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Biomedical subjects

M Altaras

Publications and source records attributed to M Altaras.

At least 55 records · Page 3Linked to original sources
PubMed1987

Subsequent pregnancy following labor of a very-low-birth-weight infant.

During a period of 5 years (1978-1982), 55 mothers with an average age of 27.5 +/- 5.4 years, delivered 59 infants, weighing less than 1500 g. These infants had a mean birth weight of 1160.5 +/- 263 g and a mean gestational age of 28.7 +/- 2.25 weeks (range 25-32 weeks). Subsequently 47 (79.6%) survived and 12 (20.4%) died. There was a statistical difference of both mean gestational age and of mean gestational weight between survivors or infants with neonatal death. Twenty two of 29 mothers who subsequently became pregnant, gave birth to liveborn infants, who subsequently survived (four pregnancies terminated in induced abortion). Mean gestational age was 37 +/- 3 weeks (range 32-41 weeks) (P less than 0.001) and a mean birth weight was 2753.2 +/- 570 g (range 1620-3600 g) (P less than 0.001. All the 22 infants subsequently born weighed more than 1501 g, 7 (31.8%) infants weighed 1501-2500 g and 15 (68.2%) more than 2500 g. Similar data were obtained from a control group of 615 mothers (chosen at random) who delivered a normal infant at term, 202 subsequently became pregnant and 176 gave birth to a normal infant at term. Mean gestational age was 39.54 +/- 1.24 weeks (P less than 0.001) and mean birth weight was 3299.3 +/- 412 g (P less than 0.001). (In the control group 10 pregnancies terminated in induced abortions). The above data could be used in advising for future pregnancy outcome in regard to women with premature births.

Female↗
PubMed1987

Pregnancy with an artificial pacemaker.

Complete heart block in pregnancy is not a common encounter. The first case was reported in 1914 by Nanta and today some 100 cases are documented. Heart block may be congenital or acquired secondary to cardiac surgery, rheumatic heart disease, or infective disorders. Heart block, whether congenital or acquired, rarely creates any special obstetric problems. Today there is an increasing use of cardiac pacemakers in younger people and the first reported obstetric experience with a cardiac pacemaker implanted before pregnancy was by Shouse and Acker. This review will document the course and outcome of all reported pregnancies in women conceiving with an artificial pacemaker, and discuss complications and principles of management. We will also report our experience with a woman suffering from a complete heart block in whom an internal cardiac pacemaker was inserted before pregnancy.

Adult↗
PubMed1986

The use of concomitant chemotherapy and radiotherapy prior to surgery in advanced stage carcinoma of the vulva.

Six cases of primary advanced squamous carcinoma of the vulva were treated with concomitant chemotherapy and radiotherapy (C + RT). In five patients it was given in preparation for surgery. The radiation was delivered to the whole pelvis in 10 equal daily fractions of either 2.0 or 2.5 Gy. Mitomycin C (10 mg/m2) was given on Day 1, and 5-fluorouracil (1,000 mg/m2) was given daily from Days 1 to 4, inclusive. All six patients had satisfactory early tumor response. Three patients received one course of C + RT and three were given two courses. One patient died suddenly of unknown causes 6 days after completing the C + RT. One patient with fixed groin nodes was treated with palliative intent. She maintained a complete local response but died 6 months later of liver metastases. The remaining four patients underwent surgery without healing complications and are alive with no evidence of disease at 1, 4, 14, and 26 months. In our experience vulval carcinomas can be reduced in size and extent by prior chemotherapy and radiotherapy and require less extensive surgery.

Adult↗
PubMed1986

Single- versus multiple-dose mezlocillin prophylaxis in emergency cesarean section.

163 patients undergoing emergency cesarean section were prospectively and randomized evaluated to determine the effect of mezlocillin in reducing postoperative morbidity. We compared a single 5-gram preoperative dose and a perioperative 3-dose regimen, each of 2 g, with a placebo. Postoperative morbidity was reduced from 65% in the placebo group to 20% in the groups receiving mezlocillin (p less than 0.005). The incidences of febrile morbidity, endometritis and urinary tract infection were all significantly lower in both groups given mezlocillin. There was no difference in the reduction of morbidity between the two groups receiving mezlocillin. The main advantages of the prophylaxis included a shorter hospitalization and the absence of serious infections in the treated groups.

Adult↗
PubMed1986

Ultrasonic real-time diagnosis of transitory fetal pleural and pericardial effusion.

Congenital fetal effusions are rare and often fatal. Prenatal ultrasonic diagnosis is an important factor in both diagnosis and management of this condition. We report a case with both pleural and pericardial effusion, the ultrasonic diagnosis and follow-up, and the birth of a healthy baby. A short review of the literature is given.

Adult↗
PubMed1986

Perinatal factors influencing outcome of very-low-birth weight infants.

