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Biomedical subjects

M B Lewis

Publications and source records attributed to M B Lewis.

At least 55 records · Page 3Linked to original sources
PubMed1980

Management of infants with Robin anomaly.

Congenital micrognathia and secondary glossoptosis, with or without cleft palate, constitute the Robin anomaly. Neonates with this condition are usually at great risk for life-threatening respiratory and feeding problems. The approach to the management of infants with this condition has included, in order of increasing complexity, positioning of the patient, surgical tongue-lip adhesion and tracheostomy. Because of dissatisfaction with the effectiveness of surgical tongue-lip adhesion, and a desire to avoid performing a tracheostomy, a trial of intense non-surgical management was instituted. Ten consecutive patients admitted to the Boston Floating Hospital with Robin anomaly were treated successfully by positioning, without requiring tongue-lip adhesion or tracheostomy. Medical management procedures are outlined and discussed.

Boston↗
PubMed1980

Hypotelorism, nasomaxillary-hypoplasia and cleft lip and palate in a patient with normocephaly and normal intelligence--a case report.

A patient with hypotelorism, nasomaxillary hypoplasia and cleft lip and palate is presented. The absence of an associated intracranial abnormality, mental retardation or seizures places this patient in a separate category from those described by deMyer. Her intelligence is above normal but at four years of age, she is having psychological problems and difficulties interacting with her peers.

Child, Preschool↗
PubMed1980

A family with the popliteal pterygium syndrome.

A family with the Popliteal Pterygium Syndrome is presented. The father was born with a cleft of the palate and lower lip pits. Two of the three offspring showed extensive involvement of the palate, gums, and lips with minimal involvement of the lower limbs, genitalia, and nails.

Abnormalities, Multiple↗
PubMed1980

The effects of pharyngeal flap surgery on laternal pharyngeal wall motion: a videoradiographic evaluation.

Twenty patients undergoing pharyngeal flap surgery to correct velopharyngeal incompetence were studied by speech videofluoroscopy pre- and postoperatively to determine the effects of the surgical procedure on lateral pharyngeal wall motion. Within the limits of clinical judgment and for purposes of surgical planning, the motion was not altered. The implications of this are discussed.

Cineradiography↗
PubMed1978

Developmental abnormalities associated with long arm deletion of chromosome No. 6.

A patient is reported who had a partial terminal deletion of the long arm of chromosome No. 6. His clinical findings included development delay, failure to thrive, neurologic abnormalities, and multiple congenital malformations. Among the malformation were unusual facial features, cleft palate, atrial septal defect, and abnormalities of the external genitalia. The patient's features are compared with others who may have material deleted from the long arm of chromosome No. 6.

Abnormalities, Multiple↗
PubMed1976

Inhibition by theophylline of phagocytosis in Acanthamoeba castellanii.

Theophylline inhibited the phagocytosis of latex beads by Acanthamoeba castellanii (Neff). The cells recovered the ability to engulf beads after 1-2 hr of exposure to theophylline. Cells which have been exposed to 25 mM theophylline for a period of inhibition and recovery were not inhibited further by incubation with a fresh medium containing the same concentration of theophylline. However, the medium in which the cells recovered was as effective as a fresh medium in inhibiting phagocytosis in a fresh batch of cells, suggesting that the development of insensitivity to theophylline inhibition resides with the cells themselves. Dibutyryl cyclic AMP also inhibited bead uptake.

Amoeba↗