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Biomedical subjects

M B Lee

Publications and source records attributed to M B Lee.

84 records · Page 5Linked to original sources
PubMed1967

Urinary amino acid excretion in subjects with leukaemia.

Urinary amino acid chromatograms were studied from 33 patients with various types of leukaemia and 71 control subjects. Marked variations were found in the excretion of methionine, threonine, valine, leucine, tyrosine, histidine, and aspartic acid.

Amino Acids↗
PubMedDate not supplied

MacCueSee: a quality control program for the Macintosh computer.

MacCueSee was written to perform routine calculations on quality control concentration values from radioimmunoassay. It is written in Microsoft QuickBASIC for the Apple Macintosh computer. The program calculates within and between assay standard deviation (S.D.) and coefficient of variation from a spreadsheet file containing concentration values of controls analyzed. It also calculates the average concentration +/- 1 S.D. and contraction +/- 2 S.D. to establish between assay ranges. Its flexibility permits varying replicates between assays and automatic exclusion of missed assays. Within assay variability calculations are made for single, duplicate, and triplicate tubes. Results are displayed and can optionally be printed. In addition to radioimmunoassay, MacCueSee can be applied to a number of analytical methods in which quality control is monitored. An example of program use is included.

Microcomputers↗
PubMedDate not supplied

Rural women and power in Pakistan.

Perceptions of power in women living in rural villages in Pakistan were explored. The Lee-Hezekiah Power Perception Scale was developed by the authors to measure women's perception of their power. The instrument was administered in interviews conducted by a group of Lady Health Visitors who were participating in a project funded by the Canadian International Development Agency. Sixty-nine women ranging in age from 20 to 65 were interviewed. One-way analysis of variance revealed that the oldest group perceived themselves to have more power than the youngest group perceived themselves to have. Stepwise multiple regression indicated that the number of male children a woman had was predictive of the amount of power she perceived herself to have. The results are discussed in relation to existing literature on women and power in developing countries. Implications for further research on women's perceptions of power and health are discussed.

Adult↗
PubMedDate not supplied

A retrospective study of treatment outcome for patients with non-insulin-dependent diabetes at an inner-city hospital.

The medical records of 173 consecutive patients with diabetes who were newly enrolled in our facility in 1990 were analyzed for blood glucose at 1 year. A total of 81 females and 72 males with non-insulin-dependent diabetes were studied. With regard to overall compliance in keeping clinic appointments, 56 (36.6%) patients were still coming in for follow-up 1 year after the diagnosis of diabetes versus 97 (63.4%) patients who had stopped coming in. Overall, 70 (45.8%) patients had a plasma glucose > 180 mg/dL and had not achieved metabolic control, and 83 (54.2%) patients had a plasma glucose < or = 180 mg/dL and had achieved good metabolic control at their last visit. Most patients with good control (58/153, 69.9%) had stopped coming in by the end of 1 year. Only 25 patients with plasma glucose < or = 180 mg/dL were still coming in for follow-up visits, representing the smallest percentage (16.3%) of the total population studied. At 1 year there also was a correlation between increased body weight and improved glycemic control.

Adult↗
PubMedDate not supplied

Sleep deprivation and resident performance.

Cognitive and complex motor performance may be impaired by extended sleep deprivation, but objective data concerning the effects in residents of the sleep deprivation engendered by usual hospital on-call schedules are scant and conflicting. We studied three cohorts of surgical residents (N = 26) who were on call every other night. Each resident kept a sleep diary, gave a self-assessment of motivation and fatigue, and underwent a battery of psychometric tests each morning for 18 or 19 days. The psychometric tests measured cognition, discernment, visual and auditory vigilance, and rapid eye-hand coordination. Sleep deprivation was defined as the lack of four hours of continuous sleep during the preceding 24 hours, and it occurred during 89% of the on-call nights. Daily testing in a repeated-measures design allowed each participant to serve as his or her own control. Sleep deprivation did not affect overall cognitive or motor performance. Further analysis of the correlation between sleep parameters (total sleep and longest uninterrupted sleep interval) and performance on each component of the psychometric test battery identified changes in performance on some tests but only trivial effects due to sleep. The assumption that sleep deprivation associated with usual on-call schedules impairs cognitive and motor performance of residents such that clinical care of patients may be compromised is not supported by our observations.

Adult↗