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Biomedical subjects

M Bartal

Publications and source records attributed to M Bartal.

31 records · Page 2Linked to original sources
PubMed1991

[Non-Hodgkin's lymphoma disclosed by an intrabronchial tumor. Apropos of a case].

Non Hodgkin's lymphoma (LNH) presenting as a localised tumour is exceptional and nearly always appears during the course of disseminated disease. We report a case where the primary disease was an endobronchial tumour and the entire clinical picture related to pulmonary symptoms. A 70 year old lady was found to have a left sided pulmonary opacity following a cough with minimal expectoration and accompanied by chest pains and dyspnoea. The chest abnormality progressed for 3 years 9 months before an endobronchial tumour was discovered at bronchoscopy in the left upper lobe and from which a biopsy revealed an LNH with small cells of low degree of malignancy. In addition there was splenomegaly and an infiltration of bone marrow by the lymphomatous process which was evidence of a disseminated form of LNH. To our knowledge our observation is an extremely rare case where an endobronchial tumour revealed a non Hodgkins lymphoma.

Aged↗
PubMed1989

[T lymphocytes in the circulating blood and pleural fluid of patients with tuberculosis or cancer].

Inflammatory pleurisies in the adult are particularly rich in CD4 lymphocytes, capable of inducing and facilitating the immune reaction. The aim of this study was to determine the percentage of CD4 and CD8 lymphocytes in pleural fluid and blood in 13 patients with tuberculous pleurisy and 12 patients with pleural neoplasms, to establish the diagnostic value of this analysis. Independent of the etiology of the effusion there is a concentration of CD4 T lymphocytes in the pleural fluid compared to the blood (49.52 +/- 12.36% and 39.28 +/- 6.74%, respectively, p value less than 0.001). However, there was a similar concentration for the two types of disorders studied with 59.92 +/- 7.26% for tuberculous pleurisies and 45.83 +/- 6.26% for neoplastic effusions, thus this technique does not make the diagnostic orientation any clearer.

Adult↗
PubMed1988

[Smoking in Morocco: an outline of the anti-smoking campaign].

In Morocco, as in many developing countries, tobacco use has become a plague which aggravates the many already existing problems. A coordinated prevention programme which included research and a variety of educational efforts, has been underway for the past five years. The preliminary stage of the non-smoking campaign consisted of research through use of a variety of standardized questionnaires. The research results showed tobacco use in Morocco to be the following: 23.8% of secondary students are smokers with variation according to family, culture, environment and sex (33% male vs. 8.6% female); 33.8% of university students smoke, including those in Medical Schools; 52.1% of adults in the work environment smoke, including doctors. The rate declines drastically among practicing muslims (between the ages of 14 and 65) to 9.8%. The use of other drugs is significantly higher in students who use tobacco (25%) than those who do not (1.5%). A common factor appeared regardless of age, sex, or occupation: there was insufficient information available concerning the harmful effects of smoking. An educational campaign was therefore launched. As the youth were considered to be the most vulnerable target group, a major part of the educational efforts was concentrated on them. A variety of activities was implemented including conference-debates using audiovisual supports; radio and T.V. broadcasts; contests run with the assistance of the CIPADED (International Committee for the Prevention of Alcohol/Drug Dependence). Information of the harmful effects of tobacco use was diffused in workplaces, government offices, and at public assemblies. Efforts were also implemented to promote adoption of legislation which would limit tobacco consumption.(ABSTRACT TRUNCATED AT 250 WORDS)

Adolescent↗
PubMed1982

[Acetylation phenotype of isoniazid in Morocco. Preliminary study of 100 cases].

A preliminary study to determine the acetylator phenotype for Isoniazid was carried out for the first time on 100 patients. A correlation was shown between the blood and urinary methods; 59% were rapid acetylators and 41% slow acetylators, which were similar levels to those found in Black Africa. The predominance of rapid acetylators certainly explains the excellent tolerance of the high dose of INH (10 mg/kg) used in Morocco. If the determination of the acetylator phenotype could not be used systematically in our country, in view of the individual adaptation to the dosage--the dosage might, on the other hand be worked out in a prompt way before toxic signs appear at a dose of 10 mg/kg or under, of INH--thanks to the calculation of the index of inactivation estimated from a single sample.

Acetylation↗