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Biomedical subjects

M Aikawa

Publications and source records attributed to M Aikawa.

At least 361 records · Page 20Linked to original sources
PubMed1972

High-resolution autoradiography of malarial parasites treated with 3 H-chloroquine.

Electron microscope autoradiography was performed on the erythrocytic stages of the rodent malarial parasite, Plasmodium berghei, after exposure to (3)H-Chloroquine. (3)H-Chloroquine becomes selectively localized within the parasite food vacuoles 1 hour after it is administered, and remains in this structure for up to 24 hours. This study indicated that the food vacuoles were the primary site of chloroquine concentration within the parasite.

Animals↗
PubMed1971

Erythrocytes: pits and vacuoles as seen with transmission and scanning electron microscopy.

Vacuoles containing inclusions were observed by transmission electron microscopy in erythrocytes of a splenectomized patient with hemoglobin Ann Arbor. The membranes of these vacuoles became fused with the surface membrane of the red cell, thus opening the vacuoles and exposing their contents to the outside. These vacuoles when they have become thus attached to the cell membrane of the erythrocyte are responsible for the pits observed with scanning electron microscopy.

Cytoplasm↗