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Biomedical subjects

M Arborelius

Publications and source records attributed to M Arborelius.

At least 73 records · Page 4Linked to original sources
PubMed1978

Duodenal motility pattern in duodenal ulcer disease.

The motility in the first part of the duodenum has been studied by a method combining roentgen fluorography and multiple pressure recordings in 7 normal volunteers, in 7 patients having gastric, and in 7 having duodenal, ulcer. A significantly lower number of retrograde motor sequences was found in cases with duodenal ulcer than in normals, while patients with gastric ulcers showed no such difference. This abnormality in subjects with duodenal ulcer was interpreted as a deficiency in the transport of neutralized duodenal contents from more distal parts of the duodenum up into the bulb. The abnormality can explain the earlier known lower pH in the duodenal bulb in subjects with duodenal ulcer and contribute to the pathogenesis of the disease.

Duodenal Ulcer↗
PubMed1977

Arterial-venous differences across the lungs in plasma triglyceride concentration.

Arterial-venous differences in plasma triglyceride across the lungs were determined in healthy human subjects before, during and following infusion of a soybean oil emulsion into the superior vena cava. Samples were acquired from the pulmonary and brachial arteries. A significantly greater mean concentration of triglyceride in venous as opposed to arterial blood was evident following 12 min of infusion (pless than 0.001), with a tendency for the retained lipid to be released during the postinfusion period. It could be calculated that during infusion the lungs retained about 20% of the available triglyceride, or 3 mmol/min.

Adult↗
PubMed1977

[Pathophysiology after resections of the lung (author's transl)].

Measures of preventing postoperative lung atelectasis are discussed. The importance of total pre-operative smoking prohibition is stressed. Formula for pre-operative prediction of postoperative ventilation and pulmonary artery pressure are presented. Lung distention is not to be compared to lung emphysema. Lung distention may even improve ventilation as well as circulation of the remaining lung tissue.

Adult↗
PubMed1975

Respiratory function in esophageal hiatus hernia. I. Spirometry, gas distribution, and arterial blood gases.

As a part of a preoperative investigation, spirometry and blood gas tensions were studied in 64 subjects with X-ray-verified hiatus hernia (34 sliding, 22 mixed, and 8 of paraesophageal variety). According to the transverse diameter of the hernia. They were divided into 3 groups, small (2-5.9 cm), medium (6-9.9 cm), and large (10-17 cm) hernias. No correlation between the size of the hernia, reflux incidence, and spirometric findings could be demonstrated. A significant reduction of the arterial oxygen tension was found in small hernias and in vital capacity and maximal voluntary ventilation (MVV) in medium-sized hernias. Significant reduction in MVV was noted in the large hernia group. A common spirometric finding in all groups was a significant increase in residual volume and wash-out volume. The incidence of restrictive or obstructive pulmonary impairment was high in large (39%) and small (32%) hernias and relatively low in medium-sized hernias (8%). Roentgenological fibrosis was not found in any of the patients, while 4 showed emphysematous changes.

Adult↗
PubMed1975

Respiratory function in esophageal hiatus hernia. II. Regional lung function.

64 subjects with hiatus hernia (34 sliding, 22 mixed, and 8 of paraesophageal variety) were divided into 3 groups according to the transverse diameter of the thoracic loculus and examined by 133Xe-radio-spirometry in the supine position. 48 subjects (22 sliding, 18 mixed, and 8 or paraesophageal variety) showed a significant reduction in the regional ventilation, perfusion or lung volume. Significant correlations were found between the diameter of the thoracic loculus and the reduction in these vairables of the affected lung.

Adult↗
PubMed1975

Regional and total lung function studies in patients with hemidiaphragmatic paralysis.

Global and regional lung function were studied in 17 subjects with hemidiaphragmatic paralysis. Global lung function (VC, MVV, and FEV1) in the sitting postion was reduced by an average of about 25%. Regional lung function data in the same position showed a considerable decrease in perfusion (19%), ventilation (20%), and lung volume (7%) of the diseased side as compared to reference values obtained in healthy volunteers. Compared to the partition of function in the supine, the perfusion of the affected lung increased when it was lowermost in the lateral decubitus postion, while regional FRC decreased and ventilation changed little. When uppermost, perfusion and ventilation of the affected lung decreased while FRCr increased somewhat. The arterial oxygen tension was significantly below normal in the supine position but in the normal range in the sitting position. It increased further during exercise. Bronchography showed compression of the basal lung segments on the affected side in the erect, and kinking and obliteration of lower lobe bronchi in the supine position and still more when the lung was lowermost in the lateral decubitus position.

Activities of Daily Living↗
PubMed1975

Influence of a fatty acid on duodenal motility.

The duodenal transport mechanism has been studied by a method combining roentgen-fluorography and multiple pressure recordings. Three main types of motility were distinguished: propulsive, retrograde, and static. The motor pattern in the first part of the duodenum was studied in 15 individuals under basal condition and after application in the duodenal lumen of sodium myristate. The resulting inhibition of gastric emptying was found to be correlated to a significant inhibition of the propulsive movements in the duodenum. The two others types of motor activity did not change significantly.

Depression, Chemical↗
PubMed1975

Predominantly unilateral asthma studied with 133Xe-radiospirometry.

Regional lung function in the supine position was studied with 133Xe-radiospirometry in 10 asthmatic subjects in remission, before and after inhalation of specific allergens in the right lateral decubitus position. Regional ventilation and regional lung volume showed a significant decrease in the right lung. The decrease in ventilation was most pronounced in the diaphragmatic half of the lung. The regional perfusion of the right lung decreased less than the ventilation. The change in perfusion, however, became greater with time, whereas the decrease in ventilation remained the same as shortly after the provocation. Predominantly regional asthma could thus be provoked in the regions that receive most of the allergen in the right lateral position. The asthma was easily controlled and caused little discomfort.

Adolescent↗