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Biomedical subjects

M Aggarwal

Publications and source records attributed to M Aggarwal.

12 recordsLinked to original sources

The effect of Cd2+ on lipid components of sunflower (Helianthus annuus L.) seeds.

The effect of seven levels of Cd2+ viz. 0, 10, 20, 30, 40, 60 and 80 ppm (micrograms/g soil) supplied as cadmium chloride, on lipid components of sunflower seeds was studied in a pot experiment. The total and neutral lipids decreased while polar lipids (phospho and glycolipids) increased with the increasing levels of Cd2+. Oleic acid and linoleic acids were the major fatty acids in the total, polar and neutral lipid fractions. Oleic acid generally increased while linoleic acid decreased in all the lipid fractions with Cd2+ levels. The neutral lipid fraction had higher levels of palmitic, palmitoleic, stearic and oleic acid as compared to the total and polar lipid fractions. The plant dry weight and seed yield decreased whereas cadmium concentration in seeds increased consistently with increasing Cd2+ levels.

Cadmium

Henoch-Schönlein vasculitis as a manifestation of IgA-associated disease in cirrhosis.

Cirrhosis has been associated with a variety of glomerular lesions that generally include deposits of IgA in the mesangium. However, loss of renal function secondary to IgA deposition in cirrhotics is infrequent. An unusual patient who developed rapidly progressive glomerulonephritis followed by leukocytoclastic vasculitis with IgA deposition on skin biopsy is presented. We postulate that this is an example of Henoch-Schönlein purpura occurring secondary to altered IgA processing in cirrhosis.

Female

Phagocyte metabolic functions in iron deficiency anaemia of Indian children.

Nitroblue tetrazolium test (NBT) and bactericidal activity of polymorphonuclear leucocytes was studied in 40 patients with iron deficiency anaemia (aged 0-12 years). NBT test had a significant correlation with serum iron (P less than 0.001) in all cases of iron deficiency anemia. Haemoglobin levels less than 4 g/dl also correlated significantly with NBT score. Bactericidal activity with opsonin-coated Staphylococcus aureus was considerably decreased in severe anaemia, but no significant correlation was found with serum iron concentration (P less than 0.1). The phagocytic and bactericidal activity of polymorphonuclear leucocytes is dependent upon serum iron levels and is considerably reduced in iron deficient state in anaemic children.

Anemia, Hypochromic

Interference from renal dialysis patients' specimens in a direct method for serum iron.

In a direct-measuring, sample-blank procedure for serum iron we obtained spuriously high results for renal hemodialysis patients. These spurious results were found to be the result of protein precipitating out of solution owing to anticoagulation of these patients with heparin during hemodialysis. Two methods are described for circumventing this interference: adjusting the pH of the buffer and adding sodium dodecyl sulfate (lauryl sulfate). We prefer the latter procedure for reasons which are discussed, and optimized conditions are described for it. The effects on results by this latter method of bilirubin, hemolysis, and turbidity are described. The method is also evaluated for precision and accuracy, and it is recommended for routine use. A significant "protein effect" (due to viscosity) is noted, which has implications for calibration of the American Monitor KDA instrument.

Autoanalysis

A new powder-free glove with a textured surface to improve handling of surgical instruments.

A latex surgical glove has been designed to have a textured surface that stimulates the surface of intact skin. This textured surface enhances security of grasp of surgical instruments under wet and dry conditions without altering tactile discrimination. The unique hydrogel polymer of this glove allows the glove to be donned with either wet or dry hands without the use of cornstarch lubricants.

Evaluation Studies as Topic