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Biomedical subjects

M Bartel

Publications and source records attributed to M Bartel.

At least 55 records · Page 3Linked to original sources
PubMed1982

[Animal experimental model of lung contusion].

Introduction and discussion of an experimental animal model to the representation of an isolated lung contusion in rats. The damage is realized by means of pressure waves. There can be observed distinct lung contusions - even unilateral - without chest wall lesions or extrathoracal injuries. One can also recognize temporal lapses of different intensity of the trauma. The model appears suitable to the presentation of a possible independent pathogenesis of the lung contusion.

Animals↗
PubMed1981

[Experimental animal studies on lung contusion].

Isolating lung contusions were represented by means of animal experiments in rats. The mechanism of the trauma was a bounce against the thorax wall with a steel cylinder. Macroscopic pulmonary alterations, lung weights, the frequency of secondary injuries as well as the mortality rate are the parameters of the lesion. The lung alterations shows communities with human lung contusions. The model is suitable for the specification of histological and morphological alterations and for the pathogenesis of lung contusions as well as for the quest of diagnostic parameters. The intensity of the lung contusion is limited by initial rupture of vessels. To the test of clinical therapy and for the release of limited lung contusions there are required models with other mechanisms of trauma.

Animals↗
PubMed1980

[Arterial embolectomy in acute peripheral vascular occlusion (author's transl)].

A series of 68 arterial embolectomies in 59 patients performed during 1970 to 1979 is presented. Limb salvage rate was 67,5%, amputation frequency after embolectomy 5,9%, the mortality rate came up to 17,6%. An analysis of some factors affecting the results after embolectomy, such as causative heart disease, anticoagulation treatment, and time interval between lodgment and removal of embolus, is given. Good results can be expected if surgical treatment is consequently combined with pre- and postoperative anticoagulation and therapy of causative heart disease.

Adult↗
PubMed1979

[Time-dependent changes in the lactic acid level of ischemic muscle tissue under conditions of arterial embolism, simulated in animal experiments].

It may be summarized that under the condition of embolism in animal experiments the lactate level is significantly changed depending on the duration of ischemia. Thus, for judgement of a hypoxic damage of muscle tissue this parameter appears to be useful. A more precise analysis would be imaginable, when the degree of tissue damage could be stated according to a certain lactate level. For this, however, the reported results must be compared with a randomized series of human patients suffering from arterial embolism, since the present studies concern the muscles of rats.

Animals↗
PubMed1978

[Results later many years after TEA in femoro-popliteal segment (author's transl)].

Our results later many years after 231 TEA in femoro-popliteal segment are based to examinate the indications of this reconstructive operation and to compare with other methods of arterial reconstruction. Resulted: the TEA is always a good method of biological worth without risk. This method authorized to indicate the reconstruction of chronical arterial occlusions. However the method is not to apply to all arterial occlusions without criticism only to selected patients.

Age Factors↗
PubMed1977

[Late sequelae of rib fractures].

For an assessment of the late lesions after rib fractures 108 patients having had an accident between 1968 and 1973 were followed up. As to the individual signs observed, the patients were very heterogeneous. Radiodiagnostic, spirometric and scintigraphic data were compiled in order to characterize the late morphologic and functional lesions. By means of correlation and discrimination analyses as well as tests of significance we found that the extension of the late lesions depends either on the age of the patient nor on the number of fractured ribs but, instead, on concomitant intrathoracic lesions. The late morphologic lesions such as deformedly healed rib fractures and pleural thickening were the substrate for the ventilative and circulatory disturbances of the lung.

Adult↗
PubMed1977

[Vascular reconstructive procedures in patients with chronic occlusive arterial diseases and diabetes mellitus (author's transl)].

97 diabetic patients of 734 patients with a chronic occlusive arterial disease were observed in the years from 1968 to 1974. It was established the operability of arterial occlusions are influenced by heaviness, duration and setting in the diabetes mellitus only a little. The indication to operate is determined by the three-points-regulation at the diabetic patients, too. Vascular reconstructive procedures were only possible at each of a second or third patient independent of diabetes mellitus. 28 vascular reconstructive procedures in the femoro-popliteal reach were made at 22 diabetic patients. The results were successful in more about than 80 per cent by explorations from 1 to 5 years after operations.

