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Biomedical subjects

M Barbato

Publications and source records attributed to M Barbato.

67 records · Page 4Linked to original sources

Pregnancy complications in natural family planning users.

A multicenter cohort study was designed to assess pregnancy outcome among natural family planning (NFP) users, and provide the opportunity to address complications in NFP users by planning status and by timing of conception with respect to day of ovulation. There were 877 singleton births in this sample. Complications evaluated were abnormal vaginal bleeding, urinary tract infection, vaginal infection, hypertension of pregnancy, proteinuria, glycosuria, and anemia. There was no significant difference in the mean age, number of prenatal visits or birth weight among optimally and non-optimally timed pregnancies or for planned and unplanned pregnancies. There were higher incidences of "parity 2 or more" and current smokers in the non-optimally timed pregnancies and lower incidences of prior pregnancy loss and "currently employed" in the non-optimally timed pregnancies. There was little difference in pregnancy complications with respect to pregnancy timing, with the exception of a significant increased risk of vaginal bleeding late in pregnancy among non-optimally timed conceptions (11.5%) compared to optimally timed pregnancies (5.2%, RR = 2.2, 95% CI 1.3-3.7). More differences were observed in pregnancy complication rates by planning status. Unplanned pregnancies were associated with significantly more late pregnancy bleeding, vaginal infections, proteinuria, glycosuria and medication use than planned pregnancies. Unplanned pregnancies had lower incidences of maternal anemia. Complications of pregnancy were low in this NFP population, irrespective of planned versus unplanned status. Women with planned pregnancies had even fewer complications during pregnancy than women with unplanned conceptions, suggesting that women using NFP to plan their reproduction may be at particularly low risk.

Cohort Studies↗

[Paucity of interlobular bile ducts in twins and maternal abuse of psychopharmaceuticals during pregnancy].

We report the case of twins with intrahepatic cholestasis in "paucity of interlobular bile ducts". Both the children presented an associated cardiac defect even if dissimilar and a transient tubulopathy. Despite the presence of these alterations we suppose that these cases can be included among the group of rare nonsyndromic paucity of interlobular bile ducts. The different extent of the pathology in the two patients suggest a toxic etiology which could have struck more severely the twin who were less protected by the utero-placental barrier. In the literature reports we found some cases of extrahepatic biliary atresia related with maternal amphetamine addiction, but no cases of intrahepatic atresia. As during pregnancy the mother had abused of a number of drugs and in particular of amphetamine, we suppose that the amphetamine addiction can account for the hepatic pathology.

Abnormalities, Drug-Induced↗

[Correlation between indicators of the fertile period of the menstrual cycle and ultrasonically-determined ovulation].

The authors intend to verify the reliability of some indices set up for the assessment of the fertile period of the menstrual cycle in women. The patterns of the following indices were studied and related to the day of ovulation, as detected by pelvic ultrasonography, in 42 cycles in healty women: the urinary surge of luteinising hormone tested by radioimmunoassay (R.I.A.), urinary surges of estrone-3-glucuronide (E1-3-G) and pregnanediol-3 alpha-glucuronide (Pd-3-alpha-G) tested by chemiluminescence immunoassay, cervical mucus at the vulva and basal body temperature (B.B.T.) recorded by self-observation. The patterns of these parameters have shown a various temporal relationship and reliability for detection of the fertile days of the menstrual cycle.

Adolescent↗

[Study of the SNC using MRI in a case of Lowe's syndrome].

A case of Lowe syndrome is reported. This syndrome is characterized by ocular, cerebral and renal defects. MRI investigation showed severe thickness of the corpus callosum and defective cerebral development.

Brain Diseases↗

[Type-III acrocephalosyndactylia (Saethre-Chotzen syndrome). Description of 2 cases].

The acrocephalosyndactylia III is a syndrome, which follows an autosomal dominant mode of inheritance, characterized by premature fusion of the cranial sutures in association with mild cutaneous syndactyly. The authors describe two cases recently come to their observation and point out the usefulness of the imaging diagnostics (CT, MRI) in finding anomalies specific of this affection.

Acrocephalosyndactylia↗

[Osteomyelitis and arthritis caused by Streptococcus group B in a 40-day-old boy].

Group B streptococci (GBS) have gained much attention in recent years as a cause of serious infection in the newborn. Traditionally two clinical syndromes have been defined as "early onset", with fulminant septicemia, pneumonia and meningitis, and "late onset", with a mild meningitis. More recently some previously unrecognized clinical presentations of GBS disease have been documented. These include asymptomatic bacteremia, septic arthritis, osteomyelitis, ethmoiditis with orbital cellulitis, pneumoniae with empyema, conjunctivitis. The literature to date reports 30 instances of osteomyelitis due to GBS. This report describes a forty days infant with a group B streptococcal osteomyelitis of the proximal humerus. Has been also emphasized the increased frequency and the benign clinical course of streptococcal osteomyelitis in the neonate.

Arthritis, Infectious↗

[Lyme disease in central Italy. Description of a case of a 3-year-old girl].

The Authors describe a case of Lyme disease in a 3 year old child who lives in the center of Italy, in the Rome area. In this report it has been underlined the presence of Lyme disease also in central Italy and the importance of early diagnosis and therapy in order to prevent severe complications.

Child, Preschool↗