Search PubMed⌕ Search

Biomedical subjects

M Abel

Publications and source records attributed to M Abel.

At least 91 records · Page 5Linked to original sources
PubMed1984

[Colloid osmotic pressure values of respiratory insufficiency in neonates of various gestational ages. Comparative presentation of measured and calculated values].

Colloid osmotic pressure (COP) is an important physiochemical factor in intercompartmental body fluid movements. In actual medical practise COP is notably measured in adult intensive care patients to control oncotic fluid therapy. Recent advances in oncometry technics led to rapid and accurate COP determinations also on very small sample volumes of neonatal intensive care patients. In 47 preterm and term newborns we determined during the first 9 days of life COP changes of calculated and measured values. The COP of patients with respiratory distress was compared to COP levels of newborns without respiratory problems. Until the sixth day of life preterm and term newborns with respiratory insufficiency showed significantly lower COP than normal newborns. The poorest correlation between measured and calculated COP was found in preterm infants with need of respiratory support therapy. During the whole observation period a rise of COP could be observed in all gestational age groups. This tendency should be considered before and during albumin therapy in newborns to avoid oncotic fluid overload, e.g. in a preterm infant. When volume replacement therapy is required in very young patients we advise measurement of COP as a guide to fluid selection.

Gestational Age↗
PubMed1983

[Axillary plexus anesthesia in noncooperative patients].

In 36 non-cooperative patients we performed block of the axillary brachial plexus by using a well recognized catheter technique. A flexible, disposable intravenous cannula was placed into the axillary neurovascular sheath and used for injection of local anaesthetic solution without adverse sequelae. Analgesia for acute and elective surgical procedures was obtained rapidly and independent of any patient's assistance in all cases. Catheter axillary block seems to be a valuable anaesthetic technique in the difficult and risky management of non-cooperative patients.

Adolescent↗
PubMed1983

[Therapeutic regional anesthesia following an accidental intra-arterial injection. A case report on anesthesiologic care following incorrect injection of Reparil (sodium escinate)].

Symptomatology and therapeutic measures after accidental brachial intra-arterial injection of sodium escinate were explained by means of a case report. We obtained long-acting analgesia and sympathicolysis in the upper extremity by an anaesthesia of the ganglion stellatum followed by repeated interscalene plexus brachialis blockade. Even in very severe cases of accidental intra-arterial drug injection surgical procedures should be accompanied with therapeutic regional anaesthesia technics.

Adult↗
PubMed1983

[Perioperative therapy in juvenile pheochromocytoma].

The article reports on the paediatric-anaesthesiological treatment of 6 phaeochromocytomas in 5 children who were 8 to 16 years of age. Therapeutic recommendations for the perioperative medication of infantile phaeochromocytoma patients are involved. The therapeutic aim of this study was the management of the effects of phaeochromocytoma before and after extirpation of the tumour, the effect of the phaeochromocytoma being of an alpha-adrenergic and beta-adrenergic cardiovascular nature and transmitted by catecholamines. Preoperative stabilization of blood pressure by means of the alpha-blocker phenoxybenzamine and a subsequent intraoperative, controlled reduction of blood pressure by means of sodium nitroprusside were found to be an effective, safe and easily appreciated therapeutic concept for the perioperative care of paediatric phaeochromocytoma patients. Considerable individual differences in dose an duration of the necessary preoperative phenoxybenzamine administration rendered ward control of therapy recommendable. The risk of complete alpha-sympathicolysis by additive drug effects during premedication and induction of anaesthesia, had to be taken into consideration for conducting phenoxybenzamine therapy. Additional administration of the beta-blocker pindolol successfully controlled the intraoperatively manifested tachycardial heart rhythm phases without provoking any complicating arrhythmias. During the entire perioperative treatment of the patients it is mandatory to ensure sufficient substitution of intravascular volume to prevent hypotensive complications. Our patients did not need any cardiac and sympathicomimetic drugs as postoperative administration. None of the patients had any perioperative complications worth mentioning.

Adolescent↗
PubMed1982

[On the use of physostigmine in anesthesia and intensive care].

