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Biomedical subjects

M B Jones

Publications and source records attributed to M B Jones.

At least 127 records · Page 7Linked to original sources
PubMed1973

Periodic hypokalaemic paralysis, adrenal adenoma, and normal colonic transport of sodium and potassium.

A 47-year-old woman was cured of hypokalaemia and recurrent paralysis by the excision of an adrenal adenoma. Hypertension was initially ameliorated but was not cured. Suppression of plasma renin activity was abolished when the adenoma was excised. Repeated measurement of plasma corticosteroids before operation showed a slight increase in aldosterone and normal plasma concentrations of deoxycorticosterone, corticosterone, and cortisol. No evidence of excess mineralocorticoid was obtained from measurement of the electrolyte composition of colonic fluid or of rectal potential difference, although both these variables responded normally to salt depletion and exogenous aldosterone. The diagnostic importance of the paradoxically normal colonic measurements is emphasized and the possibility is considered that the adenoma may have secreted an unidentified hormone.

Adenoma↗
PubMed1969

Size discrimination on the skin.

Reasons are given for rejecting the two-point threshold as the standard measure of spatiotactile resolution. As alternative techniques, thresholds were obtained for disc-size and disc-annulus discriminations. Disc-annulus thresholds are comparable to two-point values, but disc-size thresholds are smaller by a factor of 10. Thus, at least part of the cutaneous system is better organized for localization and sizing of a stimulus than for detection of discontinuities in it.

Humans↗