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Biomedical subjects

M Arif

Publications and source records attributed to M Arif.

85 records · Page 5Linked to original sources
PubMed1984

Phaeochromocytoma.

Explore the source record for details and available documents.

Adrenal Gland Neoplasms↗
PubMed1983

A randomized, double-blind, parallel group comparison of disopyramide phosphate and quinidine in patients with cardiac arrhythmias.

This report summarizes the results of a randomized, double-blind, parallel group, multicenter study which compared the antiarrhythmic activity and safety of oral disopyramide phosphate and oral quinidine sulfate. A total of 124 outpatients, whose pretreatment rates of ventricular and/or supraventricular arrhythmias were documented by ambulatory ECG recordings, were randomly assigned to receive either oral disopyramide or oral quinidine for the eight-week course of the study. Every two weeks, ten-hour ambulatory ECG recordings were obtained from each patient and blood was drawn to determine serum concentrations of assigned drug.

Administration, Oral↗
PubMed1983

Metamorphic changes in the neurosecretory cells of Diacrisia obliqua Walker (Lepidoptera: Arctiidae).

4 PF-positive NSC appear for the first time in each brain hemisphere on 4th day of exclosion. B-, C- and D-cells appear in the pars intercerebralis region on the second day in the 2nd instar. 3 lateral NSC appear for the first time in this instar. 2 A4-cells appear in the tritocerebral region of the 4th instar. An increase in the number and size of the NSC is noted in the successive instars. A3-cells appear for the first time in 5th instar. The secretory phases in the pupal period are completed in three "stages" which last for 3.3 and 4 days respectively. Adults lack PF-positive cells in the lateral and tritocerebral regions. Females show accumulation of NSM before mating which depletes gradually as the mating time reaches.

Animals↗
PubMed1983

Metamorphic changes in the cephalic neurosecretory cells and the retrocerebral neuroendocrine complex of Pericalia ricini Fabricius (Lepidoptera: Arctidae).

Aldehyde Fuchsin-positive (AF-positive) A-cells first appear in the pars intercerebralis of 4d old 1st instar larva. First sign of secretory activity is noted in 3d old 2nd instar. A gradual increase in the number of neurosecretory cells (NSC) is noted during successive larval instars. The secretion of neurosecretory material (NSM) is followed by the coalescence and finally release phases. This is a regular phenomenon, however, various NSC exhibit different phases of secretory activities at a particular time. In 4d old pupa, A4 and D-cells are absent in the tritocerebral region and in 7d, decrease in the number and size of AF-positive cells is noted. In 4-7d old pupae A4-cells are absent in the lateral region but are present in 8-10d old pupae. In unmated females 6A4-cells are present in the lateral region of the brain which are absent in unmated males. The optic region of unmated males and females have A4 and B2-cells whereas A2-cells are absent in the tritocerebrum of both the sexes. The total number of NSC in females is more than males. A1 and A3-cells of mated males and all the NSC of laid females lack NSM.

Animals↗
PubMed1980

Atrioventricular sequential pacemakers: indications, complications, and long-term follow-up.

Our experience with 32 patients with atrioventricular (AV) sequential pacemakers and an average follow-up of 22 months is presented. The pertinent literature and physiology are reviewed. The indications, advantages, and complications of AV sequential pacemakers are analyzed. Half of the patients required bifocal pacing for control of arrhythmia alone, while half required control of arrhythmia associated with congestive heart failure due primarily to a noncompliant left ventricle. It is anticipated that the hemodynamic improvement occurring as a results of AV sequential pacing will increase the use of this mode of cardiac pacing in selected patients.

Adult↗
PubMedDate not supplied

Baseline seroepidemiology of hepatitis B virus infection in two Saudi high-risk groups: patients on haemodialysis and patients with congenital bleeding disorders.

Because background seroepidemiological data are required before nationwide vaccination against hepatitis B virus (HBV) is attempted, the rate of exposure to HBV was investigated in two high-risk Saudi groups: patients on haemodialysis and patients with congenital bleeding disorders. Although the HBsAg carrier rate was higher in patients with congenital bleeding disorders (11.1%) than in patients on haemodialysis (4.6%), the exposure rate to HBV was similar in both groups (38.8%-44.5%). Because of this high exposure rate it seems cost-effective, at least in the Saudi population or in countries which are endemic for HBV, to screen for HBV markers before vaccination against HBV is recommended.

