Search PubMed⌕ Search

Biomedical subjects

M Asai

Publications and source records attributed to M Asai.

342 records · Page 19Linked to original sources
PubMedDate not supplied

Mucinous carcinoma of the external auditory canal: case report.

An unusual case of a mucinous carcinoma originating from the external auditory canal in a 70-year-old man is described. Multiple metastatic lesions also appeared in the parotid gland. After a local excision of the primary lesion, the tumor was seen to extend anterosuperiorly along the middle cranial cavity dura. The occurrence of this tumor is exceedingly rare, and, to our knowledge, this is the first report of a mucinous carcinoma of the external auditory canal. The clinical pictures of this tumor and the histological findings are discussed with reference to other reports.

Adenocarcinoma, Mucinous↗
PubMedDate not supplied

Habituation and dehabituation of the spinal polysynaptic reflex responses: modification by naloxone and opiates and their anatomical correlates.

The sustained inhibitory action of spinal endorphins could be responsible for the habituation of polysynaptic responses in the spinal cord. To test this hypothesis, acute spinalized unanesthetized cats (decerebrated and curarized) were used. Sural nerve electrical stimulation (0.2 Hz) was provided and a progressive decrease in the reflex response was found. Conversely, the field potential (lamina V) progressively increased during stimulation, reaching its maximum amplitude when ventral root response showed maximum habituation. The administration of naloxone (0.8-10.0 mg/kg) produced dehabituation or prevented habituation. The immunohistological results showed leu-enkephalin-like immunoreactive dot-like structures in close proximity to neurons of laminae VII, VIII and IX in the lumbo-sacral segment of the spinal cord. Our results suggest an involvement of opioid peptides in the habituation process.

Animals↗
PubMedDate not supplied

Is paranoid schizophrenia the most common subtype? Comparison of subtype diagnoses by Japanese and European psychiatrists, using the summaries of the same patients.

We compared the subtype diagnoses of schizophrenia (ICD-10) of 58 Japanese and 61 European psychiatrists matched for clinical experience using 10 case summaries. As a result, there are marked differences between Japanese and European psychiatrists in the mode of subtype diagnoses of schizophrenia rather than in the clinical pictures of the patients themselves; the hebephrenic type (F20.1) was more likely to be diagnosed by Japanese psychiatrists, while the paranoid type (F20.0) was more frequently diagnosed by European psychiatrists. Japanese psychiatrists take into account the patient's age at onset and the clinical course of the disease in identifying the subtype, while European psychiatrists tend to focus on the presenting symptoms, particularly paranoid symptoms.

Adolescent↗
PubMedDate not supplied

Occult thyroid carcinoma manifested as a large mediastinal tumor.

The authors report a rare case of clinically occult thyroid carcinoma that initially manifested as a metastatic mediastinal tumor with tracheal stenosis. A curative operation was performed by complete removal of the tumor through a median sternotomy approach combined with resection of the tracheal invasion. Histopathological examination revealed transition of a well-differentiated papillary carcinoma into a poorly differentiated component in the lesion invading the trachea, which suggested that this transition might have rendered the tumor more aggressive, leading to tracheal invasion.

Adenocarcinoma, Papillary↗
PubMedDate not supplied

Intraarterial digital subtraction angiography for definitive diagnosis of intracranial aneurysms.

Comparisons between digital subtraction angiography and conventional angiography have frequently been made in the radiologic literature, and the high quality and several advantages of the former have been reported. In this study, 101 patients with intracranial aneurysms were examined only by intraarterial digital subtraction angiography; no conventional angiography was used. High-quality images were consistently obtained, facilitating an accurate and definitive diagnosis of intracranial aneurysm. Magnification radiography and stereography using intraarterial digital subtraction angiography were done to obtain a more precise diagnosis. Five small intracranial aneurysms with diameters of 1.0 to 2.0 mm could be detected. The procedure was considered to be as reliable and as safe as conventional angiography, used previously. Important advantages of intraarterial digital subtraction angiography include reduced procedural time and decreased contrast agent burden, factors that will ensure broader application of this procedure for definitive diagnosis of intracranial aneurysms as experience with the technique accumulates.

Adult↗