Of 106 liveborn infants weighing 751 to 1,500 g born to 97 mothers, 97 (91.5%) were transferred to the Neonatal Intensive Care Unit for premature infants at the Beilinson Medical Center, Petah Tikva. Treatment with tocolytic agents (ritodrine) and corticosteroids (betamethasone) was introduced when indicated but no preventive antibiotics were used during the antenatal period. All infants received immediate care by a neonatologist and 77 infants (72.6%) survived. Although the cesarean section deliveries increased during the survey from 21.7% during the first period to 43.3% during the second, there was no statistically significant difference in the survival rate. Thus it seems that there is no advantage in performing cesarean sections for very-low-birth weight infants in either vertex or breech presentations.

Critical Care↗
PubMed1985

Endocervical stromal sarcoma--a case report.

A case of a stromal sarcoma in a cervical polyp is presented. The tumor was confined to the polyp as evidenced by the histological examination of the uterus and cervix after surgery. In spite of that the patient died of widespread abdominal metastasis 1 year after the initial diagnosis.

Female↗
PubMed1985

Prophylactic single-dose co-trimoxazole for prevention of urinary tract infection after abdominal hysterectomy.

The efficacy of a preoperative single-dose of co-trimoxazole in reducing postoperative urinary tract infection and febrile morbidity after abdominal hysterectomy was evaluated in a randomized placebo-controlled study of 90 patients undergoing surgery. Among the co-trimoxazole patients, 6.2% developed urinary tract infection compared to 31% in the placebo group (p less than 0.001) and 12.5% febrile morbidity compared to 38% in the placebo patients (p less than 0.025). No adverse side effects of co-trimoxazole were observed and this regimen seems both safe and effective.

Adult↗
PubMed1985

Neonatal outcome of infants delivered at 26-28 weeks of gestation.

The delivery results of 42 infants born to 40 mothers at the gestational age of 26-28 weeks during a period of 5 years were analyzed. The study was evaluated in two periods of time: in the first period out of 15 infants born only 5 (33.3%) survived, while in the second period 21 (77.7%) out of 27 infants survived (p less than 0.01). 38 infants were transferred to a neonatal intensive care unit for premature infants. Only 41% of the infants transferred in the first period survived, as compared to 80.7% of those transferred during the second period (p less than 0.01). There was no significant difference in the mean birth weight at each gestational age between the survivors and those who subsequently died in both periods of the study. In the study groups, cesarean section rate rose from 13.3% in the first period to 44% in the second. Mode of delivery, regardless of the presenting part, did not seem to influence neonatal survival. Obstetrical management, including the performance of operative delivery for fetal indications and active neonatal resuscitation, seems to be reasonable for infants at the gestational age of 26 weeks or more.

Cesarean Section↗
PubMed1985

Fetal supraventricular tachycardia: prenatal diagnosis and pharmacological reversal of associated hydrops fetalis.

Intrauterine fetal supraventricular tachycardia is a rare condition often associated with the syndrome of nonimmune hydrops fetalis. When the fetus is preterm it is vital to treat the arrhythmia with maternally administered drugs and different regimens have been reported in the literature. We report 1 case of this arrhythmia successfully treated in utero with maternally administered digoxin resulting in complete reversal of the hydrops fetalis and the birth of a healthy baby. A review of the relevant literature is brought forth.

Digoxin↗
PubMed1985

An unusual case of cervical pregnancy.

A very rare case of an unruptured cervical pregnancy, diagnosed by vaginal examination is described. An elective abdominal hysterectomy was performed. No complications related to this entity occurred during treatment. Clinical management and literature are discussed.

Adnexa Uteri↗
PubMed1985

Single-dose mezlocillin prophylaxis in emergency cesarean section.

A single 5-gm dose of mezlocillin or a placebo was administered intravenously 30 minutes before surgery to patients undergoing emergency cesarean section. The assignment of drug or placebo was randomized. Postoperative morbidity occurred in 62.5% of patients receiving placebo and in 18.4% of those receiving mezlocillin (P less than 0.001). The incidences of febrile morbidity, endometritis, and urinary tract infection were significantly lower in the group given mezlocillin. Other benefits of antibiotic prophylaxis included a shorter hospital stay and no serious infections in the group given mezlocillin.

Adult↗
PubMed1984

[Struma ovarii].

Explore the source record for details and available documents.

Adult↗
PubMed1984

Papillary adenofibroma of the endometrium: case report and review of the literature.

A case of papillary adenofibroma of the endometrium is reported in a 78-year-old parous woman. Diagnosis was made by curettage. The patient was treated by total abdominal hysterectomy with bilateral salpingo-oophorectomy. This is the eighth case known in the literature. Clinical and pathological aspects of this relatively new pathological entity are reviewed.

Adenofibroma↗
PubMed1984

Perioperative mezlocillin prophylaxis in cesarean section.

One hundred thirteen patients were prospectively evaluated to determine the prophylactic effect of mezlocillin in women undergoing cesarean section. Subjects received 2 gm of mezlocillin or placebo intravenously 30 minutes before surgery and four and nine hours after surgery. All patients were evaluated for febrile morbidity and for the development of specific infections. The overall postoperative morbidity was reduced from 51% in the control group to 17% in the mezlocillin group (P less than 0.01). Separate analyses of morbidity in patients undergoing cesarean section after the onset of labor and those having the operation before the onset of labor showed the significant reduction of morbidity by mezlocillin to have occurred only in the former group.

Adult↗