Physostigmine is an antidote in cases of overdosage with intravenous anaesthetics such as dehydrobenzperidol, benzodiazepines and ketamine. It is also useful in antagonizing drug induced comas of different origin particularly in cases of acute intoxication with tricyclic antidepressants and alcohol. We discuss our therapeutic observations in anaesthesiological and intensive care patients. We have not seen any side effects after physostigmine administration, but the possibility of undesired parasympathomimetic activity demands correct indication, well calculated dosage and continuous surveillance of the patient.

Aged↗
PubMed1982

[Blunt neck trauma--the danger of secondary respiratory insufficiency].

It is very difficult to properly assess a lesion of the kind represented by the contuse trauma of the neck, if such assessment has to be effected at the site of the accident. It is a characteristic feature of such a trauma that even hours or days after the accident, acute respiratory insufficiency may suddenly appear if there is an interruption of continuity of the respiratory tract. X-ray and endoscopic findings are mandatory directly after the accident even if it looks as though there are only few signs or symptoms. In case of indication of surgery, all the necessary measures must be taken before initiating anaesthesia to avoid any complications which may be due to hypoxia and aspiration. A case report is given to illustrate the possible discrepancy between the signs immediately after the accident and the findings made later.

Adult↗
PubMed1982

[Osmolarity parameter and kidney function of polytraumatized intensive care patients].

Improved possibilities in prediction of renal failure after polytrauma would possibly improve the survival rate of this severe posttraumatic complication. Our clinical investigation was carried out in 27 patients suffering from severe trauma. We intended to achieve early recognition of acute renal failure by osmolality measurements after polytrauma. Thus we investigated the daily concentration of blood urea, serum and urine creatinine, daily urine output, creatinine clearance, plasma and urine osmolality and the serum colloid osmotic pressure. Additional to important informations for fluid and electrolyte replacement the follow-up of osmolality changes in plasma and urine proved general and renal prognostic value. Early and clear decreases in urine-plasma ration, osmolar clearance and negative free water clearance were found in case of later reduction of renal function and acute renal failure. Consequently we advise regular osmolality measurements in the postoperative management of the polytraumatic patient.

Acute Kidney Injury↗
PubMed1981

[Perioperative opiate analgesia (author's transl)].

22 patients undergoing gynaecological surgery were given general anaesthesia supplemented by epidural morphine during and after the operation. The fentanyl requirements during the operation were significantly lower than they were in a control group and postoperative administration of analgesics could be dispensed with. The method is particularly suitable for patients at risk because less anaesthetic agents are needed. Postoperative epidural opiate analgesia is also useful after epidural anaesthesia; doses of 3.0 mg of morphine produced no side-effects except pruritus.

Anesthesia, Epidural↗
PubMed1978

[3H] 2-Amino-6,7-dihydroxy 1,2,3,4-tetrahydronapthalene (ADTN): a potential specific dopamine receptor ligand.

The characteristics of [3H] 2-amino-6,7-dihydroxy 1,2,3,4-tetrahydronapthalene (ADTN) binding to calf striatal membranes were investigated. [3H]ADTN was observed to bind with high affinity and stereospecificity to a preparation of crude synaptic membranes. A number of dopamine agonists and antagonists were studied for their ability to displace bound [3H]ADTN. Dopamine agonists were found to be more potent inhibitors of ADTN binding than were dopamine antagonists. Kinetic analysis indicates that [3H]ADTN binds to dopamine recognition sites in a manner comparable to dopamine itself. Overall, the data suggest that ADTN may be a useful ligand for the characterization of agonist requirements for recognition by dopamine binding sites.

Animals↗
PubMed1976

Bacteriology of the socket in patients with prostheses.

Fifty-two unilaterally enucleated patients were studied for symptoms, signs, and actual presence of bacteria in the socket and fellow eye. The majority (85%) of asymptomatic sockets were found to have a mixed culture of pathogenic organisms. Sockets had a significantly (P = .001) greater frequency of pathogenic organisms than the fellow eye. Cross contamination does not appear frequently but is a definite possibility. We recommend culture and treatment of the asymptomatic socket before surgery on the remaining eye.

Adolescent↗