[A weekday hospital unit in hepatology].
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Hospital Departments↗
Biomedical subjects
M Angelini
Publications and source records attributed to M Angelini.
Abnormalities of sex hormones in men with systemic lupus erythematosus.
Sex hormone concentrations were studied in 10 men with systemic lupus erythematosus (SLE) before and after HCG stimulation and compared with those of 10 healthy volunteers. The SLE men had significantly lower testosterone/estradiol ratios (before HCG test) and significantly lower mean increases in testosterone after HCG stimulation than the normals. Our findings confirm that there are sexual hormone abnormalities in SLE and suggest that these abnormal patterns may be important in the modulation of immune responses in SLE.
Adult↗
[Acupuncture in rheumatology. Case contribution].
Results obtained by acupuncture treatment of patients with rheumatic diseases were analysed. Clinical, serological and psychological parameters were evaluated at the beginning and end of treatment. Results showed variations in pain intensity, articular function, inflammation, anxiety and bodily condition. The results are accompanied by a description of the limits of the research conducted.
Acupuncture Therapy↗
A new rheometer with special features designed for bronchial mucus analysis in clinical practice.
Changes in production and in physico-chemical properties of bronchial mucus is a common denominator of many pulmonary diseases. A rheometer with innovative features aimed at bronchial mucus routine investigation in clinical practice at the bedside of the patient has been designed. Searle-type configuration with a coaxial cylinder sensor system and the Mooney-Ewart geometry has been adopted. Another new feature is that bob and cup are disposable. Dynamic viscoelasticity is calculated through a microprocessor with specific software and by means of a magnetic torque--motor electronically driven by the microprocessor. The self-zeroing procedure and the autorange greatly simplify the measuring-cycle which is driven by only one switch. Data (eta and G') are automatically printed on paper. The whole measuring-cycle at the bedside of the patient takes 3-5 min, so that in 1h about 12 samples can be investigated.
Bronchi↗
[A case of thymoma: histological and diagnostic aspects and surgical considerations].
The histological and diagnostic features of a thymoma case observed recently have been investigated in the present study. Comparing the case under investigation with the literature, the Authors conclude that the proper surgical approach is that indicated by Jaretsky. By means of a longitudinal sternotomy associated with minimal cervical incision, the whole mediastinal cellular tissue together with that of the thyroid inferior poles is easily removed. Moreover oncological and myastenic recurrences have a very low incidence in cases surgically treated with this procedure.
Aged↗
Neuroendocrine tumors of the gastroenteric canal. Anatomopathological and diagnostic-therapeutic definition. Description of a case with a rare cecal localisation.
The authors take the case of a neuroendocrine tumour of the cecum as the starting point for an analysis of the anatomopathological and diagnostic-therapeutic aspects of these neoplasms. Furthermore, the authors underline that neuroendocrine tumours (NET) of the colon represent an extremely rare nosological entity and that they are heterogeneous from a clinical and biochemical point of view, thus making a reliable preoperative diagnosis a problem that is still difficult to resolve today.
Cecal Neoplasms↗
Fine needle aspiration and core needle biopsy techniques in the diagnosis of nodular thyroid pathologies.
It is widly accepted that Fine Needle Aspiration Biopsy (FNAB) is the main test to distinguish benign from malignant thyroid lesions. Nevertheless, this technique presents some limits such as the possibility of false-negative or inadequate samples and it is unable to cytologically discriminate among adenomathosus goiter, follicular adenoma and well-differentiated follicular carcinoma. The aim of this study was to evaluate the possibility of restricting these limitations using Core Needle biopsy (CN) technique. Therefore we selected for CN, 40 out of 136 patients who underwent FNAB during a one year period; among these patients only 32 agreed a to this technique. Forty-two out of 136 patients underwent surgery; 29 of them were subjected to both biopsies. Sixteen of the diagnostic microbiopsies have been histologically confirmed. We had no discordant cases between cytological and microhistological diagnosis, except for one case which appeared cytologically colloid goiter, microhistologically follicular neoplasm and histologically follicular adenoma. In this case it was not possible to microhistologically discriminate benign from malign follicular lesion. In our experience not all patients accepted CN biopsy as well as FNAB and, moreover, this technique showed no advantage over FNAB diagnosis. On this base we think that actually FNAB should be the main procedure in the diagnosis of the thyroid lesions. It is easily performed, accepted by the patients and has a low cost-benefit ratio. If the sample is not diagnostic it can be easily repeated and false-negative cases could be discovered thanks to an adequate clinical and ultrasonographical follow-up of the patients.