Adult↗
PubMedDate not supplied

Isolation of enterovirus 70 (EV70) from patients with acute haemorrhagic conjunctivitis in two areas of Saudi Arabia.

This is the first epidemic of acute haemorrhagic conjunctivitis (AHC) reported from Saudi Arabia in which enterovirus 70 (EV70) was implicated as aetiological agent. EV70 was isolated from 5 of 29 conjunctival scrapings from patients with AHC. Two human diploid cell lines, human skin fibroblast (HSF) and human embryonic lung fibroblast (MRC-5), were quite sensitive for the isolation of this virus. The relatively high isolation rate could also be attributed to the timing of collection of specimens and perhaps to the fact that conjunctival scrapings contained more virus particles than did eye swabs.

Adolescent↗
PubMedDate not supplied

Possible aetiological role of hepatitis E virus in acute non-A, non-B, non-C hepatitis in Saudi Arabia.

During a period of 10 months, 69 Saudi Arabian patients (14 children and 55 adults) were diagnosed as having acute non-A, non-B, non-C (NA, B, C) hepatitis at King Khalid University Hospital, Riyadh, Saudi Arabia. Seven of the paediatric patients had anti-hepatitis E virus (HEV) immunoglobulin (Ig) M and anti-HEV IgG; 26 adults (47.3%) had anti-HEV IgM and 30 (54.5%) had anti-HEV IgG. These results, together with the fact that none of the 40 patients with acute hepatitis A virus infection, none of the 24 with hepatitis B virus, and none of the 30 with acute hepatitis C virus, had anti-HEV IgM, indicates that HEV is an important aetiological agent for acute NA, B, C hepatitis in Saudi Arabia, and that there are still other unidentified agent(s) responsible for acute hepatitis in Saudi Arabia.

Adolescent↗
PubMedDate not supplied

Immunity to potato mop-top virus in Nicotiana benthamiana plants expressing the coat protein gene is effective against fungal inoculation of the virus.

Nicotiana benthamiana stem tissue was transformed with Agrobacterium tumefaciens harboring a binary vector containing the potato mop-top virus (PMTV) coat protein (CP) gene. PMTV CP was expressed in large amounts in some of the primary transformants. The five transgenic lines which produced the most CP were selected for resistance testing. Flowers on transformed plants were allowed to self-fertilize. Transgenic seedlings selected from the T1 seed were mechanically inoculated with two strains of PMTV. Virus multiplication, assayed by infectivity, was detected in only one transgenic plant of 98 inoculated. T1 plants were also highly resistant to graft inoculation; PMTV multiplied in only one plant of 45 inoculated. Transgenic T1 seedlings were challenged in a bait test in which they were grown in soil containing viruliferous spores of the vector fungus Spongospora subterranea. In these tests only two plants out of 99 became infected. Of the five transgenic lines tested, plants of three lines were immune to infection following manual, graft, or fungal inoculation.

Base Sequence↗
PubMedDate not supplied

Spot size and quality of scanning laser correction of higher order wavefront aberrations.

PURPOSE: To investigate the effect of laser spot size on the outcome of aberration correction with scanning laser corneal ablation. METHODS: Numerical simulation of ablation outcome. RESULTS: Correction of wavefront aberrations of Zernike modes from second to eighth order were simulated. Gaussian and top-hat beams of 0.6 to 2.0-mm full-width-half-maximum diameters were modeled. The fractional correction and secondary aberration (distortion) were evaluated. Using a distortion/correction ratio of less than 0.5 as a cutoff for adequate performance, we found that a 2 mm or smaller beam is adequate for spherocylindrical correction (Zernike second order), a 1 mm or smaller beam is adequate for correction of up to fourth order Zernike modes, and a 0.6 mm or smaller beam is adequate for correction of up to sixth order Zernike modes. CONCLUSIONS: Since ocular aberrations above Zernike fourth order are relatively insignificant, current scanning lasers with a beam diameter of 1 mm or less are theoretically capable of eliminating most of the higher order aberrations of the eye.

Computer Simulation↗