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Biomedical subjects

M Arlot

Publications and source records attributed to M Arlot.

43 records · Page 3Linked to original sources
PubMedDate not supplied

[The average thickness of trabecular osteons in the iliac crest in normal subjects].

The mean wall thickness (MWT), measured by the Kragstrup technique, and the trabecular bone volume (TBV), have been measured in 50 transiliac undecalcified bone biopsies performed in 50 subjects who died suddenly (traffic accident, carbon monoxide, poisoning). Diseases affecting the skeleton were excluded in the autopsies. Our values for MWT were similar to those found in previously published studies except those of Kragstrup's group, in which values are higher. As our measuring technique was that of Kragstrup, these results could be explained either by a difference in staining methods (Solocromo cyanine R and Goldner method respectively) or by the differences in populations considered (French and Danish respectively). Our study confirmed a significant decrease in MWT and TBV with age and a positive correlation between MWT, TBV and age.

Adolescent↗
PubMedDate not supplied

Macroscopically normal cartilage from the human osteoarthritis femoral head. I. Histological evaluation.

Thirty-five macroscopically "normal" cartilage specimens from 32 osteoarthritic (OA) femoral heads removed surgically were histologically analyzed, and found to be composed of both normal and abnormal cartilage. The latter showed either middle tissue layer alterations or invasion by new tissues of extracartilaginous origin. Middle cartilage layer alterations consisted of unmasked fibers and loss of matrix staining with alcian blue and were found to be closely related to the development of new osteophytic tissues. Thus in OA the appearance to the naked eye of normal cartilage is inappropriate for valid biochemical studies, and a microscopic control of "normal tissue" appears to be necessary for any study of early cartilage changes in OA.

Adult↗
PubMedDate not supplied

Macroscopically normal cartilage from the human osteoarthritic femoral head. II. Measurement of cartilage thickness and cell density.

Cell density and thickness of macroscopically "normal" cartilage from 32 osteoarthritic (OA) femoral heads removed surgically have been studied by using histomorphometry. The results have been interpreted with special reference to qualitative aspects of regions analyzed at a microscopic level. OA cartilage with a microscopically normal appearance have a normal cell content and thickness except for the region adjacent to the zone of cartilage cleavage where a significant reduction in superficial cell density was found. OA cartilage showing middle tissue layer lesions such as unmasked fibers was characterized by an almost normal cellularity but a significantly increased tissue thickness.

Cartilage↗
PubMedDate not supplied

The cell density of human femoral head cartilage.

The human femoral head cartilage in 63 subjects with ages ranging from 16 to 100 years demonstrates that in the course of aging the cell density of the whole cartilage thickness decreases about 40 per cent. The reduction of the cellularity with age is more accentuated in the superficial than in the deeper zone and is even limited to the superficial zone during the latter part of aging. Proportionately the cell loss is similar in the superior and inferior poles of femoral head suggesting a uniform distribution of age related changes. In absolute value, the decrease of the superficial cell density is much higher in the inferior than in the superior pole; the decrease may be related to the propensity of this region to fibrillation.

Adolescent↗