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Biomedical subjects

M B Block

Publications and source records attributed to M B Block.

At least 19 recordsLinked to original sources
PubMed1984

Use of multiple regression techniques in determining the surface of the cornea.

Many methods can be used to obtain specific values for relative corneal location. This paper derives a method in which those points can be used to generate a mathematical equation which will accurately describe the patient's corneal topology. After various dimensional methods are discussed, a three-dimensional mathematical method is derived.

Cornea↗
PubMed1979

C-peptide assay.

Explore the source record for details and available documents.

C-Peptide↗
PubMed1977

"Masked" 21-hydroxylase deficiency of the adrenal presenting with gynecomastia and bilateral testicular masses.

An infertile 27 year old man with precocious puberty is described. He presented in adulthood with unilateral and then bilateral gynecomastia, and subsequently testicular tumors developed. An early diagnosis of congenital adrenal hyperplasia would have avoided unnecessary surgery. Initial detailed metabolic evaluation led to the erroneous diagnosis of 11-hydroxylase deficiency because of the presence of an unusual steroid (21-desoxycortisol) in serum which was falsely reported as an increased 11-desoxycortisol (compound S). The observed low urinary pregnanetriol measurements would have supported this diagnosis. Subsequent specific measurements of 21-desoxycortisol established its presence in the serum and its major metabolite, tetrahydro-21-desoxycortisol, in the urine. The unique features in this case of 21-hydroxylase deficiency alert the physician to its unusual clinical presentation and the pitfalls that may be encountered when evaluating adrenal steroidogenesis.

Adrenal Glands↗