Biomedical subjects
Publications and source records attributed to M B Shtark.
Prerequisites for developing brain activity topographic mapping and its present status are given. Its advantages and disadvantages, use potentialities in the diagnostic practice of neurological and mental hospitals are discussed.
Water-soluble proteins in the CNS of Helix pomatia were studied by the method of disk electrophoresis in polyacrylamide gel. The protein Rf 0.58 proved to be absent in young snails, while in adults its amount varied from 3% (naive snails) to 6-10% (trained animals) of the proteins separated by the method used. Incubation of the adults' ganglia in saline containing serotonin or NaF led to a significant elevation of the protein Rf 0.58 quantity. Neither serotonin nor NaF induced the protein Rf 0.58 in the young snails. We suggest the protein Rf 0.58 to be related to G-proteins. Late maturation of G-proteins might be one of the reasons of low behavioural plasticity in the young snails. Influence of acetylcholine on the protein synthesis in the identified "pool D" neurons was studied too. Protein fractions were identified, in which the intensity of labelling increased up to 400-500% of the control level. Acetylcholine is supposed to modulate the protein synthetizing system in these neurons.
The paper describes a system able to combine conventional techniques of diagnostic x-ray imaging with direct digital imaging on the original receiver with a resolution of 1.2 lin/mm. Digital roentgenography may be introduced into medical practice basing on the system of computers at the working places of roentgenologist and his assistant. Data base of long-term storage of x-ray images and input software for each x-ray picture are outlined. The authors have some experience of utilizing the system in the random sequence of patients (20,000) in general and specialized hospitals of Novosibirsk.
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