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Biomedical subjects

M Barbuscia

Publications and source records attributed to M Barbuscia.

65 records · Page 4Linked to original sources

[Ileum-colon junction benign obstructions].

The Authors discuss on anatomical and functional characteristics of ileum-colon junction, physiological narrowing in alimentary tract and often involved in benign obstruction. They report their series and analyze all inflammatory or not inflammatory diseases potentially involved, by describing them shortly and giving some information about their clinical features and imaging. The treatment of this obstruction will be done as soon as possible, before wall lesions force to make a larger resection.

Adult↗

[Acute pancreatitis: our experience in the light of natural history].

The Authors enumerate main steps of acute pancreatitis natural history. Then they discuss their last five years case-report. After having stated that clinical presentation depends on anatomo-pathological conditions, they consider aetiological causes and morphopathogenetic moments involved in the onset and development of this disease. They conclude stating how only proper diagnosis and treatment can prevent its potential evolution in multiorgan failure.

Acute Disease↗

[Etiopathogenic hypothesis on carcinoma of the gallbladder: our study].

The authors are interested in determining causes of gallbladder cancer (GBC). By this intention, they theorize a correlation between genetic modifications (which are responsible of malignant transformation of biliary epithelium) and some intestinal infections. From 1999 to 2004 they observed 15 GBC and all 15 gallbladder have been analyzed histologically and from microbiological aspect; by these means from 1999 till 2004 they have studied also 30 persons with colelithiasis. The authors noticed that bile of both groups contained, in three cases in the first and in 8 cases in the second, a germ named Escherichia Coli which normally lives in intestine, while in 10 operated gallbladders of the first group and 12 of the second there was a positive for k-ras. They are studying to confirm their theories.

Aged↗

[Stomach GIST].

Gastric stromal tumors give diagnostic and therapeutic problems, especially with regard to histopathologic identification and biological behavior. These tumors are very rare in all case reports. These ones are the most frequent of all alimentary tract. They are often incidentally found; because of their potential transformation, they have to be treated by respecting oncologic eradication standards and observing prognostic criteria based on a correct histopathologic evaluation (neoplasm localization and dimension, its structure, presence of cytological atypisms, mitotic index, ploidia, surgical resection). Then there has to be a good follow-up program.

Adult↗

[The onset of local recurrences after radical therapy for rectosigmoid carcinoma].

The authors after considering the natural history in 116 patients with rectosigmoid carcinoma examine a number of parameters and their significance in terms of predicting recurrence. Following curative surgery the authors conclude a particular significance is satisfying quality of life in patients with rectosigmoid carcinoma.

Adult↗

[Colorectal carcinoma in young patients: review of 10-year experience].

The authors, in reaffirming the high incidence of the mucin-producing type of colo-rectal adenocarcinoma in young patients, underline the considerable aggressiveness of this tumor. After a brief note on the etiopathogenetic hypothesis which could explain such behavior, the factors usually contributing to a worsening of the prognosis are reviewed. Thus, the Authors report their series and conclude affirming as indispensable to arrive to an early diagnosis.

Adenocarcinoma, Mucinous↗

[Wilms' tumor in adults].

The Authors report a case of Wilms' tumor in a 38-year-old woman. Through a review of such neoplastic condition some etiopathogenetic and clinical considerations are made. It is concluded that postsurgical adjuvant therapy in adulthood must not differ from that of childhood.

Adult↗

[Malignant melanoma of the skin: current diagnostic and therapeutic approaches].

The Authors claim that the treatment of malignant melanosis of the skin is a problem of undiminished topical interest owing to its highly aggressive characteristics. Risk factors and pre-neoplastic lesions are reviewed, and the signs of malignant transformation are described along with the appropriate treatment. The Authors stress the importance, for therapeutic and prognostic purposes, of accurate clinical staging and macro- and microscopic study of the primary tumour. They also describe their own therapeutic approach, which involves the use of a CO2 laser for resecting the primary tumour. They present their patient population and conclude by observing that the progress achieved over the past decade is due both to earlier diagnosis and to improvements in the various therapeutic means available.

Adult↗

[Spontaneous retroperitoneal hematoma from ileopsoas muscle bleeding. A case report].

The Authors report a case of spontaneous retroperitoneal hematoma due to iliopsoas muscle bleeding. The different causes responsible of such hematomas are taken into account as well as clinical, therapeutical and pathophysiologic aspects connected with the spontaneous bleeding of the iliopsoas muscle. As in the case observed, the Authors suggest that often a careful wait-and-see approach represents the most appropriate therapeutical choice.

Aged↗

[A peculiar anomaly of the main biliary duct: choledochal cystic dilatation].

The Authors report a case of choledochal cystic dilatation and examine this particular anomaly of the main biliary duct analysing the complex classification. After a brief review of the embryology of the hepato-pancreatic ring, etiopathogenetic theories, clinic characteristics, as well as diagnostic and therapeutic possibilities for this affection are taken into account. It is concluded that the best therapeutic choice should be always based on an accurate evaluation of the anatomo-pathological conditions in each single case.

Adult↗