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Biomedical subjects

M B Rose

Publications and source records attributed to M B Rose.

7 recordsLinked to original sources

The value of the pre-clinic intravenous urogram in the earlier diagnosis of the cause of haematuria.

The early treatment of patients with bladder cancer reduces mortality. By arranging a pre-clinic intravenous urogram we reduced the time from receipt of the General Practitioner's referral letter to making a diagnosis from 85 to 67 days and saved on clinic time and resources. A further reduction to 52 days was made by not using any out-patient time at all. Significant saving of time and resources is possible without any disadvantage to the patient.

Ambulatory Care

A computer program for urology.

Modern information technology offers new opportunities for the storage and manipulation of clinical data within hospital departments. We have designed and put into use a microcomputer system for urology. Its basic structure and main functions are described.

Carcinoma, Transitional Cell

Partial nephrectomy for stone disease.

The results of 227 partial nephrectomies for stone were reviewed. Radiologically visible calcification remaining in the kidney at the end of the operation increased the risk of further stone formation. Ipsilateral and contralateral true recurrence rates after partial nephrectomy were the same, and increased with time up to 34% at 20 years. Ipsilateral recurrence rates after partial nephrectomy were half those found in a similar study of nephrolithotomy, pyelolithotomy and ureterolithotomy. Anatomical factors are important in stone formation, and partial nephrectomy is of value in the management of renal stones.

Female

Renal stone formation. The inhibitory effect of urine on calcium oxalate precipitation.

The mechanism of renal stone formation is not fully understood. This report describes an investigation into the effect of urine on the precipitation of calcium oxalate from dilute solution. Over 33 min a 5 per cent solution of urine caused considerable inhibition of precipitation. The degree of this inhibition was related to the concentration of the original urine. An "artificial urine" composed of 12 solutes present in normal urine had some inhibitory effect, but less than that of equiosmolar true urines. Inhibition was also related to the percentage of urine present. This inhibitory effect may be important in the prevention of renal stone formation in normal people by delaying crystallization until urine reaches the lower urinary tract.

Adolescent