMed1977

[Comparison of various aspects of normal and filamentous forms of S. enteritidis].

For more detailed information on filamentous and normal forms of S. enteritidis, electronmicrographic studies and slide cultures were carried out. The filaments show similarity to normal forms of S. entertidis except for their length. They produce the normal forms of bacteria when transferred to suitable media. Some of the filaments exhibited various degrees of degeneration in their walls. Some of them consist of only a collapsed cell wall, because they lose their cell content. We think those are the filaments which are irreversible and not able to produce the normal forms of bacteria.

Bacteriological Techniques↗
PubMed1976

[Induced filament formation in S. enteritidis by means of different sodium and chloride salts and different carbohydrates].

We have previously observed filament formation in S. enteritidis which grew on media containing different salts and carbohydrates. In this study, sodium citrate, sod. carbonate, sod. molybdate, sod. acetate, sod. sulfate, potassium chloride, calcium chloride, saccharose and glucose were used as inducing agents. Different concentrations of most of the above substances were effective in filament formation in S. enteritidis. Temperature (37 degrees C and room temperature), pH of media and state of media (liquid and solid) are also found to be effective in filament formation in some levels.

Carbohydrates↗
PubMed1976

[Comparison of various aspects of normal and filament forms of S. enteritidis IV].

Induced filament formation of S. enteritidis by means of sodium chloride was previously reported. In this study various aspects of normal and filament forms of S. enteritidis are compared. Filament forms had lost some of their biochemical activities when compared with the normal forms of S. enteritidis. There was no serological difference between the two forms. We were unable to show any difference in antibiotic sensitivity, because concentrated sodium chloride inhibited cell growth. No difference was observed between the two forms in pathogenity against mice. The resistance to heat was decreased in filament forms. In addition to these, staining and spreading of nuclear elements showed some variations in the young and old filaments.

Animals↗
PubMed1976

[An abscess formed by Salmonellae in a postoperative tumor cavity].

A focal salmonella infection was detected in the postoperative cavity of a astrocytoma. S. paratyphi B was isolated several times from the same cavity during a 12 months period. Although effective antibiotics were administered in addition to the surgical cleaning procedures S. paratyphi B could not be eradicated.

Abscess↗
PubMed1976

[Induced filament formation in various types of Salmonella and other bacteria by means of sodium chloride].

Induced filament formation in various Salmonellae (S. typhimurium, S. newport and S. cholerae suis) and other bacteria Proteus, E. coli, Ps. aeruginosa and Sh. flexneri was seen. Sodium chloride was used as inducing agent in filament formation. The filaments were reversible morphologic variants and transformed to normal bacteria when the effects of inducing agent were removed from the growth media.

Bacteria↗