Adenocarcinoma, Follicular↗
Surgical treatment of multinodular goiter: incidence of lesions of the recurrent nerves after total thyroidectomy.
The problems concerning surgical goiter treatment are discussed, particularly the morbidity of total thyroidectomy and possible injury to recurrent nerves in comparison to the partial resection of the gland. We discuss our case material and review the literature. We conclude that total thyroidectomy seems to be the most effective surgical procedure with lower morbidity than subtotal thyroidectomy.
Adolescent↗
The possible role of collagen fibril dysplasia in the pathogenesis of cartilage damage in rheumatoid arthritis.
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Arthritis, Rheumatoid↗
The role of collagen fibrils in the pathogenesis of osteoarthrosis.
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Adult↗
[Comparative study of the effectiveness of imipenem versus ceftazidime and ceftriaxone in the prevention of postoperative infections].
A comparative study was performed on the efficacy, safety and tolerability of three different antibiotics (imipenem, ceftazidime, ceftriaxone) in the prevention of postoperative infection. Evaluations were made on the basis of the results obtained in a group of 90 patients subdivided into three matched groups each of which was treated with one of the three compounds. The trend of cutaneous temperature showed differences at the limit of significance (p congruent to 0.05). Variations in leucocyte concentrations showed an analogous pattern in all patients, although there were fewer and with a shorter duration in subjects treated with imipenem. The wound healing process was improved in patients receiving prophylactic antibiotic treatment in the form of imipenem (0.01 < p < 0.05) who also showed a greater respect for therapeutic protocols (80%), a higher percentage of remission of fever and a shorter mean hospital stay (9 days). In the light of these preliminary results the authors express their favourable judgement regarding the choice of imipenem for the prophylaxis of postoperative infection; however, each of the three protocols showed a considerable prophylactic capacity as well as good tolerability and ease of use.
Adult↗
[Laparoscopic treatment of acute cholecystitis. Personal experience and preliminary results].
At the beginning of their experience the authors limited laparoscopic treatment to simple cholelithiasis. They then extended this method to acute cholecystitis. They report here 11 cases with no mortality and morbidity and a conversion rate equal to 18.18% (2 cases of new acute phase of chronic cholecystitis after deferred emergency surgical treatment). The postoperative stay in hospital never exceeded 72 hours for the 9 cases of laparoscopic cholecystectomy, while the 2 cases of laparotomic respectively on the VII and VIII days. In consideration of what is reported in the literature and of personal experience, even if limited, the authors acknowledge that laparoscopic cholecystectomy if it is practised by an expert surgeon in the presence of precise indications and with a low conversion rate.
Acute Disease↗
[Laparoscopic appendicectomy. Personal experience and results].
The paper discusses the indications, limits and basic technical principles of laparoscopic appendicectomy, comparing the costs and benefits to the laparotomic method. The authors review the Literature on this subject and report their personal experience of 11 cases with a nil morbidity and mortality rate.
Adult↗
[Adrenal cysts. Description of a clinical case].
Starting from the study of a personal case, the authors underline that adrenal cysts are a very rare pathology, occasionally observed and without symptoms. Moreover they point out diagnostic methods, don't permit a certain diagnosis and therapies are not univocal.
Adrenal Gland Diseases↗
[Experience at an ambulatory surgical service for thyroid diseases].
Based of a personal series of 206 patients, the authors evaluate their personal experience of an outpatient surgery ward for thyroid pathologies. The paper reports the diagnostic and therapeutic approaches both in patients undergoing surgery and those who do not. Attention is focused on the importance of the multidisciplinary team and the quality of the results of a homogeneous follow-up.
Adult↗