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Biomedical subjects

M B Wilson

Publications and source records attributed to M B Wilson.

28 records · Page 2Linked to original sources
PubMed1982

Increased recovery of Aspergillus flavus from respiratory specimens during hospital construction.

An increase in the recovery of Aspergillus flavus from respiratory specimens occurred among hospitalized patients during a several-month period in 1977. Notably, 86% of the patients with positive culture results were located in an older hospital section adjacent to a building construction site that created great amounts of dust in the hospital's vicinity. Airborne contamination was suspected and results of air sampling showed A. flavus in 80% of old wing patient rooms (average, 8 A. flavus/positive room) compared with only 23% of the contiguous newer wing patient rooms (average, 1 A. flavus/positive room). Inspection of the main mechanical ventilation units in the two hospital sections disclosed numerous defects in the unit in the old wing and a properly functioning unit in the new wing. After repairing the defective unit, a significant reduction in the recovery of A. flavus from clinical and environmental specimens was noted.

Adult↗
PubMed1978

Deception among smokers.

Subjects in two different clinical trials who had been advised to stop smoking were asked if they had done so. Some 22% of subjects (11 out of 51) in the first trial and 40% (33/82) in the second trial who said they had stopped smoking were found to have raised carboxyhaemoglobin concentrations. Deception appears to be common in people trying to stop smoking.

Adolescent↗
PubMed1976

The covalent coupling of proteins to periodate-oxidized sephadex: a new approach to immunoadsorbent preparation.

Proteins were covalently coupled in good yield to periodate-oxidized Sephadex. The reaction was studied in detail with respect to Sephadex type, sodium m-periodate concentration, protein (albumin or immunoglobulin) concentration, time course, temperature dependence, and pH optimum. The complexes were stable and were used successfully for the immunoadsorption of sheep anti-rabbit immunoglobulin antibodies.

Animals↗
PubMed1973

Control of phosphoenolpyruvate synthesis in guinea-pig mitochondria.

1. The synthesis of phosphoenolpyruvate and the O(2) consumption from the tricarboxylic acid-cycle intermediates citrate, alpha-oxoglutarate, malate and succinate by guinea-pig mitochondria were compared. Malate was the most effective of these precursors; there was no synthesis of phosphoenolpyruvate from succinate. 2. The addition of palmitate, acetoacetate and ATP enhanced the synthesis of phosphoenolpyruvate from citrate and alpha-oxoglutarate. Palmitate and ATP increased the O(2) consumption, whereas acetoacetate had no effect on this parameter. 3. Octanoate depressed the synthesis of phosphoenolpyruvate from citrate, alpha-oxoglutarate and malate and increased the O(2) consumption. Pentenoic acid had no effect on phosphoenolpyruvate synthesis from any of the substrates used, although it increased the uptake of O(2). These findings might be relevant to the control of gluconeogenesis in vivo.

Acetoacetates↗