Search PubMed⌕ Search

Biomedical subjects

M Amato

Publications and source records attributed to M Amato.

At least 199 records · Page 11Linked to original sources
PubMedDate not supplied

[Efficacy of intensive blue double-lamp phototherapy in the treatment of ABO incompatibility and idiopathic severe hemolytic jaundice].

Blue phototherapy is now generally accepted to be effective in the management of neonatal hyperbilirubinaemia. The response to phototherapy increases with increasing the skin surface area exposed to fluorescent illumination. We investigate the effects of "Intensive double direction phototherapy" (Double blue light 2 X 30 microW/cm2) in the treatment of neonatal hyperbilirubinaemia of 42 infants with ABO haemolytic diseases and "idiopathic" jaundice. We have found that serum bilirubin levels in newborn infants may be controlled more effectively with double light treatment and that the number of exchange transfusions was reduced.

ABO Blood-Group System↗
PubMedDate not supplied

[Prevention of hyaline membrane disease by intraamniotic administration of thyroxine].

The best management of respiratory distress syndrome (RDS) is prevention. Prenatal administration of Cortico-steroids has been proved to be a valuable way for accelerating fetal lung maturation. In case of high risk pregnancy, however, where acceleration of lung maturation is most needed, there may be a relative contraindication for using steroids. According to the theory that the increase in the phospholipid component of surfactant may be mediated by intra-amniotic thyroxin administration, its use for accelerating human fetal lung maturation has been tested. Seven samples of amniotic fluid were obtained in order to determine the lung maturity in seven pathological pregnancies (pre-eclamptic toxemia, diabetes, infection, hypertension, placental insufficiency) prior to elective caesarean section. Since thyroxin does not cross the placenta, it has to be injected directly into the amniotic sac. 20 ml of clear fluid were obtained by amniocentesis prior to each injection of 250 micrograms of Levothyroxin through the same needle. Each of the infants was delivered before 34 weeks. Birth weights of the premature infants were between 1220-1870 grams. In all cases the Lecithin/Sphingomyelin Ratio (L/S) in amniotic fluid analysis was immature. After thyroxin administration L/S Ratio was mature in pharyngeal aspirate examination after delivery in 6 cases. RDS was seen in only one infant. The interval between intraamniotic administration of T4 and delivery ranged from 72 hours to 2 weeks in 6 cases. In one case with clinical and radiological signs of RDS the injection-delivery interval was less than 48 hours: the L/S Ratio in pharyngeal aspirate was immature 2,8 (normal greater than 3).(ABSTRACT TRUNCATED AT 250 WORDS)

Amnion↗
PubMedDate not supplied

[Candida sepsis in premature newborns].

The incidence of candida septicemia in the neonatal period is increasing. We report a case of a preterm baby with acute anuric renal failure resulting from systemic candidiasis and we discuss of pathogenic factors, diagnosis and modern therapy. Prompt and opportune antimycotic therapy is the only chance for survival. The disease is generally fatal unless treated in time.

Acute Kidney Injury↗
PubMedDate not supplied

[Neonatal mepivacaine poisoning following episiotomy].

Two cases of mepivacaine-intoxication in newborn infants following local anesthesia for maternal episiotomy are presented. The accidental direct injection of local anesthetics into the fetal scalp produce acute drug poisoning in the newborn. Seizures, bradycardia, apnea, hypotonia, loss of pupillary light reflexes are the major manifestations among babies severely poisoned. The early diagnosis and therapy of this syndrome permit a more favorable prognosis without risks of perinatal death or neurologic sequelae.

Apnea↗