Adult↗
PubMed1977

[Haemodynamic and respiratory changes after lung resection (author's transl)].

After lobectomy a slight increase of pulmonary arterial pressure can already be observed in the state of rest. The resistance of the pulmonary vessels reveals a marked dependance on the date of operation, it increases moderately on strain, but more significantly in the state of rest. At the same time cardiac output is decreased due to the exhaustion of the myocard after straining. Cardiac insufficiency developing postoperatively is due to the reduction of pulmonary hypertension. The reduction of VC and a slight increase of resistance do not cause the arterial PO2 pressure to be lowered under conditions of strain or rest.

Blood Pressure↗
PubMed1976

[Prognostic value of histological rare breast cancer (author's transl)].

Among 835 cases of female breast cancer in the years 1951-1971 we found 44 histological rare cancer (comedo-carcinoma 21, carcinoma cribosum 1, gelatinous carcinoma 8, squamous cell carcinoma 3, mixed carcinoma 11). In agreement with the literature we are able to underline the favourable prognosis of the slow growing forms of the neoplasms like gelatinous carcinoma, comedo-carcinoma and carcinoma cribrosum opposite to squamous cell carcinoma and mixed carcinoma.

Adenocarcinoma↗
PubMed1976

[Pulmonary changes in a female patient with Pringle's syndrome (author's transl)].

The Pringle's Syndrome (Synon. adenoma sebaceum) is a very variable illness, based on a congenital neuroectodermal genetic defect. The hereditary transmission is dominant and it can be very various. The pulmonary involvement in Pringle's Syndrome is very rare. A case of a 25 year old female patient is demonstrated. She suffered on spontaneous pneumothoraces in both sides and had many typical alterations in other organs. Further examinations revealed disseminated small cystic alterations in the lung. Histologically these changes are based on a congenital defect of bronchioli. The patient's cardiopulmonal efficiency is assessed regarding to its prognosis. Finally the necessity of genetic care for patients with Pringle's Syndrome is pointed out.

Adult↗
PubMed1976

[Mediastinoscopy and scar-keloid's in boeck's sarcoid (author's transl)].

The paper represents the results of the mediastinoscopy in 135 cases of Boeck's sarcoid. The frequent formation of keloid's in the scar of the mediastinotomy is emphasized. The histological examinations of the scar keloid's after mediastinoscopy are compared with histological examinations of scars after resections of the thyroid glands. The possible reasons of the differences are discussed.

Adult↗
PubMed1976

[Mediastinoscopy in preoperative assessment of operability in patients with bronchial neoplasms (author's transl)].

The results and conclusions of the endoscopic exploration of mediastinum in 352 patients suffering from bronchogenic cancer are analysed. The importance of mediastinoscopy is emphasized especially in the assessment of operability. In the opinion of the authors the cancer is not operable, if metastases are found in the paratracheal and contralateral lymphnodes. Only in young men the extended resection should be done in individual cases if mediastinal lymphnode metastases are detected. Regarding these indications the rate of explorative thoracotomy could be reduced to 10%. The particular importance of preoperative examination of load capacity of the heart and circulatory system is stressed. Finally it is concluded, that an decisive improvement of the common prognosis of the bronchogenic cancer is only possible by an earlier detection and a more rapid introduction of therapy, but not by the extension of the surgical procedures. The enlargement of the surgical procedure should be decided individually. The great possibilities hencefollowing for the mass x-ray examinations are emphasized.

Adult↗
PubMed1976

[Complications of mediastinoscopy and their effects on the choice of indication (author's transl)].

Complications of 735 mediastinoscopies are evaluated. In the small number of early complications the bleedings and unjuries of pleura dominate in the described group of patients. At no time a thoracotomy was necessary. The danger of bleeding from an aneurysma of the aorta is pointed out, which is rare but possible early complication. The inoculated metastases do not deteriorate the prognosis of the bronchogenic cancer, if the mediastinoscopy is strictly limited to the paratracheal and tracheobronchial lymphnodes. The observation of a metastasis in the collar cicatrix following three months after mediastinoscopy due to cancer of the oesophagus is described. The low number of observed complications in the opinion of the writers does not justify to limit the range of indications for mediastinoscopy, its diagnostic value is high.

Adult↗