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Biomedical subjects

M Armijo

Publications and source records attributed to M Armijo.

At least 37 records · Page 2Linked to original sources
PubMed1990

'Flagellate' erythema from bleomycin. With histopathological findings suggestive of inflammatory oncotaxis.

A case of erythema in a 'flagellate' pattern due to administration of bleomycin in a patient with Hodgkin's disease is described. Emphasis is placed on the low dose of bleomycin administered--15 mg parenterally--and the short time interval between drug administration and beginning of symptoms: 24 h. The histopathological findings were consistent with a mechanism of inflammatory oncotaxis: the attraction of tumor cells by the skin perhaps due to the bleomycin accumulated and the trauma caused by scratching subsequent to pruritus.

Adult↗
PubMed1987

Effect of etersalate on human platelet responsiveness. A study in healthy volunteers.

Ex vivo antiplatelet properties of 2-(p-acetamido-phenoxy)ethyl-o-acetoxybenzoate (etersalate, Daital) and its effects on serum thromboxane A2 (TXA2) levels and prostaglandin I2 (PGI2) generation were studied in human volunteers at two levels of oral dosing. Etersalate inhibited at the lower dosage platelet function and decreased TXA2 levels, but PGI2 generation from rat aortic rings was stimulated when incubated with plasma from etersalate-treated donors. Blood coagulation parameters remained within normal values. It is suggested that etersalate administration could act on platelet arachidonate metabolism at a different level than that of the cyclooxygenase pathway.

Acetanilides↗
PubMed1987

[Epithelioid sarcoma].

A description is given of an epithelioid sarcoma observed in a male patient of 71 years of age. This two-year growth was located in the right leg and presented a clinical picture of a hard walled ulcer. After having been removed surgically the tumour reappeared after seven months at which point amputation was practised at the middle thigh. The patient died twelve months after amputation suffering from pleuropulmonary metastasis. An necropsy was not carried out. The finding of massive arterial neoplastic thrombosis in the histological study confirms the fatal outcome of the patient. The clinical, histological, evolutive and therapeutic characteristics of the epithelioid sarcoma are reviewed.

Aged↗
PubMed1986

[Nevus on nevus. Apropos of 7 case reports, 3 of them associated with other dysplasias, and 1 with an invasive malignant melanoma].

There is some doubt as to whether naevus pilus is identical with naevus-on-naevus or lentiginous naevus en mottes. The former could be classified together with Becker's naevus among the clinically progressive types of epidermal naevi, whereas the latter could be a truly melanocytic naevus of special expression which, for some authors, might become malignant. Seven cases of naevus-on-naevus with different sizes and locations are reported. In 3 cases the naevus was associated with other pathologies: pigmented sclerotic and kyphoscoliosis, verrucoid epidermal naevus, tuberous angioma and underlying muscular hypertrophy. In every case the diagnosis was confirmed by histological examination. An invasive malignant melanoma on superficial extensive melanoma coexisted with a retiform intradermal naevus pilosus. The hypothesis of complex neuro-ectodermic dysplasia and the histogenesis of malignant melanoma developed upon a naevus-on-naevus are discussed.

Adult↗
PubMed1985

Unilateral facial circumscribed hyperhidrosis.

A case of a 15-year-old male with unilateral facial circumscribed hyperhidrosis is reported. No morphological anomalies of the eccrine sweat glands could be noted. The results obtained with local applications of aluminium hexachloride in 20% alcoholic solution are discussed together with the few previous cases appearing in the literature.

Adolescent↗
PubMed1985

[Cutaneomucous hyalinosis in monozygotic twins].

Two Urbach-Wiethe disease cases in both univitelline twins sisters, 8 years old, are presented. Consanguinity is demonstrated in their parents and we consider this to be the second study of this type described in Spain and the first one in the world with such genetic features. We emphasize the early process apparition--just after birth--clinically characterised only by hoarseness. In consecutive years, both sisters developed varioliform scars on elbows, knees, and forehead and induration of lips on their mucous surface and palpebral margins. The histological and ultrastructural findings superposed in both patient--typical and confirmatory of the clinical picture--are commented as well as present histopathogenetic interpretations.

Basement Membrane↗
PubMed1983

Papillon-Lefèvre syndrome. Report of a case treated with oral retinoid RO 10-9359.

We report a case of Papillon-Lefèvre syndrome in a patient aged 26 in whom the familial genetic study showed close consanguinity among the parents. Oral treatment with aromatic retinoid during 6 weeks provided nearly total healing of the cutaneous lesions. Among the explorations carried out, attention must be paid to the lessening of chemotactic factors in the blood serum. Throughout his life, the patient suffered pronounced bacterial infectious processes, the last being especially severe and leading rapidly to death.

Adult↗
PubMed1981

Mucoid cysts of the fingers. Differential diagnosis, ultrastructure, and surgical treatment.

The title "digital mucoid cyst" is generic and encompasses cutaneous myxomas, which are focal intradermic mucinoses that are at times cystic, and ganglia, which are subcutaneous teno-arthro-synovial "hernias." A large myxoma over the second and third phalanges of the middle finger of the left hand is reported that caused progressive functional incapacity. It was managed by surgery, the technique of which is described. The need to differentiate cutaneous myxomas from ganglia is emphasized because the treatment of them is different.

Adult↗
PubMed1980

Effect of indomethacin on the cyclic AMP-dependent protein kinase.

Indomethacin inhibited cyclic AMP-dependent protein kinase activity in small intestine in in vivo experiments. An inverse pattern of variation was exhibited by acetyl salicylic acid, eterylate and benorylate, acetyl-p-amino-phenol being inactive. Indomethacin, acetyl salicylic acid, eterylate and benorylate increased the protein kinase activity in liver, lung and heart after in vivo administration. The in vivo effect of indomethacin was confirmed by in vitro experiments with small intestine and heart protein kinases. These results support the concept that indomethacin can affect protein kinase activity in a tissue-specific way.

Animals↗
PubMed1980

Electrical burns.

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Burns, Electric↗